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Trends in capacity utilization for therapeutic monoclonal antibody production

Pages 151-156 | Received 01 Dec 2008, Accepted 08 Jan 2008, Published online: 01 Mar 2009

References

  • Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975; 256:495 - 497
  • Das RC, Morrow KJ. Antibody technologies rise to new challenges. Am Biotechnol Lab 2007; 25:9 - 11
  • Butler M. Animal cell cultures: recent achievements and perspectives in the production of biopharmaceuticals. Appl Microbiol Biotechnol 2005; 68:283 - 291
  • 5th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production 2008; Bioplan Associates, Inc
  • Source: US Federal Reserve Statistical Release, Industrial Production Capacity and Utilization 2008;
  • Source: US Federal Reserve Statistical Release, Industrial Production Capacity and Utilization 2008; November 17 2008 http://www.federalreserve.gov/releases/G17/Current/
  • Ranshoff T. According to industry data, by 2005, the biopharmaceutical contract manufacturing industry had grown to an estimated $1.5 billion. CMOs now hold between 15–29% of the industry-wide capacity for both mammalian cell culture and microbial fermentation. BioPharm International 2007;
  • Morin N, Stevens J. Diverging Measures of Capacity Utilization: An Explanation, Divisions of Research & Statistics and Monetary Affairs, Federal Reserve Board 2004; 2009 Washington DC http://www.federalreserve.gov/pubs/feds/2004/200458/200458pap.pdf

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