1,265
Views
11
CrossRef citations to date
0
Altmetric
Research Paper

Construction and screening of attenuated ΔphoP/Q Salmonella typhimurium vectored plague vaccine candidates

, , , , &
Pages 371-383 | Published online: 13 Feb 2012

References

  • Inglesby TV, Dennis DT, Henderson DA, Bartlett JG, Ascher MS, Eitzen E, et al, Working Group on Civilian Biodefense. Plague as a biological weapon: medical and public health management. JAMA 2000; 283:2281 - 90; http://dx.doi.org/10.1001/jama.283.17.2281; PMID: 10807389
  • Knight J. Delivering death in the mail. Nature 2001; 414:837 - 8; http://dx.doi.org/10.1038/414837a; PMID: 11780023
  • Kotton CN, Hohmann EL. Enteric pathogens as vaccine vectors for foreign antigen delivery. Infect Immun 2004; 72:5535 - 47; http://dx.doi.org/10.1128/IAI.72.10.5535-5547.2004; PMID: 15385450
  • Galen JE, Pasetti MF, Tennant S, Ruiz-Olvera P, Sztein MB, Levine MM. Salmonella enterica serovar Typhi live vector vaccines finally come of age. Immunol Cell Biol 2009; 87:400 - 12; http://dx.doi.org/10.1038/icb.2009.31; PMID: 19417771
  • Atkins HS, Morton M, Griffin KF, Stokes MG, Nataro JP, Titball RW. Recombinant Salmonella vaccines for biodefence. Vaccine 2006; 24:2710 - 7; http://dx.doi.org/10.1016/j.vaccine.2005.12.046; PMID: 16434131
  • Li B, Jiang L, Song Q, Yang J, Chen Z, Guo Z, et al. Protein microarray for profiling antibody responses to Yersinia pestis live vaccine. Infect Immun 2005; 73:3734 - 9; http://dx.doi.org/10.1128/IAI.73.6.3734-3739.2005; PMID: 15908403
  • Alvarez ML, Pinyerd HL, Crisantes JD, Rigano MM, Pinkhasov J, Walmsley AM, et al. Plant-made subunit vaccine against pneumonic and bubonic plague is orally immunogenic in mice. Vaccine 2006; 24:2477 - 90; http://dx.doi.org/10.1016/j.vaccine.2005.12.057; PMID: 16442673
  • Jones T, Adamovicz JJ, Cyr SL, Bolt CR, Bellerose N, Pitt LM, et al. Intranasal Protollin/F1-V vaccine elicits respiratory and serum antibody responses and protects mice against lethal aerosolized plague infection. Vaccine 2006; 24:1625 - 32; http://dx.doi.org/10.1016/j.vaccine.2005.09.052; PMID: 16243411
  • Santi L, Giritch A, Roy CJ, Marillonnet S, Klimyuk V, Gleba Y, et al. Protection conferred by recombinant Yersinia pestis antigens produced by a rapid and highly scalable plant expression system. Proc Natl Acad Sci U S A 2006; 103:861 - 6; http://dx.doi.org/10.1073/pnas.0510014103; PMID: 16410352
  • Eyles JE, Elvin SJ, Westwood A, Lebutt CS, Alpar HO, Somavarapu S, et al. Immunisation against plague by transcutaneous and intradermal application of subunit antigens. Vaccine 2004; 22:4365 - 73; http://dx.doi.org/10.1016/j.vaccine.2004.02.049; PMID: 15474730
  • Glynn A, Freytag LC, Clements JD. Effect of homologous and heterologous prime-boost on the immune response to recombinant plague antigens. Vaccine 2005; 23:1957 - 65; http://dx.doi.org/10.1016/j.vaccine.2004.10.025; PMID: 15734068
  • Glynn A, Roy CJ, Powell BS, Adamovicz JJ, Freytag LC, Clements JD. Protection against aerosolized Yersinia pestis challenge following homologous and heterologous prime-boost with recombinant plague antigens. Infect Immun 2005; 73:5256 - 61; http://dx.doi.org/10.1128/IAI.73.8.5256-5261.2005; PMID: 16041052
  • Kang HY, Srinivasan J, Curtiss R 3rd. Immune responses to recombinant pneumococcal PspA antigen delivered by live attenuated Salmonella enterica serovar typhimurium vaccine. Infect Immun 2002; 70:1739 - 49; http://dx.doi.org/10.1128/IAI.70.4.1739-1749.2002; PMID: 11895935
