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Research Paper

Characterization of the biological anti-staphylococcal functionality of hUK-66 IgG1, a humanized monoclonal antibody as substantial component for an immunotherapeutic approach

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Pages 926-937 | Received 26 Sep 2013, Accepted 31 Dec 2013, Published online: 04 Feb 2014

References

  • Sánchez García M. Early antibiotic treatment failure. Int J Antimicrob Agents 2009; 34:Suppl 3 S14 - 9; http://dx.doi.org/10.1016/S0924-8579(09)70552-7; PMID: 19596109
  • Rubinstein E, Kollef MH, Nathwani D. Pneumonia caused by methicillin-resistant Staphylococcus aureus. Clin Infect Dis 2008; 46:Suppl 5 S378 - 85; http://dx.doi.org/10.1086/533594; PMID: 18462093
  • Kollef MH, Morrow LE, Niederman MS, Leeper KV, Anzueto A, Benz-Scott L, Rodino FJ. Clinical characteristics and treatment patterns among patients with ventilator-associated pneumonia. Chest 2006; 129:1210 - 8; http://dx.doi.org/10.1378/chest.129.5.1210; PMID: 16685011
  • Verkaik NJ, van Wamel WJ, van Belkum A. Immunotherapeutic approaches against Staphylococcus aureus.. Immunotherapy 2011; 3:1063 - 73; http://dx.doi.org/10.2217/imt.11.84; PMID: 21913829
  • Jansen KU, Girgenti DQ, Scully IL, Anderson AS. Vaccine review: “Staphyloccocus aureus vaccines: problems and prospects”. Vaccine 2013; 31:2723 - 30; http://dx.doi.org/10.1016/j.vaccine.2013.04.002; PMID: 23624095
  • Adhikari RP, Ajao AO, Aman MJ, Karauzum H, Sarwar J, Lydecker AD, Johnson JK, Nguyen C, Chen WH, Roghmann MC. Lower antibody levels to Staphylococcus aureus exotoxins are associated with sepsis in hospitalized adults with invasive S. aureus infections. J Infect Dis 2012; 206:915 - 23; http://dx.doi.org/10.1093/infdis/jis462; PMID: 22807524
  • van der Kooi-Pol MM, de Vogel CP, Westerhout-Pluister GN, Veenstra-Kyuchukova YK, Duipmans JC, Glasner C, Buist G, Elsinga GS, Westra H, Bonarius HP, et al. High anti-staphylococcal antibody titers in patients with epidermolysis bullosa relate to long-term colonization with alternating types of Staphylococcus aureus.. J Invest Dermatol 2013; 133:847 - 50; http://dx.doi.org/10.1038/jid.2012.347; PMID: 23014336
  • Bagnoli F, Bertholet S, Grandi G. Inferring reasons for the failure of Staphylococcus aureus vaccines in clinical trials. Front Cell Infect Microbiol 2012; 2:16; http://dx.doi.org/10.3389/fcimb.2012.00016; PMID: 22919608
  • Lorenz U, Lorenz B, Schmitter T, Streker K, Erck C, Wehland J, Nickel J, Zimmermann B, Ohlsen K. Functional antibodies targeting IsaA of Staphylococcus aureus augment host immune response and open new perspectives for antibacterial therapy. Antimicrob Agents Chemother 2011; 55:165 - 73; http://dx.doi.org/10.1128/AAC.01144-10; PMID: 20956605
  • Lorenz U, Ohlsen K, Karch H, Hecker M, Thiede A, Hacker J. Human antibody response during sepsis against targets expressed by methicillin resistant Staphylococcus aureus.. FEMS Immunol Med Microbiol 2000; 29:145 - 53; http://dx.doi.org/10.1111/j.1574-695X.2000.tb01517.x; PMID: 11024354
  • Sakata N, Mukai T. Production profile of the soluble lytic transglycosylase homologue in Staphylococcus aureus during bacterial proliferation. FEMS Immunol Med Microbiol 2007; 49:288 - 95; http://dx.doi.org/10.1111/j.1574-695X.2006.00200.x; PMID: 17328763
