Global DNA methylation in a population with aflatoxin B₁ exposure

References

• Bressac B, Kew M, Wands J, Ozturk M. Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa. Nature 1991; 350:429 - 31; http://dx.doi.org/10.1038/350429a0; PMID: 1672732
   PubMed Web of Science ®Google Scholar
• Hsu IC, Metcalf RA, Sun T, Welsh JA, Wang NJ, Harris CC. Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature 1991; 350:427 - 8; http://dx.doi.org/10.1038/350427a0; PMID: 1849234
   PubMed Web of Science ®Google Scholar
• Lunn RM, Zhang Y-J, Wang L-Y, Chen CJ, Lee PH, Lee CS, et al. p53 mutations, chronic hepatitis B virus infection, and aflatoxin exposure in hepatocellular carcinoma in Taiwan. Cancer Res 1997; 57:3471 - 7; PMID: 9270015
   PubMed Web of Science ®Google Scholar
• Forrester LM, Neal GE, Judah DJ, Glancey MJ, Wolf CR. Evidence for involvement of multiple forms of cytochrome P-450 in aflatoxin B1 metabolism in human liver. Proc Natl Acad Sci U S A 1990; 87:8306 - 10; http://dx.doi.org/10.1073/pnas.87.21.8306; PMID: 2122459
   PubMed Web of Science ®Google Scholar
• Essigmann JM, Croy RG, Nadzan AM, Busby WF Jr., Reinhold VN, Büchi G, et al. Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro. Proc Natl Acad Sci U S A 1977; 74:1870 - 4; http://dx.doi.org/10.1073/pnas.74.5.1870; PMID: 266709
   PubMed Web of Science ®Google Scholar
• Gallagher EP, Wienkers LC, Stapleton PL, Kunze KL, Eaton DL. Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1. Cancer Res 1994; 54:101 - 8; PMID: 8261428
   PubMed Web of Science ®Google Scholar
• Sabbioni G, Skipper PL, Büchi G, Tannenbaum SR. Isolation and characterization of the major serum albumin adduct formed by aflatoxin B1 in vivo in rats. Carcinogenesis 1987; 8:819 - 24; http://dx.doi.org/10.1093/carcin/8.6.819; PMID: 3111739
   PubMed Web of Science ®Google Scholar
• Wu HC, Santella R. The role of aflatoxins in hepatocellular carcinoma. Hepat Mon 2012; 12:10 HCC e7238; http://dx.doi.org/10.5812/hepatmon.7238; PMID: 23162603
   PubMed Web of Science ®Google Scholar
• Wang LY, Hatch MC, Chen CJ, Levin B, You SL, Lu SN, et al. Aflatoxin exposure and risk of hepatocellular carcinoma in Taiwan. Int J Cancer 1996; 67:620 - 5; http://dx.doi.org/10.1002/(SICI)1097-0215(19960904)67:5<620::AID-IJC5>3.0.CO;2-W; PMID: 8782648
   PubMed Web of Science ®Google Scholar
• Chen CJ, Wang LY, Lu SN, Wu MH, You SL, Zhang YJ, et al. Elevated aflatoxin exposure and increased risk of hepatocellular carcinoma. Hepatology 1996; 24:38 - 42; http://dx.doi.org/10.1002/hep.510240108; PMID: 8707279
   PubMed Web of Science ®Google Scholar
• Sun Z, Lu P, Gail MH, Pee D, Zhang Q, Ming L, et al. Increased risk of hepatocellular carcinoma in male hepatitis B surface antigen carriers with chronic hepatitis who have detectable urinary aflatoxin metabolite M1. Hepatology 1999; 30:379 - 83; http://dx.doi.org/10.1002/hep.510300204; PMID: 10421643
   PubMed Web of Science ®Google Scholar
• Wu H-C, Wang Q, Yang H-I, Ahsan H, Tsai WY, Wang LY, et al. Aflatoxin B1 exposure, hepatitis B virus infection, and hepatocellular carcinoma in Taiwan. Cancer Epidemiol Biomarkers Prev 2009; 18:846 - 53; http://dx.doi.org/10.1158/1055-9965.EPI-08-0697; PMID: 19273485
   PubMed Web of Science ®Google Scholar
• Ross RK, Yuan JM, Yu MC, Wogan GN, Qian GS, Tu JT, et al. Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma. Lancet 1992; 339:943 - 6; http://dx.doi.org/10.1016/0140-6736(92)91528-G; PMID: 1348796
