Advanced search
Publication Cover
OncoImmunology Volume 2, 2013 - Issue 5
Submit an article Journal homepage
676
Views
11
CrossRef citations to date
0
Altmetric
Author's View

The two faces of regulatory T cells in cancer

Nichole R Blatner Robert H. Lurie Comprehensive Cancer Center; Northwestern University; Chicago, IL USA
,
Fotini Gounari Section of Rheumatology; Department of Medicine; University of Chicago; Chicago, IL USA
&
Khashayarsha Khazaie Robert H. Lurie Comprehensive Cancer Center; Northwestern University; Chicago, IL USACorrespondence[email protected]
Article: e23852 | Received 29 Jan 2013, Accepted 31 Jan 2013, Published online: 15 Apr 2013

References

  • Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce-Pagès C, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006; 313:1960 - 4; http://dx.doi.org/10.1126/science.1129139; PMID: 17008531
  • Khazaie K, Bonertz A, Beckhove P. Current developments with peptide-based human tumor vaccines. Curr Opin Oncol 2009; 21:524 - 30; http://dx.doi.org/10.1097/CCO.0b013e328331a78e; PMID: 19770763
  • Wilke CM, Kryczek I, Wei S, Zhao E, Wu K, Wang G, et al. Th17 cells in cancer: help or hindrance?. Carcinogenesis 2011; 32:643 - 9; http://dx.doi.org/10.1093/carcin/bgr019; PMID: 21304053
  • Khazaie K, Blatner NR, Khan MW, Gounari F, Gounaris E, Dennis K, et al. The significant role of mast cells in cancer. Cancer Metastasis Rev 2011; 30:45 - 60; http://dx.doi.org/10.1007/s10555-011-9286-z; PMID: 21287360
  • Gounaris E, Blatner NR, Dennis K, Magnusson F, Gurish MF, Strom TB, et al. T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory phenotype in polyposis. Cancer Res 2009; 69:5490 - 7; http://dx.doi.org/10.1158/0008-5472.CAN-09-0304; PMID: 19570783
  • Blatner NR, Bonertz A, Beckhove P, Cheon EC, Krantz SB, Strouch M, et al. In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction. Proc Natl Acad Sci U S A 2010; 107:6430 - 5; http://dx.doi.org/10.1073/pnas.0913683107; PMID: 20308560
  • Blatner NR, Mulcahy MF, Dennis KL, Scholtens D, Bentrem DJ, Phillips JD, et al. Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer. Sci Transl Med 2012; 4:ra159; http://dx.doi.org/10.1126/scitranslmed.3004566; PMID: 23241743
  • Tosolini M, Kirilovsky A, Mlecnik B, Fredriksen T, Mauger S, Bindea G, et al. Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. Cancer Res 2011; 71:1263 - 71; http://dx.doi.org/10.1158/0008-5472.CAN-10-2907; PMID: 21303976
  • Bos PD, Rudensky AY. Treg cells in cancer: a case of multiple personality disorder. Sci Transl Med 2012; 4:64fs44; http://dx.doi.org/10.1126/scitranslmed.3005283; PMID: 23241741
  • Erdman SE, Poutahidis T. Cancer inflammation and regulatory T cells. Int J Cancer 2010; 127:768 - 79; PMID: 20518013

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.