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Research Paper

Monozygotic twins discordant for constitutive BRCA1 promoter methylation, childhood cancer and secondary cancer

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Pages 47-54 | Received 02 Sep 2011, Accepted 21 Nov 2011, Published online: 01 Jan 2012

References

  • Kramárová E, Stiller CA. The international classification of childhood cancer. Int J Cancer 1996; 68:759 - 65; http://dx.doi.org/10.1002/(SICI)1097-0215(19961211)68:6<759::AID-IJC12>3.0.CO;2-W; PMID: 8980180
  • Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcinogenesis 2010; 31:27 - 36; http://dx.doi.org/10.1093/carcin/bgp220; PMID: 19752007
  • Tsai HC, Baylin SB. Cancer epigenetics: linking basic biology to clinical medicine. Cell Res 2011; 21:502 - 17; http://dx.doi.org/10.1038/cr.2011.24; PMID: 21321605
  • Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003; 33:Suppl 245 - 54; http://dx.doi.org/10.1038/ng1089; PMID: 12610534
  • Weber M, Hellmann I, Stadler MB, Ramos L, Pääbo S, Rebhan M, et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007; 39:457 - 66; http://dx.doi.org/10.1038/ng1990; PMID: 17334365
  • Catteau A, Harris WH, Xu CF, Solomon E. Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics. Oncogene 1999; 18:1957 - 65; http://dx.doi.org/10.1038/sj.onc.1202509; PMID: 10208417
  • Bianco T, Chenevix-Trench G, Walsh DC, Cooper JE, Dobrovic A. Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer. Carcinogenesis 2000; 21:147 - 51; http://dx.doi.org/10.1093/carcin/21.2.147; PMID: 10657950
  • Esteller M, Silva JM, Dominguez G, Bonilla F, Matias-Guiu X, Lerma E, et al. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst 2000; 92:564 - 9; http://dx.doi.org/10.1093/jnci/92.7.564; PMID: 10749912
  • Tost J, Dunker J, Gut IG. Analysis and quantification of multiple methylation variable positions in CpG islands by pyrosequencing. Biotechniques 2003; 35:152 - 6; PMID: 12866415
  • Sontag LB, Lorincz MC, Georg Luebeck E. Dynamics, stability and inheritance of somatic DNA methylation imprints. J Theor Biol 2006; 242:890 - 9; http://dx.doi.org/10.1016/j.jtbi.2006.05.012; PMID: 16806276
  • Raval A, Tanner SM, Byrd JC, Angerman EB, Perko JD, Chen SS, et al. Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia. Cell 2007; 129:879 - 90; http://dx.doi.org/10.1016/j.cell.2007.03.043; PMID: 17540169
  • Ligtenberg MJ, Kuiper RP, Chan TL, Goossens M, Hebeda KM, Voorendt M, et al. Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1. Nat Genet 2009; 41:112 - 7; http://dx.doi.org/10.1038/ng.283; PMID: 19098912
  • Hitchins MP, Rapkins RW, Kwok CT, Srivastava S, Wong JJ, Khachigian LM, et al. Dominantly inherited constitutional epigenetic silencing of MLH1 in a cancer-affected family is linked to a single nucleotide variant within the 5′UTR. Cancer Cell 2011; 20:200 - 13; http://dx.doi.org/10.1016/j.ccr.2011.07.003; PMID: 21840485
  • Wild PS, Sinning CR, Roth A, Wilde S, Schnabel RB, Lubos E, et al. Distribution and categorization of left ventricular measurements in the general population: results from the population-based Gutenberg Heart Study. Circ Cardiovasc Imaging 2010; 3:604 - 13; http://dx.doi.org/10.1161/CIRCIMAGING.109.911933; PMID: 20643817
  • Bruder CE, Piotrowski A, Gijsbers AA, Andersson R, Erickson S, Diaz de Ståhl T, et al. Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles. Am J Hum Genet 2008; 82:763 - 71; http://dx.doi.org/10.1016/j.ajhg.2007.12.011; PMID: 18304490
