A genome-wide methylation study on obesity

References

• Feinberg AP, Irizarry RA. Evolution in health and medicine Sackler colloquium: Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease. Proc Natl Acad Sci U S A 2010; 107:Suppl 1 1757 - 64; http://dx.doi.org/10.1073/pnas.0906183107; PMID: 20080672
   PubMed Web of Science ®Google Scholar
• Hansen KD, Timp W, Bravo HC, Sabunciyan S, Langmead B, McDonald OG, et al. Increased methylation variation in epigenetic domains across cancer types. Nat Genet 2011; 43:768 - 75; http://dx.doi.org/10.1038/ng.865; PMID: 21706001
   PubMed Web of Science ®Google Scholar
• Teschendorff AE, Jones A, Fiegl H, Sargent A, Zhuang JJ, Kitchener HC, et al. Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation. Genome Med 2012; 4:24; http://dx.doi.org/10.1186/gm323; PMID: 22453031
   PubMed Web of Science ®Google Scholar
• Teschendorff AE, Widschwendter M. Differential variability improves the identification of cancer risk markers in DNA methylation studies profiling precursor cancer lesions. Bioinformatics 2012; 28:1487 - 94; http://dx.doi.org/10.1093/bioinformatics/bts170; PMID: 22492641
   PubMed Web of Science ®Google Scholar
• Danaei G, Ding EL, Mozaffarian D, Taylor B, Rehm J, Murray CJ, et al. The preventable causes of death in the United States: comparative risk assessment of dietary, lifestyle, and metabolic risk factors. PLoS Med 2009; 6:e1000058; http://dx.doi.org/10.1371/journal.pmed.1000058; PMID: 19399161
   PubMed Web of Science ®Google Scholar
• Misra A, Khurana L. Obesity and the metabolic syndrome in developing countries. J Clin Endocrinol Metab 2008; 93:Suppl 1 S9 - 30; http://dx.doi.org/10.1210/jc.2008-1595; PMID: 18987276
   PubMed Web of Science ®Google Scholar
• Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, et al, American Heart Association, Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 2006; 113:898 - 918; http://dx.doi.org/10.1161/CIRCULATIONAHA.106.171016; PMID: 16380542
   PubMed Web of Science ®Google Scholar
• El-Atat F, Aneja A, Mcfarlane S, Sowers J. Obesity and hypertension. Endocrinol Metab Clin North Am 2003; 32:823 - 54; http://dx.doi.org/10.1016/S0889-8529(03)00070-7; PMID: 14711064
   PubMed Web of Science ®Google Scholar
• Rathmann W, Giani G. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004; 27:2568 - 9, author reply 2569; http://dx.doi.org/10.2337/diacare.27.10.2568; PMID: 15451946
   PubMed Web of Science ®Google Scholar
• Anderson AS, Caswell S. Obesity management--an opportunity for cancer prevention. Surgeon 2009; 7:282 - 5; http://dx.doi.org/10.1016/S1479-666X(09)80005-X; PMID: 19848061
   PubMed Web of Science ®Google Scholar
• Morimoto LM, White E, Chen Z, Chlebowski RT, Hays J, Kuller L, et al. Obesity, body size, and risk of postmenopausal breast cancer: the Women’s Health Initiative (United States). Cancer Causes Control 2002; 13:741 - 51; http://dx.doi.org/10.1023/A:1020239211145; PMID: 12420953
   PubMed Web of Science ®Google Scholar
• Larsson SC, Wolk A. Obesity and colon and rectal cancer risk: a meta-analysis of prospective studies. Am J Clin Nutr 2007; 86:556 - 65; PMID: 17823417
   PubMed Web of Science ®Google Scholar
• Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser 2000; 894:i - xii, 1-253; PMID: 11234459
   PubMed Web of Science ®Google Scholar
• Wang X, Zhu H, Snieder H, Su S, Munn D, Harshfield G, et al. Obesity related methylation changes in DNA of peripheral blood leukocytes. BMC Med 2010; 8:87; http://dx.doi.org/10.1186/1741-7015-8-87; PMID: 21176133
   PubMed Web of Science ®Google Scholar
• Feinberg AP, Irizarry RA, Fradin D, Aryee MJ, Murakami P, Aspelund T, et al. Personalized epigenomic signatures that are stable over time and covary with body mass index. Sci Transl Med 2010; 2:49ra67; http://dx.doi.org/10.1126/scitranslmed.3001262; PMID: 20844285
   PubMed Web of Science ®Google Scholar
• Toperoff G, Aran D, Kark JD, Rosenberg M, Dubnikov T, Nissan B, et al. Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood. Hum Mol Genet 2012; 21:371 - 83; http://dx.doi.org/10.1093/hmg/ddr472; PMID: 21994764
   PubMed Web of Science ®Google Scholar
• Liu Y, Aryee MJ, Padyukov L, Fallin MD, Hesselberg E, Runarsson A, et al. Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol 2013; 31:142 - 7; http://dx.doi.org/10.1038/nbt.2487; PMID: 23334450
   PubMed Web of Science ®Google Scholar
• Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, et al. FTO genotype is associated with phenotypic variability of body mass index. Nature 2012; 490:267 - 72; http://dx.doi.org/10.1038/nature11401; PMID: 22982992
   PubMed Web of Science ®Google Scholar
• Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004; 3:e3; http://dx.doi.org/10.2202/1544-6115.1027; PMID: 16646809
   PubMedGoogle Scholar
• Tibshirani R, Hastie T, Narasimhan B, Chu G. Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc Natl Acad Sci U S A 2002; 99:6567 - 72; http://dx.doi.org/10.1073/pnas.082099299; PMID: 12011421
   PubMed Web of Science ®Google Scholar
• Hochberg Y, Benjamini Y. More powerful procedures for multiple significance testing. Stat Med 1990; 9:811 - 8; http://dx.doi.org/10.1002/sim.4780090710; PMID: 2218183
   PubMed Web of Science ®Google Scholar