  • den Reijer PM, Lemmens-den Toom N, Kant S, Snijders SV, Boelens H, Tavakol M, Verkaik NJ, van Belkum A, Verbrugh HA, van Wamel WJ. Characterization of the humoral immune response during Staphylococcus aureus bacteremia and global gene expression by Staphylococcus aureus in human blood. PLoS One 2013; 8:e53391; http://dx.doi.org/10.1371/journal.pone.0053391; PMID: 23308212
  • McCarthy AJ, Lindsay JA. Genetic variation in Staphylococcus aureus surface and immune evasion genes is lineage associated: implications for vaccine design and host-pathogen interactions. BMC Microbiol 2010; 10:173; http://dx.doi.org/10.1186/1471-2180-10-173; PMID: 20550675
  • Daoud AK, Tayyar MA, Fouda IM, Harfeil NA. Effects of diabetes mellitus vs. in vitro hyperglycemia on select immune cell functions. J Immunotoxicol 2009; 6:36 - 41; http://dx.doi.org/10.1080/15476910802604564; PMID: 19519161
  • Yano H, Kinoshita M, Fujino K, Nakashima M, Yamamoto Y, Miyazaki H, Hamada K, Ono S, Iwaya K, Saitoh D, et al. Insulin treatment directly restores neutrophil phagocytosis and bactericidal activity in diabetic mice and thereby improves surgical site Staphylococcus aureus infection. Infect Immun 2012; 80:4409 - 16; http://dx.doi.org/10.1128/IAI.00787-12; PMID: 23027538
  • Mylotte JM, Tayara A. Staphylococcus aureus bacteremia: predictors of 30-day mortality in a large cohort. Clin Infect Dis 2000; 31:1170 - 4; http://dx.doi.org/10.1086/317421; PMID: 11073748
  • Jaber BL. Bacterial infections in hemodialysis patients: pathogenesis and prevention. Kidney Int 2005; 67:2508 - 19; http://dx.doi.org/10.1111/j.1523-1755.2005.00364.x; PMID: 15882306
  • Nibbering PH, Broug-Holub E, Bezemer AC, Jansen R, van de Winkel JG, Geertsma MF. Phagocytosis and intracellular killing of serum-opsonized Staphylococcus aureus by mouse fibroblasts expressing human Fcgamma receptor type IIa (CD32). Front Biosci 1996; 1:a25 - 33; PMID: 9159191
  • Schiff DE, Rae J, Martin TR, Davis BH, Curnutte JT. Increased phagocyte Fc gammaRI expression and improved Fc gamma-receptor-mediated phagocytosis after in vivo recombinant human interferon-gamma treatment of normal human subjects. Blood 1997; 90:3187 - 94; PMID: 9376602
  • Rigby KM, DeLeo FR. Neutrophils in innate host defense against Staphylococcus aureus infections. Semin Immunopathol 2012; 34:237 - 59; http://dx.doi.org/10.1007/s00281-011-0295-3; PMID: 22080185
  • Bruhns P. Properties of mouse and human IgG receptors and their contribution to disease models. Blood 2012; 119:5640 - 9; http://dx.doi.org/10.1182/blood-2012-01-380121; PMID: 22535666
  • Fossati G, Moots RJ, Bucknall RC, Edwards SW. Differential role of neutrophil Fcgamma receptor IIIB (CD16) in phagocytosis, bacterial killing, and responses to immune complexes. Arthritis Rheum 2002; 46:1351 - 61; http://dx.doi.org/10.1002/art.10230; PMID: 12115243
  • Etz H, Minh DB, Henics T, Dryla A, Winkler B, Triska C, Boyd AP, Söllner J, Schmidt W, von Ahsen U, et al. Identification of in vivo expressed vaccine candidate antigens from Staphylococcus aureus.. Proc Natl Acad Sci U S A 2002; 99:6573 - 8; http://dx.doi.org/10.1073/pnas.092569199; PMID: 11997460
  • Köck R, Becker K, Cookson B, van Gemert-Pijnen JE, Harbarth S, Kluytmans J, Mielke M, Peters G, Skov RL, Struelens MJ, et al. Methicillin-resistant Staphylococcus aureus (MRSA): burden of disease and control challenges in Europe. Euro Surveill 2010; 15:19688; PMID: 20961515
