Wnt/β-catenin signaling in hepatic organogenesis

References

• Cadigan KM, Nusse R. Wnt signaling: a common theme in animal development. Genes & development 1997; 11:3286 - 3305
   PubMed Web of Science ®Google Scholar
• Nusse R. Wnt signaling in disease and in development. Cell research 2005; 15:28 - 32
   PubMed Web of Science ®Google Scholar
• Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004; 20:781 - 810
   PubMed Web of Science ®Google Scholar
• Peifer M, Polakis P. Wnt signaling in oncogenesis and embryogenesis—a look outside the nucleus. Science 2000; 287:1606 - 1609
   PubMed Web of Science ®Google Scholar
• Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR 3rd, Nusse R. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 2003; 423:448 - 452
   PubMed Web of Science ®Google Scholar
• Polakis P. Wnt signaling and cancer. Genes & development 2000; 14:1837 - 1851
   PubMed Web of Science ®Google Scholar
• Koch A, Denkhaus D, Albrecht S, Leuschner I, von Schweinitz D, Pietsch T. Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. Cancer Res 1999; 59:269 - 273
   PubMed Web of Science ®Google Scholar
• Oda H, Imai Y, Nakatsuru Y, Hata J, Ishikawa T. Somatic mutations of the APC gene in sporadic hepatoblastomas. Cancer Res 1996; 56:3320 - 3323
   PubMed Web of Science ®Google Scholar
• Miao J, Kusafuka T, Udatsu Y, Okada A. Sequence variants of the Axin gene in hepatoblastoma. Hepatol Res 2003; 25:174 - 179
   PubMed Web of Science ®Google Scholar
• Satoh S, Daigo Y, Furukawa Y, Kato T, Miwa N, Nishiwaki T, Kawasoe T, Ishiguro H, Fujita M, Tokino T, Sasaki Y, Imaoka S, Murata M, Shimano T, Yamaoka Y, Nakamura Y. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat Gen 2000; 24:245 - 250
   PubMed Web of Science ®Google Scholar
• de La Coste A, Romagnolo B, Billuart P, Renard CA, Buendia MA, Soubrane O, Fabre M, Chelly J, Beldjord C, Kahn A, Perret C. Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc Natl Acad Sci USA 1998; 95:8847 - 8851
   PubMed Web of Science ®Google Scholar
• Wong CM, Fan ST, Ng IO. beta-Catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance. Cancer 2001; 92:136 - 145
   PubMed Web of Science ®Google Scholar
• Merle P, de la Monte S, Kim M, Herrmann M, Tanaka S, Von Dem Bussche A, Kew MC, Trepo C, Wands JR. Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma. Gastroenterology 2004; 127:1110 - 1122
   PubMed Web of Science ®Google Scholar
• Ban KC, Singh H, Krishnan R, Seow HF. GSK-3beta phosphorylation and alteration of beta-catenin in hepatocellular carcinoma. Cancer Lett 2003; 199:201 - 208
   PubMed Web of Science ®Google Scholar
• Behari J, Zeng G, Otruba W, Thompson MD, Muller P, Micsenyi A, Sekhon SS, Leoni L, Monga SP. R-Etodolac decreases beta-catenin levels along with survival and proliferation of hepatoma cells. J Hepatol 2007; 46:849 - 857
   PubMed Web of Science ®Google Scholar
• Zeng G, Apte U, Cieply B, Singh S, Monga SP. siRNA-mediated beta-catenin knockdown in human hepatoma cells results in decreased growth and survival. Neoplasia 2007; 9:951 - 959
   PubMed Web of Science ®Google Scholar
• Thompson MD, Monga SP. WNT/beta-catenin signaling in liver health and disease. Hepatology 2007; 45:1298 - 1305
   PubMed Web of Science ®Google Scholar
• Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006; 127:469 - 480
   PubMed Web of Science ®Google Scholar
• Cadigan KM, Liu YI. Wnt signaling: complexity at the surface. J Cell Sci 2006; 119:395 - 402
   PubMed Web of Science ®Google Scholar
• Lilien J, Balsamo J. The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of beta-catenin. Curr Opin Cell Biol 2005; 17:459 - 465
   PubMed Web of Science ®Google Scholar
• Roura S, Miravet S, Piedra J, Garcia de Herreros A, Dunach M. Regulation of E-cadherin/Catenin association by tyrosine phosphorylation. J Biol Chem 1999; 274:36734 - 36740
   PubMed Web of Science ®Google Scholar
• Theard D, Steiner M, Kalicharan D, Hoekstra D, van Ijzendoorn SC. Cell polarity development and protein trafficking in hepatocytes lacking E-cadherin/beta-catenin-based adherens junctions. Mol Biol Cell 2007; 18:2313 - 2321
   PubMed Web of Science ®Google Scholar
