Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome

References

• Kim VN, Han J, Siomi MC. Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol 2009; 10:126 - 139
   PubMed Web of Science ®Google Scholar
• Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120:15 - 20
   PubMed Web of Science ®Google Scholar
• Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 2007; 27:91 - 105
   PubMed Web of Science ®Google Scholar
• Lim LP, Lau N, Garrett-Engele P, Grimson A, Schelter JM, Castle J, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005; 433:769 - 773
   PubMed Web of Science ®Google Scholar
• Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell 2003; 115:787 - 798
   PubMed Web of Science ®Google Scholar
• Lytle JR, Yario TA, Steitz JA. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR. Proc Natl Acad Sci USA 2007; 104:9667 - 9672
   PubMed Web of Science ®Google Scholar
• Jopling CL, Schutz S, Sarnow P. Position-dependent function for a tandem microRNA miR-122-binding site located in the hepatitis C virus RNA genome. Cell Host Microbe 2008; 4:77 - 85
   PubMed Web of Science ®Google Scholar
• Orom UA, Nielsen FC, Lund AH. MicroRNA-10a binds the 5′UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell 2008; 30:460 - 471
   PubMed Web of Science ®Google Scholar
• Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?. Nat Rev Genet 2008; 9:102 - 114
   PubMed Web of Science ®Google Scholar
• Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: microRNAs can upregulate translation. Science 2007; 318:1931 - 1934
   PubMed Web of Science ®Google Scholar
• Stefani G, Slack FJ. Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol 2008; 9:219 - 230
   PubMed Web of Science ®Google Scholar
• Yekta S, Tabin CJ, Bartel DP. MicroRNAs in the Hox network: an apparent link to posterior prevalence. Nat Rev Genet 2008; 9:789 - 796
   PubMed Web of Science ®Google Scholar
• Calin GA, Croce CM. MicroRNA-cancer connection: the beginning of a new tale. Cancer Res 2006; 66:7390 - 7394
   PubMed Web of Science ®Google Scholar
• Xiao C, Rajewsky K. MicroRNA control in the immune system: basic principles. Cell 2009; 136:26 - 36
   PubMed Web of Science ®Google Scholar
• Sethupathy P, Collins FS. MicroRNA target site polymorphisms and human disease. Trends Genet 2008; 24:489 - 497
   PubMed Web of Science ®Google Scholar
• Kosik KS. The neuronal microRNA system. Nat Rev Neurosci 2006; 7:911 - 920
   PubMed Web of Science ®Google Scholar
• Urdinguio RG, Sanchez-Mut JV, Esteller M. Epigenetic mechanisms in neurological diseases: genes, syndromes and therapies. Lancet Neurol 2009; 11:1056 - 1072
   Google Scholar
• Kim J, Inoue K, Ishii J, Vanti WB, Voronov SV, Murchison E, et al. A MicroRNA feedback circuit in midbrain dopamine neurons. Science 2007; 317:1220 - 1224
   PubMed Web of Science ®Google Scholar
• Schaefer A, O'Carroll D, Tan CL, Hillman D, Sugimori M, Llinas R, et al. Cerebellar neurodegeneration in the absence of microRNAs. J Exp Med 2007; 204:1553 - 1558
   PubMed Web of Science ®Google Scholar
• Davis TH, Cuellar TL, Koch SM, Barker AJ, Harfe BD, McManus MT, et al. Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci 2008; 28:4322 - 4330
   PubMed Web of Science ®Google Scholar
• Esteller M. Epigenetics in cancer. N Engl J Med 2008; 358:1148 - 1159
   PubMed Web of Science ®Google Scholar
• Davalos V, Esteller M. MicroRNAs and cancer epigenetics: a macrorevolution. Curr Opin Oncol 2010; 22:35 - 45
   PubMed Web of Science ®Google Scholar
• Bienvenu T, Chelly J. Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized. Nat Rev Genet 2006; 7:415 - 426
   PubMed Web of Science ®Google Scholar
• Klose RJ, Bird AP. Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 2006; 31:89 - 97
   PubMed Web of Science ®Google Scholar
• Lopez-Serra L, Esteller M. Proteins that bind methylated DNA and human cancer: reading the wrong words. Br J Cancer 2008; 98:1881 - 1885
   PubMed Web of Science ®Google Scholar
• Hendrich B, Bird A. Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol Cell Biol 1998; 18:6538 - 6547
   PubMed Web of Science ®Google Scholar
• Hendrich B, Tweedie S. The methyl-CpG binding domain and the evolving role of DNA methylation in animals. Trends Genet 2003; 19:269 - 277
   PubMed Web of Science ®Google Scholar
• Dhasarathy A, Wade PA. The MBD protein family-reading an epigenetic mark?. Mutat Res 2008; 647:39 - 43
   PubMed Web of Science ®Google Scholar
• Ballestar E, Paz MF, Valle L, Wei S, Fraga MF, Espada J, et al. Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer. EMBO J 2003; 22:6335 - 6345
   PubMed Web of Science ®Google Scholar
• Lopez-Serra L, Ballestar E, Fraga MF, Alaminos M, Setien F, Esteller M. A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer. Cancer Res 2006; 66:8342 - 8346
   PubMed Web of Science ®Google Scholar
• Lopez-Serra L, Ballestar E, Ropero S, Setien F, Billard LM, Fraga MF, et al. Unmasking of epigenetically silenced candidate tumor suppressor genes by removal of methyl-CpG-binding domain proteins. Oncogene 2008; 27:3556 - 3566