  • David MZ, Daum RS. Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic. Clin Microbiol Rev 2010; 23:616 - 87; http://dx.doi.org/10.1128/CMR.00081-09; PMID: 20610826
  • Pancari G, Fan H, Smith S, Joshi A, Haimbach R, Clark D, Li Y, Hua J, McKelvey T, Ou Y, et al. Characterization of the mechanism of protection mediated by CS-D7, a monoclonal antibody to Staphylococcus aureus iron regulated surface determinant B (IsdB). Front Cell Infect Microbiol 2012; 2:36; http://dx.doi.org/10.3389/fcimb.2012.00036; PMID: 22919628
  • Spaan AN, Surewaard BG, Nijland R, van Strijp JA. Neutrophils versus Staphylococcus aureus: a biological tug of war. Annu Rev Microbiol 2013; 67:629 - 50; http://dx.doi.org/10.1146/annurev-micro-092412-155746; PMID: 23834243
  • Fowler VG, Allen KB, Moreira ED, Moustafa M, Isgro F, Boucher HW, Corey GR, Carmeli Y, Betts R, Hartzel JS, et al. Effect of an investigational vaccine for preventing Staphylococcus aureus infections after cardiothoracic surgery: a randomized trial. JAMA 2013; 309:1368 - 78; http://dx.doi.org/10.1001/jama.2013.3010; PMID: 23549582
  • Shinefield H, Black S, Fattom A, Horwith G, Rasgon S, Ordonez J, Yeoh H, Law D, Robbins JB, Schneerson R, et al. Use of a Staphylococcus aureus conjugate vaccine in patients receiving hemodialysis. N Engl J Med 2002; 346:491 - 6; http://dx.doi.org/10.1056/NEJMoa011297; PMID: 11844850
  • DeJonge M, Burchfield D, Bloom B, Duenas M, Walker W, Polak M, Jung E, Millard D, Schelonka R, Eyal F, et al. Clinical trial of safety and efficacy of INH-A21 for the prevention of nosocomial staphylococcal bloodstream infection in premature infants. J Pediatr 2007; 151:260 - 5, e1; http://dx.doi.org/10.1016/j.jpeds.2007.04.060; PMID: 17719934
  • Talbot GH. Considerations in undertaking a clinical development program for hospital-acquired bacterial pneumonia and/or ventilator-associated bacterial pneumonia. Clin Infect Dis 2010; 51:Suppl 1 S144 - 9; http://dx.doi.org/10.1086/653064; PMID: 20597665
  • Spellberg B, Talbot G, Infectious Diseases Society of America (IDSA), American College of Chest Physicians (ACCP), American Thoracic Society (ATS), Society of Critical Care Medicine (SCCM). Recommended design features of future clinical trials of antibacterial agents for hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia. Clin Infect Dis 2010; 51:Suppl 1 S150 - 70; http://dx.doi.org/10.1086/653065; PMID: 20597666
  • Porter CJ, Burden RP, Morgan AG, Daniels I, Fletcher J. Impaired polymorphonuclear neutrophil function in end-stage renal failure and its correction by continuous ambulatory peritoneal dialysis. Nephron 1995; 71:133 - 7; http://dx.doi.org/10.1159/000188700; PMID: 8569942
  • Porter CJ, Burden RP, Morgan AG, Daniels I, Fletcher J. Impaired bacterial killing and hydrogen peroxide production by polymorphonuclear neutrophils in end-stage renal failure. Nephron 1997; 77:479 - 81; http://dx.doi.org/10.1159/000190328; PMID: 9434073
  • Kettleborough CA, Saldanha J, Heath VJ, Morrison CJ, Bendig MM. Humanization of a mouse monoclonal antibody by CDR-grafting: the importance of framework residues on loop conformation. Protein Eng 1991; 4:773 - 83; http://dx.doi.org/10.1093/protein/4.7.773; PMID: 1798701

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