• Tang Y, Kitisin K, Jogunoori W, Li C, Deng CX, Mueller S, Ressom H, Rashid A, He AR, Mendelson JS, Shetty K, Zasloff M, Mishra B, Reddy EP, Johnson L, Mishra L. Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling. Proc Natl Acad Sci USA 2008; In press
   Web of Science ®Google Scholar
• Peinado H, Quintanilla M, Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J Biol Chem 2003; 278:21113 - 21123
   PubMed Web of Science ®Google Scholar
• Katuri V, Tang Y, Li C, Jogunoori W, Deng CX, Rashid A, Sidawy AN, Evans S, Reddy EP, Mishra B, Mishra L. Critical interactions between TGF-beta signaling/ELF, and E-cadherin/beta-catenin mediated tumor suppression. Oncogene 2006; 25:1871 - 1886
   PubMed Web of Science ®Google Scholar
• Zarnegar R. Regulation of HGF and HGFR gene expression. Exs 1995; 74:33 - 49
   PubMedGoogle Scholar
• Monga SP, Mars WM, Pediaditakis P, Bell A, Mule K, Bowen WC, Wang X, Zarnegar R, Michalopoulos GK. Hepatocyte growth factor induces Wnt-independent nuclear translocation of beta-catenin after Met-beta-catenin dissociation in hepatocytes. Cancer Res 2002; 62:2064 - 2071
   PubMed Web of Science ®Google Scholar
• Apte U, Zeng G, Muller P, Tan X, Micsenyi A, Cieply B, Dai C, Liu Y, Kaestner KH, Monga SP. Activation of Wnt/beta-catenin pathway during hepatocyte growth factor-induced hepatomegaly in mice. Hepatology 2006; 44:992 - 1002
   PubMed Web of Science ®Google Scholar
• Ishibe S, Haydu JE, Togawa A, Marlier A, Cantley LG. Cell confluence regulates hepatocyte growth factor-stimulated cell morphogenesis in a beta-catenin-dependent manner. Mol Cell Biol 2006; 26:9232 - 9243
   PubMed Web of Science ®Google Scholar
• Tward AD, Jones KD, Yant S, Cheung ST, Fan ST, Chen X, Kay MA, Wang R, Bishop JM. Distinct pathways of genomic progression to benign and malignant tumors of the liver. Proc Natl Acad Sci USA 2007; 104:14771 - 14776
   PubMed Web of Science ®Google Scholar
• Micsenyi A, Tan X, Sneddon T, Luo JH, Michalopoulos GK, Monga SP. Beta-catenin is temporally regulated during normal liver development. Gastroenterology 2004; 126:1134 - 1146
   PubMed Web of Science ®Google Scholar
• Apte U, Zeng G, Thompson MD, Muller P, Micsenyi A, Cieply B, Kaestner KH, Monga SP. beta-Catenin is critical for early postnatal liver growth. Am J Physiol 2007; 292:1578 - 1585
   PubMed Web of Science ®Google Scholar
• Tan X, Behari J, Cieply B, Michalopoulos GK, Monga SP. Conditional deletion of beta-catenin reveals its role in liver growth and regeneration. Gastroenterology 2006; 131:1561 - 1572
   PubMed Web of Science ®Google Scholar
• Sekine S, Lan BY, Bedolli M, Feng S, Hebrok M. Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice. Hepatology 2006; 43:817 - 825
   PubMed Web of Science ®Google Scholar
• Cadoret A, Ovejero C, Saadi-Kheddouci S, Souil E, Fabre M, Romagnolo B, Kahn A, Perret C. Hepatomegaly in transgenic mice expressing an oncogenic form of beta-catenin. Cancer Res 2001; 61:3245 - 3249
   PubMed Web of Science ®Google Scholar
• Harada N, Miyoshi H, Murai N, Oshima H, Tamai Y, Oshima M, Taketo MM. Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin. Cancer Res 2002; 62:1971 - 1977
   PubMed Web of Science ®Google Scholar
• Tan X, Apte U, Micsenyi A, Kotsagrelos E, Luo JH, Ranganathan S, Monga DK, Bell A, Michalopoulos GK, Monga SP. Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver. Gastroenterology 2005; 129:285 - 302
   PubMed Web of Science ®Google Scholar
• Gonzalez FJ. Role of beta-catenin in the adult liver. Hepatology 2006; 43:650 - 653
   PubMed Web of Science ®Google Scholar
• Michalopoulos GK, DeFrances MC. Liver regeneration. Science 1997; 276:60 - 66
   PubMed Web of Science ®Google Scholar
• Monga SP, Pediaditakis P, Mule K, Stolz DB, Michalopoulos GK. Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration. Hepatology 2001; 33:1098 - 1109
   PubMed Web of Science ®Google Scholar
• Sodhi D, Micsenyi A, Bowen WC, Monga DK, Talavera JC, Monga SP. Morpholino oligonucleotide-triggered beta-catenin knockdown compromises normal liver regeneration. Journal of hepatology 2005; 43:132 - 141
   PubMed Web of Science ®Google Scholar