  • Gentschev I, Mollenkopf H, Sokolovic Z, Hess J, Kaufmann SH, Goebel W. Development of antigen-delivery systems, based on the Escherichia coli hemolysin secretion pathway. Gene 1996; 179:133 - 40; http://dx.doi.org/10.1016/S0378-1119(96)00424-6; PMID: 8955639
  • C´rdenas L, Clements JD. Oral immunization using live attenuated Salmonella spp. as carriers of foreign antigens. Clin Microbiol Rev 1992; 5:328 - 42; PMID: 1498769
  • Hohmann EL, Oletta CA, Killeen KP, Miller SI. phoP/phoQ-deleted Salmonella typhi (Ty800) is a safe and immunogenic single-dose typhoid fever vaccine in volunteers. J Infect Dis 1996; 173:1408 - 14; http://dx.doi.org/10.1093/infdis/173.6.1408; PMID: 8648213
  • Anonymous. (2008) AVANT's single-dose oral Ty800 vaccine meets primary endpoints in Phase 2 study, In Medical News Today.
  • Anderson GW Jr., Leary SE, Williamson ED, Titball RW, Welkos SL, Worsham PL, et al. Recombinant V antigen protects mice against pneumonic and bubonic plague caused by F1-capsule-positive and -negative strains of Yersinia pestis. Infect Immun 1996; 64:4580 - 5; PMID: 8890210
  • Calhoun LN, Kwon YM. Salmonella-based plague vaccines for bioterrorism. J Microbiol Immunol Infect 2006; 39:92 - 7; PMID: 16604240
  • Williamson ED, Stagg AJ, Eley SM, Taylor R, Green M, Jones SM, et al. Kinetics of the immune response to the (F1+V) vaccine in models of bubonic and pneumonic plague. Vaccine 2007; 25:1142 - 8; http://dx.doi.org/10.1016/j.vaccine.2006.09.052; PMID: 17101198
  • Yang X, Hinnebusch BJ, Trunkle T, Bosio CM, Suo Z, Tighe M, et al. Oral vaccination with salmonella simultaneously expressing Yersinia pestis F1 and V antigens protects against bubonic and pneumonic plague. J Immunol 2007; 178:1059 - 67; PMID: 17202369
  • Curtiss R 3rd, Xin W, Li Y, Kong W, Wanda SY, Gunn B, et al. New technologies in using recombinant attenuated Salmonella vaccine vectors. Crit Rev Immunol 2010; 30:255 - 70; PMID: 20370633
  • Morton M, Garmory HS, Perkins SD, O’Dowd AM, Griffin KF, Turner AK, et al. A Salmonella enterica serovar Typhi vaccine expressing Yersinia pestis F1 antigen on its surface provides protection against plague in mice. Vaccine 2004; 22:2524 - 32; http://dx.doi.org/10.1016/j.vaccine.2004.01.007; PMID: 15193377
  • Titball RW, Howells AM, Oyston PC, Williamson ED. Expression of the Yersinia pestis capsular antigen (F1 antigen) on the surface of an aroA mutant of Salmonella typhimurium induces high levels of protection against plague. Infect Immun 1997; 65:1926 - 30; PMID: 9125581
  • Garmory HS, Leckenby MW, Griffin KF, Elvin SJ, Taylor RR, Hartley MG, et al. Antibiotic-free plasmid stabilization by operator-repressor titration for vaccine delivery by using live Salmonella enterica Serovar typhimurium. Infect Immun 2005; 73:2005 - 11; http://dx.doi.org/10.1128/IAI.73.4.2005-2011.2005; PMID: 15784541
  • Spreng S, Dietrich G, Weidinger G. Rational design of Salmonella-based vaccination strategies. Methods 2006; 38:133 - 43; http://dx.doi.org/10.1016/j.ymeth.2005.09.012; PMID: 16414270
  • Ryan ET, Crean TI, Kochi SK, John M, Luciano AA, Killeen KP, et al. Development of a DeltaglnA balanced lethal plasmid system for expression of heterologous antigens by attenuated vaccine vector strains of Vibrio cholerae. Infect Immun 2000; 68:221 - 6; http://dx.doi.org/10.1128/IAI.68.1.221-226.2000; PMID: 10603391
