Methylation-mediated transcriptional repression of microRNAs during cervical carcinogenesis

References

• Bosch FX, Lorincz A, Muñoz N, Meijer CJ, Shah KV. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol 2002; 55:244 - 65; http://dx.doi.org/10.1136/jcp.55.4.244; PMID: 11919208
   PubMed Web of Science ®Google Scholar
• Walboomers JM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 1999; 189:12 - 9; http://dx.doi.org/10.1002/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F; PMID: 10451482
   PubMed Web of Science ®Google Scholar
• Steenbergen RD, de Wilde J, Wilting SM, Brink AA, Snijders PJ, Meijer CJ. HPV-mediated transformation of the anogenital tract. J Clin Virol 2005; 32:Suppl 1 S25 - 33; http://dx.doi.org/10.1016/j.jcv.2004.11.019; PMID: 15753009
   PubMed Web of Science ®Google Scholar
• Botezatu A, Goia-Rusanu CD, Iancu IV, Huica I, Plesa A, Socolov D, et al. Quantitative analysis of the relationship between microRNA‑124a, -34b and -203 gene methylation and cervical oncogenesis. Mol Med Report 2011; 4:121 - 8; PMID: 21461574
   PubMed Web of Science ®Google Scholar
• Wilting SM, van Boerdonk RA, Henken FE, Meijer CJ, Diosdado B, Meijer GA, et al. Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer. Mol Cancer 2010; 9:167 - 81; http://dx.doi.org/10.1186/1476-4598-9-167; PMID: 20579385
   PubMed Web of Science ®Google Scholar
• Wilting SM, Snijders PJ, Verlaat W, Jaspers A, van de Wiel MA, van Wieringen WN, et al. Altered microRNA expression associated with chromosomal changes contributes to cervical carcinogenesis. Oncogene 2012; In press http://dx.doi.org/10.1038/onc.2012.20; PMID: 22330141
   PubMed Web of Science ®Google Scholar
• Weber B, Stresemann C, Brueckner B, Lyko F. Methylation of human microRNA genes in normal and neoplastic cells. Cell Cycle 2007; 6:1001 - 5; http://dx.doi.org/10.4161/cc.6.9.4209; PMID: 17457051
   PubMed Web of Science ®Google Scholar
• Lopez-Serra P, Esteller M. DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer. Oncogene 2012; 31:1609 - 22; http://dx.doi.org/10.1038/onc.2011.354; PMID: 21860412
   PubMed Web of Science ®Google Scholar
• Henken FE, Wilting SM, Overmeer RM, van Rietschoten JG, Nygren AO, Errami A, et al. Sequential gene promoter methylation during HPV-induced cervical carcinogenesis. Br J Cancer 2007; 97:1457 - 64; http://dx.doi.org/10.1038/sj.bjc.6604055; PMID: 17971771
   PubMed Web of Science ®Google Scholar
• Steenbergen RD, Parker JN, Isern S, Snijders PJ, Walboomers JM, Meijer CJ, et al. Viral E6-E7 transcription in the basal layer of organotypic cultures without apparent p21cip1 protein precedes immortalization of human papillomavirus type 16- and 18-transfected human keratinocytes. J Virol 1998; 72:749 - 57; PMID: 9420282
   PubMed Web of Science ®Google Scholar
• Wilting SM, Snijders PJ, Meijer GA, Ylstra B, van den Ijssel PR, Snijders AM, et al. Increased gene copy numbers at chromosome 20q are frequent in both squamous cell carcinomas and adenocarcinomas of the cervix. J Pathol 2006; 209:220 - 30; http://dx.doi.org/10.1002/path.1966; PMID: 16538612
   PubMed Web of Science ®Google Scholar
• Overmeer RM, Henken FE, Bierkens M, Wilting SM, Timmerman I, Meijer CJ, et al. Repression of MAL tumor suppressor activity by promoter methylation during cervical carcinogenesis. J Pathol 2009; 9:327 - 36; http://dx.doi.org/10.1002/path.2598
   Web of Science ®Google Scholar
• Steenbergen RD, Kramer D, Braakhuis BJ, Stern PL, Verheijen RH, Meijer CJ, et al. TSLC1 gene silencing in cervical cancer cell lines and cervical neoplasia. J Natl Cancer Inst 2004; 96:294 - 305; http://dx.doi.org/10.1093/jnci/djh031; PMID: 14970278