  • Kimani JW, Yoshiura K, Shi M, Jugessur A, Moretti-Ferreira D, Christensen K, et al. Search for genomic alterations in monozygotic twins discordant for cleft lip and/or palate. Twin Res Hum Genet 2009; 12:462 - 8; http://dx.doi.org/10.1375/twin.12.5.462; PMID: 19803774
  • Baranzini SE, Mudge J, van Velkinburgh JC, Khankhanian P, Khrebtukova I, Miller NA, et al. Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature 2010; 464:1351 - 6; http://dx.doi.org/10.1038/nature08990; PMID: 20428171
  • Fraga MF, Ballestar E, Paz MF, Ropero S, Setien F, Ballestar ML, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci USA 2005; 102:10604 - 9; http://dx.doi.org/10.1073/pnas.0500398102; PMID: 16009939
  • Kaminsky ZA, Tang T, Wang SC, Ptak C, Oh GH, Wong AH, et al. DNA methylation profiles in monozygotic and dizygotic twins. Nat Genet 2009; 41:240 - 5; http://dx.doi.org/10.1038/ng.286; PMID: 19151718
  • Bennett-Baker PE, Wilkowski J, Burke DT. Age-associated activation of epigenetically repressed genes in the mouse. Genetics 2003; 165:2055 - 62; PMID: 14704185
  • Goyal R, Reinhardt R, Jeltsch A. Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase. Nucleic Acids Res 2006; 34:1182 - 8; http://dx.doi.org/10.1093/nar/gkl002; PMID: 16500889
  • Sutherland JE, Costa M. Epigenetics and the environment. Ann N Y Acad Sci 2003; 983:151 - 60; http://dx.doi.org/10.1111/j.1749-6632.2003.tb05970.x; PMID: 12724220
  • Whitelaw NC, Whitelaw E. How lifetimes shape epigenotype within and across generations. Hum Mol Genet 2006; 15:R131 - 7; http://dx.doi.org/10.1093/hmg/ddl200; PMID: 16987876
  • Dolinoy DC, Jirtle RL. Environmental epigenomics in human health and disease. Environ Mol Mutagen 2008; 49:4 - 8; http://dx.doi.org/10.1002/em.20366; PMID: 18172876
  • Studler JM, Glowinski J, Levi-Strauss M. An abundant mRNA of the embryonic brain persists at a high level in cerebellum, hippocampus and olfactory bulb during adulthood. Eur J Neurosci 1993; 5:614 - 23; http://dx.doi.org/10.1111/j.1460-9568.1993.tb00527.x; PMID: 8261136
  • Kim KA, Zhao J, Andarmani S, Kakitani M, Oshima T, Binnerts ME, et al. R-Spondin proteins: a novel link to beta-catenin activation. Cell Cycle 2006; 5:23 - 6; http://dx.doi.org/10.4161/cc.5.1.2305; PMID: 16357527
  • Theodorou V, Kimm MA, Boer M, Wessels L, Theelen W, Jonkers J, et al. MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer. Nat Genet 2007; 39:759 - 69; http://dx.doi.org/10.1038/ng2034; PMID: 17468756
  • Brooks GA, Stopfer JE, Erlichman J, Davidson R, Nathanson KL, Domchek SM. Childhood cancer in families with and without BRCA1 or BRCA2 mutations ascertained at a high-risk breast cancer clinic. Cancer Biol Ther 2006; 5:1098 - 102; http://dx.doi.org/10.4161/cbt.5.9.3167; PMID: 16931905
  • Deutsch E, Jarrousse S, Buet D, Dugray A, Bonnet ML, Vozenin-Brotons MC, et al. Downregulation of BRCA1 in BCR-ABL-expressing hematopoietic cells. Blood 2003; 101:4583 - 8; http://dx.doi.org/10.1182/blood-2002-10-3011; PMID: 12576338
  • Scardocci A, Guidi F, D'Alo' F, Gumiero D, Fabiani E, Diruscio A, et al. Reduced BRCA1 expression due to promoter hypermethylation in therapy-related acute myeloid leukaemia. Br J Cancer 2006; 95:1108 - 13; http://dx.doi.org/10.1038/sj.bjc.6603392; PMID: 17047656
  • Esteller M, Corn PG, Baylin SB, Herman JG. A gene hypermethylation profile of human cancer. Cancer Res 2001; 61:3225 - 9; PMID: 11309270
