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Research Paper

Association between hypermethylation of DNA repetitive elements in white blood cell DNA and early-onset colorectal cancer

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Pages 748-755 | Received 29 Apr 2013, Accepted 24 May 2013, Published online: 17 Jun 2013

References

  • Zauber AG, Winawer SJ, O’Brien MJ, Lansdorp-Vogelaar I, van Ballegooijen M, Hankey BF, et al. Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med 2012; 366:687 - 96; http://dx.doi.org/10.1056/NEJMoa1100370; PMID: 22356322
  • Smith RA, Cokkinides V, Brawley OW. Cancer screening in the United States, 2009: a review of current American Cancer Society guidelines and issues in cancer screening. CA Cancer J Clin 2009; 59:27 - 41; http://dx.doi.org/10.3322/caac.20008; PMID: 19147867
  • Levin B, Lieberman DA, McFarland B, Smith RA, Brooks D, Andrews KS, et al, American Cancer Society Colorectal Cancer Advisory Group, US Multi-Society Task Force, American College of Radiology Colon Cancer Committee. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. CA Cancer J Clin 2008; 58:130 - 60; http://dx.doi.org/10.3322/CA.2007.0018; PMID: 18322143
  • Siegel RL, Jemal A, Ward EM. Increase in incidence of colorectal cancer among young men and women in the United States. Cancer Epidemiol Biomarkers Prev 2009; 18:1695 - 8; http://dx.doi.org/10.1158/1055-9965.EPI-09-0186; PMID: 19505901
  • Terry MB, Delgado-Cruzata L, Vin-Raviv N, Wu HC, Santella RM. DNA methylation in white blood cells: association with risk factors in epidemiologic studies. Epigenetics 2011; 6:828 - 37; http://dx.doi.org/10.4161/epi.6.7.16500; PMID: 21636973
  • Moore LE, Pfeiffer RM, Poscablo C, Real FX, Kogevinas M, Silverman D, et al. Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study. Lancet Oncol 2008; 9:359 - 66; http://dx.doi.org/10.1016/S1470-2045(08)70038-X; PMID: 18339581
  • Liao LM, Brennan P, van Bemmel DM, Zaridze D, Matveev V, Janout V, et al. LINE-1 methylation levels in leukocyte DNA and risk of renal cell cancer. PLoS One 2011; 6:e27361; http://dx.doi.org/10.1371/journal.pone.0027361; PMID: 22076155
  • Hsiung DT, Marsit CJ, Houseman EA, Eddy K, Furniss CS, McClean MD, et al. Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 2007; 16:108 - 14; http://dx.doi.org/10.1158/1055-9965.EPI-06-0636; PMID: 17220338
  • Choi JY, James SR, Link PA, McCann SE, Hong CC, Davis W, et al. Association between global DNA hypomethylation in leukocytes and risk of breast cancer. Carcinogenesis 2009; 30:1889 - 97; http://dx.doi.org/10.1093/carcin/bgp143; PMID: 19584139
  • Weisenberger DJ, Campan M, Long TI, Kim M, Woods C, Fiala E, et al. Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res 2005; 33:6823 - 36; http://dx.doi.org/10.1093/nar/gki987; PMID: 16326863
  • Jordan IK, Rogozin IB, Glazko GV, Koonin EV. Origin of a substantial fraction of human regulatory sequences from transposable elements. Trends Genet 2003; 19:68 - 72; http://dx.doi.org/10.1016/S0168-9525(02)00006-9; PMID: 12547512
  • Weiner AM. SINEs and LINEs: the art of biting the hand that feeds you. Curr Opin Cell Biol 2002; 14:343 - 50; http://dx.doi.org/10.1016/S0955-0674(02)00338-1; PMID: 12067657
  • Cordaux R, Batzer MA. The impact of retrotransposons on human genome evolution. Nat Rev Genet 2009; 10:691 - 703; http://dx.doi.org/10.1038/nrg2640; PMID: 19763152
  • Zhu ZZ, Sparrow D, Hou L, Tarantini L, Bollati V, Litonjua AA, et al. Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study. Cancer Causes Control 2011; 22:437 - 47; http://dx.doi.org/10.1007/s10552-010-9715-2; PMID: 21188491
  • Wu HC, Delgado-Cruzata L, Flom JD, Perrin M, Liao Y, Ferris JS, et al. Repetitive element DNA methylation levels in white blood cell DNA from sisters discordant for breast cancer from the New York site of the Breast Cancer Family Registry. Carcinogenesis 2012; 33:1946 - 52; http://dx.doi.org/10.1093/carcin/bgs201; PMID: 22678115
  • Gao Y, Baccarelli A, Shu XO, Ji BT, Yu K, Tarantini L, et al. Blood leukocyte Alu and LINE-1 methylation and gastric cancer risk in the Shanghai Women’s Health Study. Br J Cancer 2012; 106:585 - 91; http://dx.doi.org/10.1038/bjc.2011.562; PMID: 22173668