   PubMed Web of Science ®Google Scholar
• Bierkens M, Krijgsman O, Wilting SM, Bosch L, Jaspers A, Meijer GA, et al. Focal aberrations indicate EYA2 and hsa-miR-375 as oncogene and tumor suppressor in cervical carcinogenesis. Genes Chromosomes Cancer 2012; In press http://dx.doi.org/10.1002/gcc.22006; PMID: 22987659
   PubMed Web of Science ®Google Scholar
• Wang F, Li Y, Zhou J, Xu J, Peng C, Ye F, et al. miR-375 is down-regulated in squamous cervical cancer and inhibits cell migration and invasion via targeting transcription factor SP1. Am J Pathol 2011; 179:2580 - 8; http://dx.doi.org/10.1016/j.ajpath.2011.07.037; PMID: 21945323
   PubMed Web of Science ®Google Scholar
• Brenet F, Moh M, Funk P, Feierstein E, Viale AJ, Socci ND, et al. DNA methylation of the first exon is tightly linked to transcriptional silencing. PLoS One 2011; 6:e14524; http://dx.doi.org/10.1371/journal.pone.0014524; PMID: 21267076
   PubMed Web of Science ®Google Scholar
• Wang F, Ma YL, Zhang P, Shen TY, Shi CZ, Yang YZ, et al. SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer. J Pathol 2012; In press http://dx.doi.org/10.1002/path.4078; PMID: 22821729
   PubMed Web of Science ®Google Scholar
• Zhang Z, Zhang B, Li W, Fu L, Fu L, Zhu Z, et al. Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer Cells. Genes Cancer 2011; 2:782 - 91; http://dx.doi.org/10.1177/1947601911429743; PMID: 22393463
   PubMedGoogle Scholar
• Melar-New M, Laimins LA. Human papillomaviruses modulate expression of microRNA 203 upon epithelial differentiation to control levels of p63 proteins. J Virol 2010; 84:5212 - 21; http://dx.doi.org/10.1128/JVI.00078-10; PMID: 20219920
   PubMed Web of Science ®Google Scholar
• McKenna DJ, McDade SS, Patel D, McCance DJ. MicroRNA 203 expression in keratinocytes is dependent on regulation of p53 levels by E6. J Virol 2010; 84:10644 - 52; http://dx.doi.org/10.1128/JVI.00703-10; PMID: 20702634
   PubMed Web of Science ®Google Scholar
• Furuta M, Kozaki KI, Tanaka S, Arii S, Imoto I, Inazawa J. miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis 2010; 31:766 - 76; http://dx.doi.org/10.1093/carcin/bgp250; PMID: 19843643
   PubMed Web of Science ®Google Scholar
• Kozaki K, Imoto I, Mogi S, Omura K, Inazawa J. Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res 2008; 68:2094 - 105; http://dx.doi.org/10.1158/0008-5472.CAN-07-5194; PMID: 18381414
   PubMed Web of Science ®Google Scholar
• Li X, Lin R, Li J. Epigenetic silencing of microRNA-375 regulates PDK1 expression in esophageal cancer. Dig Dis Sci 2011; 56:2849 - 56; http://dx.doi.org/10.1007/s10620-011-1711-1; PMID: 21533613
   PubMed Web of Science ®Google Scholar
• Wiklund ED, Gao S, Hulf T, Sibbritt T, Nair S, Costea DE, et al. MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma. PLoS One 2011; 6:e27840; http://dx.doi.org/10.1371/journal.pone.0027840; PMID: 22132151
   PubMed Web of Science ®Google Scholar
• de Souza Rocha Simonini P, Breiling A, Gupta N, Malekpour M, Youns M, Omranipour R, et al. Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells. Cancer Res 2010; 70:9175 - 84; http://dx.doi.org/10.1158/0008-5472.CAN-10-1318; PMID: 20978187
   PubMed Web of Science ®Google Scholar
• Eijsink JJ, Lendvai A, Deregowski V, Klip HG, Verpooten G, Dehaspe L, et al. A four-gene methylation marker panel as triage test in high-risk human papillomavirus positive patients. Int J Cancer 2012; 130:1861 - 9; http://dx.doi.org/10.1002/ijc.26326; PMID: 21796628
   PubMed Web of Science ®Google Scholar