  • Reik W, Dean W, Walter J. Epigenetic reprogramming in mammalian development. Science 2001; 293:1089 - 93; http://dx.doi.org/10.1126/science.1063443; PMID: 11498579
  • Haaf T. Methylation dynamics in the early mammalian embryo: implications of genome reprogramming defects for development. Curr Top Microbiol Immunol 2006; 310:13 - 22; http://dx.doi.org/10.1007/3-540-31181-5_2; PMID: 16909904
  • Schneider E, Pliushch G, El Hajj N, Galetzka D, Puhl A, Schorsch M, et al. Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns. Nucleic Acids Res 2010; 38:3880 - 90; http://dx.doi.org/10.1093/nar/gkq126; PMID: 20194112
  • Weksberg R, Shuman C, Caluseriu O, Smith AC, Fei YL, Nishikawa J, et al. Discordant KCNQ1OT1 imprinting in sets of monozygotic twins discordant for Beckwith-Wiedemann syndrome. Hum Mol Genet 2002; 11:1317 - 25; http://dx.doi.org/10.1093/hmg/11.11.1317; PMID: 12019213
  • Scott RH, Douglas J, Baskcomb L, Huxter N, Barker K, Hanks S, et al. Constitutional 11p15 abnormalities, including heritable imprinting center mutations, cause nonsyndromic Wilms tumor. Nat Genet 2008; 40:1329 - 34; http://dx.doi.org/10.1038/ng.243; PMID: 18836444
  • Lohmann DR, Gerick M, Brandt B, Oelschlager U, Lorenz B, Passarge E, et al. Constitutional RB1-gene mutations in patients with isolated unilateral retinoblastoma. Am J Hum Genet 1997; 61:282 - 94; http://dx.doi.org/10.1086/514845; PMID: 9311732
  • Youssoufian H, Pyeritz RE. Mechanisms and consequences of somatic mosaicism in humans. Nat Rev Genet 2002; 3:748 - 58; http://dx.doi.org/10.1038/nrg906; PMID: 12360233
  • Erickson RP. Somatic gene mutation and human disease other than cancer. Mutat Res 2003; 543:125 - 36; http://dx.doi.org/10.1016/S1383-5742(03)00010-3; PMID: 12644182
  • Hitchins MP, Ward RL. Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer. J Med Genet 2009; 46:793 - 802; http://dx.doi.org/10.1136/jmg.2009.068122; PMID: 19564652
  • Maunakea AK, Nagarajan RP, Bilenky M, Ballinger TJ, D'Souza C, Fouse SD, et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature 2010; 466:253 - 7; http://dx.doi.org/10.1038/nature09165; PMID: 20613842
  • Kitagawa R, Kastan MB. The ATM-dependent DNA damage signaling pathway. Cold Spring Harb Symp Quant Biol 2005; 70:99 - 109; http://dx.doi.org/10.1101/sqb.2005.70.002; PMID: 16869743
  • Snell C, Krypuy M, Wong EM. kConFab investigators, Loughrey MB, Dobrovic A. BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotype. Breast Cancer Res 2008; 10:R12; http://dx.doi.org/10.1186/bcr1858; PMID: 18269736
  • Al-Moghrabi N, Al-Qasem AJ, Aboussekhra A. Methylation-related mutations in the BRCA1 promoter in peripheral blood cells from cancer-free women. Int J Oncol 2011; 39:129 - 35; PMID: 21537840
  • El Hajj N, Trapphoff T, Linke M, May A, Hansmann T, Kuhtz J, et al. Limiting dilution bisulfite (pyro)sequencing reveals parent-specific methylation patterns in single oocytes and early embryos. Epigenetics 2011; 6:1176 - 88; PMID: 21937882
  • Bock C, Reither S, Mikeska T, Paulsen M, Walter J, Lengauer T. BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinformatics 2005; 21:4067 - 8; http://dx.doi.org/10.1093/bioinformatics/bti652; PMID: 16141249
  • Cheadle C, Vawter MP, Freed WJ, Becker KG. Analysis of microarray data using Z score transformation. J Mol Diagn 2003; 5:73 - 81; http://dx.doi.org/10.1016/S1525-1578(10)60455-2; PMID: 12707371