   PubMed Web of Science ®Google Scholar
• Qian GS, Ross RK, Yu MC, Yuan JM, Gao YT, Henderson BE, et al. A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People’s Republic of China. Cancer Epidemiol Biomarkers Prev 1994; 3:3 - 10; PMID: 8118382
   PubMed Web of Science ®Google Scholar
• Chen CJ, Yu MW, Liaw YF, Wang LW, Chiamprasert S, Matin F, et al. Chronic hepatitis B carriers with null genotypes of glutathione S-transferase M1 and T1 polymorphisms who are exposed to aflatoxin are at increased risk of hepatocellular carcinoma. Am J Hum Genet 1996; 59:128 - 34; PMID: 8659516
   PubMed Web of Science ®Google Scholar
• Yu M-W, Lien J-P, Chiu Y-H, Santella RM, Liaw Y-F, Chen C-J. Effect of aflatoxin metabolism and DNA adduct formation on hepatocellular carcinoma among chronic hepatitis B carriers in Taiwan. J Hepatol 1997; 27:320 - 30; http://dx.doi.org/10.1016/S0168-8278(97)80178-X; PMID: 9288607
   PubMed Web of Science ®Google Scholar
• Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002; 3:415 - 28; PMID: 12042769
   PubMed Web of Science ®Google Scholar
• Ehrlich M. DNA methylation in cancer: too much, but also too little. Oncogene 2002; 21:5400 - 13; http://dx.doi.org/10.1038/sj.onc.1205651; PMID: 12154403
   PubMed Web of Science ®Google Scholar
• Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, et al, International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 2001; 409:860 - 921; http://dx.doi.org/10.1038/35057062; PMID: 11237011
   PubMed Web of Science ®Google Scholar
• Shen J, Wang S, Zhang Y-J, Kappil M, Wu HC, Kibriya MG, et al. Genome-wide DNA methylation profiles in hepatocellular carcinoma. Hepatology 2012; 55:1799 - 808; http://dx.doi.org/10.1002/hep.25569; PMID: 22234943
   PubMed Web of Science ®Google Scholar
• Zhang Y-J, Ahsan H, Chen Y, Lunn RM, Wang LY, Chen SY, et al. High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma. Mol Carcinog 2002; 35:85 - 92; http://dx.doi.org/10.1002/mc.10076; PMID: 12325038
   PubMed Web of Science ®Google Scholar
• Zhang Y-J, Rossner P Jr., Chen Y, Agrawal M, Wang Q, Wang L, et al. Aflatoxin B1 and polycyclic aromatic hydrocarbon adducts, p53 mutations and p16 methylation in liver tissue and plasma of hepatocellular carcinoma patients. Int J Cancer 2006; 119:985 - 91; http://dx.doi.org/10.1002/ijc.21699; PMID: 16570275
   PubMed Web of Science ®Google Scholar
• Zhang YJ, Chen Y, Ahsan H, Lunn RM, Chen SY, Lee PH, et al. Silencing of glutathione S-transferase P1 by promoter hypermethylation and its relationship to environmental chemical carcinogens in hepatocellular carcinoma. Cancer Lett 2005; 221:135 - 43; http://dx.doi.org/10.1016/j.canlet.2004.08.028; PMID: 15808399
   PubMed Web of Science ®Google Scholar
• Zhang Y-J, Chen Y, Ahsan H, Lunn RM, Lee PH, Chen CJ, et al. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relationship to aflatoxin B1-DNA adducts and p53 mutation in hepatocellular carcinoma. Int J Cancer 2003; 103:440 - 4; http://dx.doi.org/10.1002/ijc.10852; PMID: 12478658
   PubMed Web of Science ®Google Scholar
• Shen J, Wang S, Zhang YJ, Wu HC, Kibriya MG, Jasmine F, et al. Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips. Epigenetics 2013; 8:34 - 43; http://dx.doi.org/10.4161/epi.23062; PMID: 23208076