  • Angelakopoulos H, Hohmann EL. Pilot study of phoP/phoQ-deleted Salmonella enterica serovar typhimurium expressing Helicobacter pylori urease in adult volunteers. Infect Immun 2000; 68:2135 - 41; http://dx.doi.org/10.1128/IAI.68.4.2135-2141.2000; PMID: 10722611
  • Nakayama K, Kelly SM, Curtiss R. Construction of an ASD+ Expression-Cloning Vector: Stable Maintenance and High Level Expression of Cloned Genes in a Salmonella Vaccine Strain. Nat Biotechnol 1988; 6:693 - 7; http://dx.doi.org/10.1038/nbt0688-693
  • Oyston PC, Williamson ED, Leary SE, Eley SM, Griffin KF, Titball RW. Immunization with live recombinant Salmonella typhimurium aroA producing F1 antigen protects against plague. Infect Immun 1995; 63:563 - 8; PMID: 7822022
  • Leary SE, Griffin KF, Garmory HS, Williamson ED, Titball RW. Expression of an F1/V fusion protein in attenuated Salmonella typhimurium and protection of mice against plague. Microb Pathog 1997; 23:167 - 79; http://dx.doi.org/10.1006/mpat.1997.0141; PMID: 9281474
  • Branger CG, Sun W, Torres-Escobar A, Perry R, Roland KL, Fetherston J, et al. Evaluation of Psn, HmuR and a modified LcrV protein delivered to mice by live attenuated Salmonella as a vaccine against bubonic and pneumonic Yersinia pestis challenge. Vaccine 2010; 29:274 - 82; http://dx.doi.org/10.1016/j.vaccine.2010.10.033; PMID: 20979987
  • Roland KL, Cloninger C, Kochi SK, Thomas LJ, Tinge SA, Rouskey C, et al. Construction and preclinical evaluation of recombinant Peru-15 expressing high levels of the cholera toxin B subunit as a vaccine against enterotoxigenic Escherichia coli. Vaccine 2007; 25:8574 - 84; http://dx.doi.org/10.1016/j.vaccine.2007.09.074; PMID: 18045752
  • Linnetz EG, Borrelli KM, Mazzolla AM, Ryan GS, Sikes KB, Kearney MA, et al. Optimization of a rabbit model of attenuated Vibrio cholerae immunogenicity. Contemporary Topics 2004; 43:58
  • Roland KL, Tinge SA, Kochi SK, Thomas LJ, Killeen KP. Reactogenicity and immunogenicity of live attenuated Salmonella enterica serovar Paratyphi A enteric fever vaccine candidates. Vaccine 2010; 28:3679 - 87; http://dx.doi.org/10.1016/j.vaccine.2010.03.019; PMID: 20338215
  • Bashaw J, Norris S, Weeks S, Trevino S, Adamovicz JJ, Welkos S. Development of in vitro correlate assays of immunity to infection with Yersinia pestis. Clin Vaccine Immunol 2007; 14:605 - 16; http://dx.doi.org/10.1128/CVI.00398-06; PMID: 17376861
  • Williamson ED, Flick-Smith HC, Waters E, Miller J, Hodgson I, Le Butt CS, et al. Immunogenicity of the rF1+rV vaccine for plague with identification of potential immune correlates. Microb Pathog 2007; 42:11 - 21; http://dx.doi.org/10.1016/j.micpath.2006.09.003; PMID: 17107769
  • Sizemore DR, Warner B, Lawrence J, Jones A, Killeen KP. Live, attenuated Salmonella typhimurium vectoring Campylobacter antigens. Vaccine 2006; 24:3793 - 803; http://dx.doi.org/10.1016/j.vaccine.2005.07.026; PMID: 16135393
  • Wai SN, Westermark M, Oscarsson J, Jass J, Maier E, Benz R, et al. Characterization of dominantly negative mutant ClyA cytotoxin proteins in Escherichia coli. J Bacteriol 2003; 185:5491 - 9; http://dx.doi.org/10.1128/JB.185.18.5491-5499.2003; PMID: 12949101
  • Carlone GM, Thomas ML, Rumschlag HS, Sottnek FO. Rapid microprocedure for isolating detergent-insoluble outer membrane proteins from Haemophilus species. J Clin Microbiol 1986; 24:330 - 2; PMID: 3489731

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.