   PubMed Web of Science ®Google Scholar
• Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA, et al. Specific activation of microRNA-127 with downregulation of the protooncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006; 9:435 - 443
   PubMed Web of Science ®Google Scholar
• Lujambio A, Ropero S, Ballestar E, Fraga MF, Cerrato C, Setien F, et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res 2007; 67:1424 - 1429
   PubMed Web of Science ®Google Scholar
• Lujambio A, Calin GA, Villanueva A, Ropero S, Sánchez-Céspedes M, Blanco D, et al. A microRNA DNA methylation signature for human cancer metastasis. Proc Natl Acad Sci USA 2008; 105:13556 - 13561
   PubMed Web of Science ®Google Scholar
• Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, et al. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res 2008; 68:4123 - 4132
   PubMed Web of Science ®Google Scholar
• Huang YW, Liu JC, Deatherage DE, Luo J, Mutch DG, Goodfellow PJ, et al. Epigenetic repression of microRNA-129-2 leads to overexpression of SOX4 oncogene in endometrial cancer. Cancer Res 2009; 69:9038 - 9046
   PubMed Web of Science ®Google Scholar
• Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 1999; 23:185 - 188
   PubMed Web of Science ®Google Scholar
• Zoghbi HY. Mecp2 dysfunction in humans and mice. J Child Neurol 2005; 20:736 - 740
   PubMed Web of Science ®Google Scholar
• Neul JL, Zoghbi HY. Rett syndrome: a prototypical neurodevelopmental disorder. Neuroscientist 2004; 10:118 - 128
   PubMed Web of Science ®Google Scholar
• Guy J, Hendrich B, Holmes M, Martin JE, Bird A. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 2001; 27:322 - 326
   PubMed Web of Science ®Google Scholar
• Liu CG, Calin GA, Meloon B, Gamliel N, Sevignani C, Ferracin M, et al. An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues. Proc Natl Acad Sci USA 2004; 101:9740 - 9744
   PubMed Web of Science ®Google Scholar
• Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J, Zoghbi HY. Mecp2, a key contributor to neurological disease, activates and represses transcription. Science 2008; 320:1224 - 1229
   PubMed Web of Science ®Google Scholar
• Ballestar E, Ropero S, Alaminos M, Armstrong J, Setien F, Agrelo R, et al. The impact of MECP2 mutations in the expression patterns of Rett syndrome patients. Hum Genet 2005; 116:91 - 104
   PubMed Web of Science ®Google Scholar
• Fraga MF, Ballestar E, Montoya G, Taysavang P, Wade PA, Esteller M. The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties. Nucleic Acids Res 2003; 31:1765 - 1774
   PubMed Web of Science ®Google Scholar
• Jiao J, Herl LD, Farese RV, Gao FB. microRNA-29b regulates the expression level of human progranulin, a secreted glycoprotein implicated in frontotemporal dementia. PLoS One 2010; 5:10551
   PubMed Web of Science ®Google Scholar
• Xia H, Qi Y, Ng SS, Chen X, Li D, Chen S, et al. microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs. Brain Res 2009; 1269:158 - 165
   PubMed Web of Science ®Google Scholar
• Hebert SS, Horre K, Nicolai L, Papadopoulou AS, Mandemakers W, Silahtaroglu AN, et al. Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci USA 2008; 5:6415 - 6420
   Web of Science ®Google Scholar
• Taganov KD, Boldin MP, Chang KJ, Baltimore D. NFkappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 2006; 103:12481 - 12486
   PubMed Web of Science ®Google Scholar
• Urdinguio RG, Lopez-Serra L, Lopez-Nieva P, Alaminos M, Diaz-Uriarte R, Fernandez AF, et al. Mecp2-null mice provide new neuronal targets for Rett syndrome. PLoS ONE 2008; 3:3669
   PubMed Web of Science ®Google Scholar
• Su J, Richter K, Zhang C, Gu Q, Li L. Differential regulation of interleukin-1 receptor associated kinase 1 (IRAK1) splice variants. Mol Immunol 2007; 44:900 - 905
   PubMed Web of Science ®Google Scholar
• Miralves J, Magdeleine E, Joly E. Design of an improved set of oligonucleotide primers for genotyping Mecp2tm1.1Bird KO mice by PCR. Mol Neurodegener 2007; 2:16
   PubMed Web of Science ®Google Scholar
• Raymond CK, Roberts BS, Garrett-Engele P, Lim LP, Johnson JM. Simple, quantitative primer-extension PCR assay for direct monitoring of microRNAs and short-interfering RNAs. RNA 2005; 11:1737 - 1744
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25:402 - 408
   PubMed Web of Science ®Google Scholar
• Deng V, Matagne V, Banine F, Frerking M, Ohliger P, Budden S, et al. FXYD1 is an Mecp2 target gene overexpressed in the brains of Rett syndrome patients and Mecp2-null mice. Hum Mol Genet 2007; 16:640 - 650
   PubMed Web of Science ®Google Scholar
• Zhou X, Ruan J, Wang G, Zhang W. Characterization and identification of microRNA core promoters in four model species. PLoS Comput Biol 2007; 3:37
   PubMed Web of Science ®Google Scholar
• Takai D, Jones PA. The CpG island searcher: a new WWW resource. In Silico Biol 2003; 3:235 - 240
   PubMedGoogle Scholar
• Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996; 93:9821 - 9826
   PubMed Web of Science ®Google Scholar