   PubMed Web of Science ®Google Scholar
• Lambert M-P, Paliwal A, Vaissière T, Chemin I, Zoulim F, Tommasino M, et al. Aberrant DNA methylation distinguishes hepatocellular carcinoma associated with HBV and HCV infection and alcohol intake. J Hepatol 2011; 54:705 - 15; http://dx.doi.org/10.1016/j.jhep.2010.07.027; PMID: 21146512
   PubMed Web of Science ®Google Scholar
• Hernandez-Vargas H, Lambert MP, Le Calvez-Kelm F, Gouysse G, McKay-Chopin S, Tavtigian SV, et al. Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors. PLoS One 2010; 5:e9749; http://dx.doi.org/10.1371/journal.pone.0009749; PMID: 20305825
   PubMed Web of Science ®Google Scholar
• Wilson AS, Power BE, Molloy PL. DNA hypomethylation and human diseases. Biochim Biophys Acta 2007; 1775:138 - 62; PMID: 17045745
   PubMed Web of Science ®Google Scholar
• Wu H-C, Wang Q, Yang H-I, Tsai W-Y, Chen C-J, Santella RM. Global DNA methylation levels in white blood cells as a biomarker for hepatocellular carcinoma risk: a nested case-control study. Carcinogenesis 2012; 33:1340 - 5; http://dx.doi.org/10.1093/carcin/bgs160; PMID: 22581841
   PubMed Web of Science ®Google Scholar
• Bailey EA, Iyer RS, Stone MP, Harris TM, Essigmann JM. Mutational properties of the primary aflatoxin B1-DNA adduct. Proc Natl Acad Sci U S A 1996; 93:1535 - 9; http://dx.doi.org/10.1073/pnas.93.4.1535; PMID: 8643667
   PubMed Web of Science ®Google Scholar
• Shen H-M, Ong C-N, Lee B-L, Shi C-Y. Aflatoxin B1-induced 8-hydroxydeoxyguanosine formation in rat hepatic DNA. Carcinogenesis 1995; 16:419 - 22; http://dx.doi.org/10.1093/carcin/16.2.419; PMID: 7859375
   PubMed Web of Science ®Google Scholar
• Shen H-M, Shi C-Y, Shen Y, Ong C-N. Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1. Free Radic Biol Med 1996; 21:139 - 46; http://dx.doi.org/10.1016/0891-5849(96)00019-6; PMID: 8818628
   PubMed Web of Science ®Google Scholar
• Wu H-C, Wang Q, Wang L-W, Yang HI, Ahsan H, Tsai WY, et al. Urinary 8-oxodeoxyguanosine, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in Taiwan. Carcinogenesis 2007; 28:995 - 9; http://dx.doi.org/10.1093/carcin/bgl234; PMID: 17127712
   PubMed Web of Science ®Google Scholar
• Wu H-C, Wang Q, Yang H-I, Ahsan H, Tsai WY, Wang LY, et al. Urinary 15-F2t-isoprostane, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in Taiwan. Carcinogenesis 2008; 29:971 - 6; http://dx.doi.org/10.1093/carcin/bgn057; PMID: 18310087
   PubMed Web of Science ®Google Scholar
• Turk PW, Laayoun A, Smith SS, Weitzman SA. DNA adduct 8-hydroxyl-2′-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase. Carcinogenesis 1995; 16:1253 - 5; http://dx.doi.org/10.1093/carcin/16.5.1253; PMID: 7767994
   PubMed Web of Science ®Google Scholar
• Valinluck V, Tsai H-H, Rogstad DK, Burdzy A, Bird A, Sowers LC. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res 2004; 32:4100 - 8; http://dx.doi.org/10.1093/nar/gkh739; PMID: 15302911
   PubMed Web of Science ®Google Scholar
• Pogribny IP, Tryndyak VP, Woods CG, Witt SE, Rusyn I. Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor α. Mutat Res 2007; 625:62 - 71; http://dx.doi.org/10.1016/j.mrfmmm.2007.05.004; PMID: 17586532
   PubMed Web of Science ®Google Scholar
• Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128:683 - 92; http://dx.doi.org/10.1016/j.cell.2007.01.029; PMID: 17320506
   PubMed Web of Science ®Google Scholar