• Hesselink AT, Heideman DA, Steenbergen RD, Coupé VM, Overmeer RM, Rijkaart D, et al. Combined promoter methylation analysis of CADM1 and MAL: an objective triage tool for high-risk human papillomavirus DNA-positive women. Clin Cancer Res 2011; 17:2459 - 65; http://dx.doi.org/10.1158/1078-0432.CCR-10-2548; PMID: 21389098
   PubMed Web of Science ®Google Scholar
• Steenbergen RD, Walboomers JM, Meijer CJ, van der Raaij-Helmer EM, Parker JN, Chow LT, et al. Transition of human papillomavirus type 16 and 18 transfected human foreskin keratinocytes towards immortality: activation of telomerase and allele losses at 3p, 10p, 11q and/or 18q. Oncogene 1996; 13:1249 - 57; PMID: 8808699
   PubMed Web of Science ®Google Scholar
• Steenbergen RD, Kramer D, Meijer CJ, Walboomers JM, Trott DA, Cuthbert AP, et al. Telomerase suppression by chromosome 6 in a human papillomavirus type 16-immortalized keratinocyte cell line and in a cervical cancer cell line. J Natl Cancer Inst 2001; 93:865 - 72; http://dx.doi.org/10.1093/jnci/93.11.865; PMID: 11390536
   PubMed Web of Science ®Google Scholar
• Jacobs MV, Snijders PJ, van den Brule AJ, Helmerhorst TJ, Meijer CJ, Walboomers JM. A general primer GP5+/GP6(+)-mediated PCR-enzyme immunoassay method for rapid detection of 14 high-risk and 6 low-risk human papillomavirus genotypes in cervical scrapings. J Clin Microbiol 1997; 35:791 - 5; PMID: 9041439
   PubMed Web of Science ®Google Scholar
• Bulkmans NW, Berkhof J, Rozendaal L, van Kemenade FJ, Boeke AJ, Bulk S, et al. Human papillomavirus DNA testing for the detection of cervical intraepithelial neoplasia grade 3 and cancer: 5-year follow-up of a randomised controlled implementation trial. Lancet 2007; 370:1764 - 72; http://dx.doi.org/10.1016/S0140-6736(07)61450-0; PMID: 17919718
   PubMed Web of Science ®Google Scholar
• Rijkaart DC, Berkhof J, Rozendaal L, van Kemenade FJ, Bulkmans NW, Heideman DA, et al. Human papillomavirus testing for the detection of high-grade cervical intraepithelial neoplasia and cancer: final results of the POBASCAM randomised controlled trial. Lancet Oncol 2012; 13:78 - 88; http://dx.doi.org/10.1016/S1470-2045(11)70296-0; PMID: 22177579
   PubMed Web of Science ®Google Scholar
• Gardiner-Garden M, Frommer M. CpG islands in vertebrate genomes. J Mol Biol 1987; 196:261 - 82; http://dx.doi.org/10.1016/0022-2836(87)90689-9; PMID: 3656447
   PubMed Web of Science ®Google Scholar
• van Zeeburg HJ, Snijders PJ, Pals G, Hermsen MA, Rooimans MA, Bagby G, et al. Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients. Cancer Res 2005; 65:1271 - 6; http://dx.doi.org/10.1158/0008-5472.CAN-04-3665; PMID: 15735012
   PubMed Web of Science ®Google Scholar
• Overmeer RM, Henken FE, Snijders PJ, Claassen-Kramer D, Berkhof J, Helmerhorst TJ, et al. Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC. J Pathol 2008; 215:388 - 97; http://dx.doi.org/10.1002/path.2367; PMID: 18498117
   PubMed Web of Science ®Google Scholar
• Harden SV, Guo Z, Epstein JI, Sidransky D. Quantitative GSTP1 methylation clearly distinguishes benign prostatic tissue and limited prostate adenocarcinoma. J Urol 2003; 169:1138 - 42; http://dx.doi.org/10.1097/01.ju.0000049627.90307.4d; PMID: 12576869
   PubMed Web of Science ®Google Scholar
• Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 2008; 3:1101 - 8; http://dx.doi.org/10.1038/nprot.2008.73; PMID: 18546601
   PubMed Web of Science ®Google Scholar
• Voorhoeve PM, le Sage C, Schrier M, Gillis AJ, Stoop H, Nagel R, et al. A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 2006; 124:1169 - 81; http://dx.doi.org/10.1016/j.cell.2006.02.037; PMID: 16564011
   PubMed Web of Science ®Google Scholar