  • Pufulete M, Al-Ghnaniem R, Leather AJ, Appleby P, Gout S, Terry C, et al. Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study. Gastroenterology 2003; 124:1240 - 8; http://dx.doi.org/10.1016/S0016-5085(03)00279-8; PMID: 12730865
  • Lim U, Flood A, Choi SW, Albanes D, Cross AJ, Schatzkin A, et al. Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women. Gastroenterology 2008; 134:47 - 55; http://dx.doi.org/10.1053/j.gastro.2007.10.013; PMID: 18166347
  • Nan H, Giovannucci EL, Wu K, Selhub J, Paul L, Rosner B, et al. Pre-diagnostic leukocyte genomic DNA methylation and the risk of colorectal cancer in women. PLoS One 2013; 8:e59455; http://dx.doi.org/10.1371/journal.pone.0059455; PMID: 23560049
  • Kitkumthorn N, Tuangsintanakul T, Rattanatanyong P, Tiwawech D, Mutirangura A. LINE-1 methylation in the peripheral blood mononuclear cells of cancer patients. Clin Chim Acta 2012; 413:869 - 74; http://dx.doi.org/10.1016/j.cca.2012.01.024; PMID: 22326975
  • Brennan K, Flanagan JM. Is there a link between genome-wide hypomethylation in blood and cancer risk?. Cancer Prev Res (Phila) 2012; 5:1345 - 57; http://dx.doi.org/10.1158/1940-6207.CAPR-12-0316; PMID: 23135621
  • Suzuki K, Suzuki I, Leodolter A, Alonso S, Horiuchi S, Yamashita K, et al. Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage. Cancer Cell 2006; 9:199 - 207; http://dx.doi.org/10.1016/j.ccr.2006.02.016; PMID: 16530704
  • Fuke C, Shimabukuro M, Petronis A, Sugimoto J, Oda T, Miura K, et al. Age related changes in 5-methylcytosine content in human peripheral leukocytes and placentas: an HPLC-based study. Ann Hum Genet 2004; 68:196 - 204; http://dx.doi.org/10.1046/j.1529-8817.2004.00081.x; PMID: 15180700
  • Yang AS, Estécio MR, Doshi K, Kondo Y, Tajara EH, Issa JP. A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res 2004; 32:e38; http://dx.doi.org/10.1093/nar/gnh032; PMID: 14973332
  • Xu X, Gammon MD, Hernandez-Vargas H, Herceg Z, Wetmur JG, Teitelbaum SL, et al. DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study. FASEB J 2012; 26:2657 - 66; http://dx.doi.org/10.1096/fj.11-197251; PMID: 22371529
  • Woo HD, Kim J. Global DNA hypomethylation in peripheral blood leukocytes as a biomarker for cancer risk: a meta-analysis. PLoS One 2012; 7:e34615; http://dx.doi.org/10.1371/journal.pone.0034615; PMID: 22509334
  • Langevin SM, Koestler DC, Christensen BC, Butler RA, Wiencke JK, Nelson HH, et al. Peripheral blood DNA methylation profiles are indicative of head and neck squamous cell carcinoma: an epigenome-wide association study. Epigenetics 2012; 7:291 - 9; http://dx.doi.org/10.4161/epi.7.3.19134; PMID: 22430805
  • Chen RZ, Pettersson U, Beard C, Jackson-Grusby L, Jaenisch R. DNA hypomethylation leads to elevated mutation rates. Nature 1998; 395:89 - 93; http://dx.doi.org/10.1038/25779; PMID: 9738504
  • Pornthanakasem W, Kongruttanachok N, Phuangphairoj C, Suyarnsestakorn C, Sanghangthum T, Oonsiri S, et al. LINE-1 methylation status of endogenous DNA double-strand breaks. Nucleic Acids Res 2008; 36:3667 - 75; http://dx.doi.org/10.1093/nar/gkn261; PMID: 18474527
  • Segura-Pacheco B, Perez-Cardenas E, Taja-Chayeb L, Chavez-Blanco A, Revilla-Vazquez A, Benitez-Bribiesca L, et al. Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine. J Transl Med 2006; 4:32; http://dx.doi.org/10.1186/1479-5876-4-32; PMID: 16893460
  • Ren J, Singh BN, Huang Q, Li Z, Gao Y, Mishra P, et al. DNA hypermethylation as a chemotherapy target. Cell Signal 2011; 23:1082 - 93; http://dx.doi.org/10.1016/j.cellsig.2011.02.003; PMID: 21345368
  • Candelaria M, de la Cruz-Hernandez E, Taja-Chayeb L, Perez-Cardenas E, Trejo-Becerril C, Gonzalez-Fierro A, et al. DNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cells. PLoS One 2012; 7:e29181; http://dx.doi.org/10.1371/journal.pone.0029181; PMID: 22427797
  • Stern LL, Mason JB, Selhub J, Choi SW. Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene. Cancer Epidemiol Biomarkers Prev 2000; 9:849 - 53; PMID: 10952104