• Lahiri DK. An integrated approach to genome studies. Science 2011; 331:147; http://dx.doi.org/10.1126/science.331.6014.147-a; PMID: 21233370
   PubMedGoogle Scholar
• Cooney CA, Dave AA, Wolff GL. Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring. J Nutr 2002; 132:Suppl 2393S - 400S; PMID: 12163699
   PubMed Web of Science ®Google Scholar
• Jousse C, Parry L, Lambert-Langlais S, Maurin AC, Averous J, Bruhat A, et al. Perinatal undernutrition affects the methylation and expression of the leptin gene in adults: implication for the understanding of metabolic syndrome. FASEB J 2011; 25:3271 - 8; http://dx.doi.org/10.1096/fj.11-181792; PMID: 21670064
   PubMed Web of Science ®Google Scholar
• Tobi EW, Lumey LH, Talens RP, Kremer D, Putter H, Stein AD, et al. DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum Mol Genet 2009; 18:4046 - 53; http://dx.doi.org/10.1093/hmg/ddp353; PMID: 19656776
   PubMed Web of Science ®Google Scholar
• Heijmans BT, Tobi EW, Stein AD, Putter H, Blauw GJ, Susser ES, et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc Natl Acad Sci U S A 2008; 105:17046 - 9; http://dx.doi.org/10.1073/pnas.0806560105; PMID: 18955703
   PubMed Web of Science ®Google Scholar
• Arasaradnam RP, Commane DM, Bradburn D, Mathers JC. A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis. Epigenetics 2008; 3:193 - 8; http://dx.doi.org/10.4161/epi.3.4.6508; PMID: 18682688
   PubMed Web of Science ®Google Scholar
• Mathers JC. Pulses and carcinogenesis: potential for the prevention of colon, breast and other cancers. Br J Nutr 2002; 88:Suppl 3 S273 - 9; http://dx.doi.org/10.1079/BJN2002717; PMID: 12498627
   PubMed Web of Science ®Google Scholar
• Shen L, Ahuja N, Shen Y, Habib NA, Toyota M, Rashid A, et al. DNA methylation and environmental exposures in human hepatocellular carcinoma. J Natl Cancer Inst 2002; 94:755 - 61; http://dx.doi.org/10.1093/jnci/94.10.755; PMID: 12011226
   PubMed Web of Science ®Google Scholar
• Feng Y, Xue W, Li P, et al. RASSF1A Hypermethylation is Associated with Aflatioxin B1 and Polycyclic Aromatic Hydrocarbon Exposure in Hepatocellular Carcinoma. Hepatogastroenterology 2011; 59:118 - 9
   Google Scholar
• Vivekanandan P, Daniel HD-J, Kannangai R, Martinez-Murillo F, Torbenson M, Hepatitis B. Hepatitis B virus replication induces methylation of both host and viral DNA. J Virol 2010; 84:4321 - 9; http://dx.doi.org/10.1128/JVI.02280-09; PMID: 20147412
   PubMed Web of Science ®Google Scholar
• Yeh SH, Chen PJ. Gender disparity of hepatocellular carcinoma: the roles of sex hormones. Oncology 2010; 78:Suppl 1 172 - 9; http://dx.doi.org/10.1159/000315247; PMID: 20616601
   PubMedGoogle Scholar
• Terry MB, Delgado-Cruzata L, Vin-Raviv N, Wu HC, Santella RM. DNA methylation in white blood cells: association with risk factors in epidemiologic studies. Epigenetics 2011; 6:828 - 37; http://dx.doi.org/10.4161/epi.6.7.16500; PMID: 21636973
   PubMed Web of Science ®Google Scholar
• Makarananda K, Pengpan U, Srisakulthong M, Yoovathaworn K, Sriwatanakul K. Monitoring of aflatoxin exposure by biomarkers. J Toxicol Sci 1998; 23:Suppl 2 155 - 9; http://dx.doi.org/10.2131/jts.23.SupplementII_155; PMID: 9760454
   PubMedGoogle Scholar
• Scholl PF, Groopman JD. Long-term stability of human aflatoxin B1 albumin adducts assessed by isotope dilution mass spectrometry and high-performance liquid chromatography-fluorescence. Cancer Epidemiol Biomarkers Prev 2008; 17:1436 - 9; http://dx.doi.org/10.1158/1055-9965.EPI-07-2926; PMID: 18559559
