504
Views
2
CrossRef citations to date
0
Altmetric
Editorial

p53 further extends its reach

&
Article: e24959 | Received 01 May 2013, Accepted 01 May 2013, Published online: 01 May 2013

References

  • Lane DP. Cancer. p53, guardian of the genome. Nature 1992; 358:15 - 6; http://dx.doi.org/10.1038/358015a0; PMID: 1614522
  • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88:323 - 31; http://dx.doi.org/10.1016/S0092-8674(00)81871-1; PMID: 9039259
  • Wahl GM, Linke SP, Paulson TG, Huang LC. Maintaining genetic stability through TP53 mediated checkpoint control. Cancer Surv 1997; 29:183 - 219; PMID: 9338102
  • Lujambio A, Akkari L, Simon J, Grace D, Tschaharganeh DF, Bolden JE, et al. Non-Cell-Autonomous Tumor Suppression by p53. Cell 2013; 153:449 - 60; http://dx.doi.org/10.1016/j.cell.2013.03.020; PMID: 23562644
  • Coppé JP, Patil CK, Rodier F, Sun Y, Muñoz DP, Goldstein J, et al. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol 2008; 6:2853 - 68; http://dx.doi.org/10.1371/journal.pbio.0060301; PMID: 19053174
  • Chien Y, Scuoppo C, Wang X, Fang X, Balgley B, Bolden JE, et al. Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity. Genes Dev 2011; 25:2125 - 36; http://dx.doi.org/10.1101/gad.17276711; PMID: 21979375
  • Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature 2008; 454:436 - 44; http://dx.doi.org/10.1038/nature07205; PMID: 18650914
  • Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010; 140:883 - 99; http://dx.doi.org/10.1016/j.cell.2010.01.025; PMID: 20303878
  • Cassetta L, Cassol E, Poli G. Macrophage polarization in health and disease. ScientificWorldJournal 2011; 11:2391 - 402; http://dx.doi.org/10.1100/2011/213962; PMID: 22194670
  • Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 2012; 122:787 - 95; http://dx.doi.org/10.1172/JCI59643; PMID: 22378047
  • Sica A, Allavena P, Mantovani A. Cancer related inflammation: the macrophage connection. Cancer Lett 2008; 267:204 - 15; http://dx.doi.org/10.1016/j.canlet.2008.03.028; PMID: 18448242
  • Nakagawa H, Maeda S. Inflammation- and stress-related signaling pathways in hepatocarcinogenesis. World J Gastroenterol 2012; 18:4071 - 81; http://dx.doi.org/10.3748/wjg.v18.i31.4071; PMID: 22919237
  • Shirabe K, Mano Y, Muto J, Matono R, Motomura T, Toshima T, et al. Role of tumor-associated macrophages in the progression of hepatocellular carcinoma. Surg Today 2012; 42:1 - 7; http://dx.doi.org/10.1007/s00595-011-0058-8; PMID: 22116397
  • Yang MH, Chen CL, Chau GY, Chiou SH, Su CW, Chou TY, et al. Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma. Hepatology 2009; 50:1464 - 74; http://dx.doi.org/10.1002/hep.23221; PMID: 19821482
  • Jing Y, Han Z, Liu Y, Sun K, Zhang S, Jiang G, et al. Mesenchymal stem cells in inflammation microenvironment accelerates hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition. PLoS One 2012; 7:e43272; http://dx.doi.org/10.1371/journal.pone.0043272; PMID: 22952657
  • van Zijl F, Mair M, Csiszar A, Schneller D, Zulehner G, Huber H, et al. Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge. Oncogene 2009; 28:4022 - 33; http://dx.doi.org/10.1038/onc.2009.253; PMID: 19718050
  • Brandon-Warner E, Walling TL, Schrum LW, McKillop IH. Chronic ethanol feeding accelerates hepatocellular carcinoma progression in a sex-dependent manner in a mouse model of hepatocarcinogenesis. Alcohol Clin Exp Res 2012; 36:641 - 53; http://dx.doi.org/10.1111/j.1530-0277.2011.01660.x; PMID: 22017344
  • Capece D, Fischietti M, Verzella D, Gaggiano A, Cicciarelli G, Tessitore A, et al. The inflammatory microenvironment in hepatocellular carcinoma: a pivotal role for tumor-associated macrophages. Biomed Res Int 2013; 2013:187204; http://dx.doi.org/10.1155/2013/187204; PMID: 23533994
  • Breuhahn K, Vreden S, Haddad R, Beckebaum S, Stippel D, Flemming P, et al. Molecular profiling of human hepatocellular carcinoma defines mutually exclusive interferon regulation and insulin-like growth factor II overexpression. Cancer Res 2004; 64:6058 - 64; http://dx.doi.org/10.1158/0008-5472.CAN-04-0292; PMID: 15342387
  • Maeda S, Kamata H, Luo JL, Leffert H, Karin M. IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 2005; 121:977 - 90; http://dx.doi.org/10.1016/j.cell.2005.04.014; PMID: 15989949
  • Luedde T, Beraza N, Kotsikoris V, van Loo G, Nenci A, De Vos R, et al. Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 2007; 11:119 - 32; http://dx.doi.org/10.1016/j.ccr.2006.12.016; PMID: 17292824
  • Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, et al. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 2004; 431:461 - 6; http://dx.doi.org/10.1038/nature02924; PMID: 15329734