  • Zhang Y, Chen H. Genistein, an epigenome modifier during cancer prevention. Epigenetics 2011; 6:888 - 91; http://dx.doi.org/10.4161/epi.6.7.16315; PMID: 21610327
  • Chanda S, Dasgupta UB, Guhamazumder D, Gupta M, Chaudhuri U, Lahiri S, et al. DNA hypermethylation of promoter of gene p53 and p16 in arsenic-exposed people with and without malignancy. Toxicol Sci 2006; 89:431 - 7; http://dx.doi.org/10.1093/toxsci/kfj030; PMID: 16251483
  • Zhang FF, Cardarelli R, Carroll J, Zhang S, Fulda KG, Gonzalez K, et al. Physical activity and global genomic DNA methylation in a cancer-free population. Epigenetics 2011; 6:293 - 9; http://dx.doi.org/10.4161/epi.6.3.14378; PMID: 21178401
  • Reinius LE, Acevedo N, Joerink M, Pershagen G, Dahlén SE, Greco D, et al. Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility. PLoS One 2012; 7:e41361; http://dx.doi.org/10.1371/journal.pone.0041361; PMID: 22848472
  • Toft P, Svendsen P, Tønnesen E, Rasmussen JW, Christensen NJ. Redistribution of lymphocytes after major surgical stress. Acta Anaesthesiol Scand 1993; 37:245 - 9; http://dx.doi.org/10.1111/j.1399-6576.1993.tb03708.x; PMID: 8517098
  • Newcomb PA, Baron J, Cotterchio M, Gallinger S, Grove J, Haile R, et al, Colon Cancer Family Registry. Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer. Cancer Epidemiol Biomarkers Prev 2007; 16:2331 - 43; http://dx.doi.org/10.1158/1055-9965.EPI-07-0648; PMID: 17982118
  • Lindor NM, Burgart LJ, Leontovich O, Goldberg RM, Cunningham JM, Sargent DJ, et al. Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. J Clin Oncol 2002; 20:1043 - 8; http://dx.doi.org/10.1200/JCO.20.4.1043; PMID: 11844828
  • Cicek MS, Lindor NM, Gallinger S, Bapat B, Hopper JL, Jenkins MA, et al. Quality assessment and correlation of microsatellite instability and immunohistochemical markers among population- and clinic-based colorectal tumors results from the Colon Cancer Family Registry. J Mol Diagn 2011; 13:271 - 81; http://dx.doi.org/10.1016/j.jmoldx.2010.12.004; PMID: 21497289
  • Walsh MD, Cummings MC, Buchanan DD, Dambacher WM, Arnold S, McKeone D, et al. Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patients. Clin Cancer Res 2008; 14:1692 - 700; http://dx.doi.org/10.1158/1078-0432.CCR-07-1849; PMID: 18310315
  • Eads CA, Danenberg KD, Kawakami K, Saltz LB, Blake C, Shibata D, et al. MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res 2000; 28:E32; http://dx.doi.org/10.1093/nar/28.8.e32; PMID: 10734209
  • Poynter JN, Siegmund KD, Weisenberger DJ, Long TI, Thibodeau SN, Lindor N, et al, Colon Cancer Family Registry Investigators. Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening. Cancer Epidemiol Biomarkers Prev 2008; 17:3208 - 15; http://dx.doi.org/10.1158/1055-9965.EPI-08-0512; PMID: 18990764
  • Buchanan DD, Sweet K, Drini M, Jenkins MA, Win AK, English DR, et al. Risk factors for colorectal cancer in patients with multiple serrated polyps: a cross-sectional case series from genetics clinics. PLoS One 2010; 5:e11636; http://dx.doi.org/10.1371/journal.pone.0011636; PMID: 20661287
  • Clendenning M, Hampel H, LaJeunesse J, Lindblom A, Lockman J, Nilbert M, et al. Long-range PCR facilitates the identification of PMS2-specific mutations. Hum Mutat 2006; 27:490 - 5; http://dx.doi.org/10.1002/humu.20318; PMID: 16619239
  • Walsh MD, Buchanan DD, Cummings MC, Pearson SA, Arnold ST, Clendenning M, et al. Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry. Clin Cancer Res 2010; 16:2214 - 24; http://dx.doi.org/10.1158/1078-0432.CCR-09-3058; PMID: 20215533
  • Senter L, Clendenning M, Sotamaa K, Hampel H, Green J, Potter JD, et al. The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations. Gastroenterology 2008; 135:419 - 28; http://dx.doi.org/10.1053/j.gastro.2008.04.026; PMID: 18602922
  • Cleary SP, Cotterchio M, Jenkins MA, Kim H, Bristow R, Green R, et al. Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study. Gastroenterology 2009; 136:1251 - 60; http://dx.doi.org/10.1053/j.gastro.2008.12.050; PMID: 19245865
  • Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16:1215; http://dx.doi.org/10.1093/nar/16.3.1215; PMID: 3344216

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