   PubMed Web of Science ®Google Scholar
• Gan L-S, Skipper PL, Peng XC, Groopman JD, Chen JS, Wogan GN, et al. Serum albumin adducts in the molecular epidemiology of aflatoxin carcinogenesis: correlation with aflatoxin B1 intake and urinary excretion of aflatoxin M1. Carcinogenesis 1988; 9:1323 - 5; http://dx.doi.org/10.1093/carcin/9.7.1323; PMID: 3133131
   PubMed Web of Science ®Google Scholar
• Zhu JQ, Zhang LS, Hu X, Xiao Y, Chen JS, Xu YC, et al. Correlation of dietary aflatoxin B1 levels with excretion of aflatoxin M1 in human urine. Cancer Res 1987; 47:1848 - 52; PMID: 3102051
   PubMed Web of Science ®Google Scholar
• Ahsan H, Wang L-Y, Chen C-J, Tsai W-Y, Santella RM. Variability in aflatoxin-albumin adduct levels and effects of hepatitis B and C virus infection and glutathione S-transferase M1 and T1 genotype. Environ Health Perspect 2001; 109:833 - 7; http://dx.doi.org/10.1289/ehp.01109833; PMID: 11564620
   PubMed Web of Science ®Google Scholar
• Wu H-C, Wang Q, Delgado-Cruzata L, Santella RM, Terry MB. Genomic methylation changes over time in peripheral blood mononuclear cell DNA: differences by assay type and baseline values. Cancer Epidemiol Biomarkers Prev 2012; 21:1314 - 8; http://dx.doi.org/10.1158/1055-9965.EPI-12-0300; PMID: 22665578
   PubMed Web of Science ®Google Scholar
• Reinius LE, Acevedo N, Joerink M, Pershagen G, Dahlén SE, Greco D, et al. Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility. PLoS One 2012; 7:e41361; http://dx.doi.org/10.1371/journal.pone.0041361; PMID: 22848472
   PubMed Web of Science ®Google Scholar
• Deaton AM, Webb S, Kerr ARW, Illingworth RS, Guy J, Andrews R, et al. Cell type-specific DNA methylation at intragenic CpG islands in the immune system. Genome Res 2011; 21:1074 - 86; http://dx.doi.org/10.1101/gr.118703.110; PMID: 21628449
   PubMed Web of Science ®Google Scholar
• Wu H-C, Delgado-Cruzata L, Flom JD, Kappil M, Ferris JS, Liao Y, et al. Global methylation profiles in DNA from different blood cell types. Epigenetics 2011; 6:76 - 85; http://dx.doi.org/10.4161/epi.6.1.13391; PMID: 20890131
   PubMed Web of Science ®Google Scholar
• Hinton DM, Myers MJ, Raybourne RA, Francke-Carroll S, Sotomayor RE, Shaddock J, et al. Immunotoxicity of aflatoxin B1 in rats: effects on lymphocytes and the inflammatory response in a chronic intermittent dosing study. Toxicol Sci 2003; 73:362 - 77; http://dx.doi.org/10.1093/toxsci/kfg074; PMID: 12700391
   PubMed Web of Science ®Google Scholar
• Hatch MC, Chen C-J, Levin B, Ji BT, Yang GY, Hsu SW, et al. Urinary aflatoxin levels, hepatitis-B virus infection and hepatocellular carcinoma in Taiwan. Int J Cancer 1993; 54:931 - 4; http://dx.doi.org/10.1002/ijc.2910540611; PMID: 8392983
   PubMed Web of Science ®Google Scholar
• Weisenberger DJ, Campan M, Long TI, Kim M, Woods C, Fiala E, et al. Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res 2005; 33:6823 - 36; http://dx.doi.org/10.1093/nar/gki987; PMID: 16326863
   PubMed Web of Science ®Google Scholar
• Yang AS, Estécio MRH, Doshi K, Kondo Y, Tajara EH, Issa JPJ. A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res 2004; 32:e38; http://dx.doi.org/10.1093/nar/gnh032; PMID: 14973332
   PubMed Web of Science ®Google Scholar