• Sekine S, Gutierrez PJ, Lan BY, Feng S, Hebrok M. Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy. Hepatology 2007; 45:361 - 368
   PubMed Web of Science ®Google Scholar
• Haber B, Naji L, Cressman D, Taub R. Coexpression of liver-specific and growth-induced genes in perinatal and regenerating liver: attainment and maintenance of the differentiated state during rapid proliferation. Hepatology 1995; 22:906 - 914
   PubMed Web of Science ®Google Scholar
• Zaret KS. Molecular genetics of early liver development. Ann. Rev Physiol 1996; 58:231 - 251
   PubMed Web of Science ®Google Scholar
• Zaret KS. Hepatocyte differentiation: from the endoderm and beyond. Curr Opin Genet Dev 2001; 11:568 - 574
   PubMed Web of Science ®Google Scholar
• Zaret KS. Regulatory phases of early liver development: paradigms of organogenesis. Nat Rev 2002; 3:499 - 512
   Google Scholar
• Spear BT, Jin L, Ramasamy S, Dobierzewska A. Transcriptional control in the mammalian liver: liver development, perinatal repression, and zonal gene regulation. Cell Mol Life Sci 2006; 63:2922 - 2938
   PubMed Web of Science ®Google Scholar
• Lee CS, Friedman JR, Fulmer JT, Kaestner KH. The initiation of liver development is dependent on Foxa transcription factors. Nature 2005; 435:944 - 947
   PubMed Web of Science ®Google Scholar
• Jung J, Zheng M, Goldfarb M, Zaret KS. Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science 1999; 284:1998 - 2003
   PubMed Web of Science ®Google Scholar
• Matsumoto K, Yoshitomi H, Rossant J, Zaret KS. Liver organogenesis promoted by endothelial cells prior to vascular function. Science 2001; 294:559 - 563
   PubMed Web of Science ®Google Scholar
• Rossi JM, Dunn NR, Hogan BL, Zaret KS. Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes Dev 2001; 15:1998 - 2009
   PubMed Web of Science ®Google Scholar
• Duncan SA. Transcriptional regulation of liver development. Dev Dyn 2000; 219:131 - 142
   PubMed Web of Science ®Google Scholar
• Schmidt C, Bladt F, Goedecke S, Brinkmann V, Zschiesche W, Sharpe M, Gherardi E, Birchmeier C. Scatter factor/hepatocyte growth factor is essential for liver development. Nature 1995; 373:699 - 702
   PubMed Web of Science ®Google Scholar
• Zhang W, Yatskievych TA, Baker RK, Antin PB. Regulation of Hex gene expression and initial stages of avian hepatogenesis by Bmp and Fgf signaling. Dev Biol 2004; 268:312 - 326
   PubMed Web of Science ®Google Scholar
• Martinez Barbera JP, Clements M, Thomas P, Rodriguez T, Meloy D, Kioussis D, Beddington RS. The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation. Development 2000; 127:2433 - 2445
   PubMed Web of Science ®Google Scholar
• Bort R, Signore M, Tremblay K, Martinez Barbera JP, Zaret KS. Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development. Dev Biol 2006; 290:44 - 56
   PubMed Web of Science ®Google Scholar
• Hunter MP, Wilson CM, Jiang X, Cong R, Vasavada H, Kaestner KH, Bogue CW. The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesis. Dev Biol 2007; 308:355 - 367
   PubMed Web of Science ®Google Scholar
• Hentsch B, Lyons I, Li R, Hartley L, Lints TJ, Adams JM, Harvey RP. Hlx homeo box gene is essential for an inductive tissue interaction that drives expansion of embryonic liver and gut. Genes Dev 1996; 10:70 - 79
   PubMed Web of Science ®Google Scholar
• Sosa-Pineda B, Wigle JT, Oliver G. Hepatocyte migration during liver development requires Prox1. Nat Gen 2000; 25:254 - 255
   PubMed Web of Science ®Google Scholar
• Zaret K. Early liver differentiation: genetic potentiation and multilevel growth control. Current opinion in genetics & development 1998; 8:526 - 531
   PubMed Web of Science ®Google Scholar
• Zaret KS. Liver specification and early morphogenesis. Mech Dev 2000; 92:83 - 88
   PubMed Web of Science ®Google Scholar
• Odom DT, Zizlsperger N, Gordon DB, Bell GW, Rinaldi NJ, Murray HL, Volkert TL, Schreiber J, Rolfe PA, Gifford DK, Fraenkel E, Bell GI, Young RA. Control of pancreas and liver gene expression by HNF transcription factors. Science 2004; 303:1378 - 1381
   PubMed Web of Science ®Google Scholar
• Darlington GJ, Wang N, Hanson RW. C/EBP alpha: a critical regulator of genes governing integrative metabolic processes. Curr Opin Genet Dev 1995; 5:565 - 570
   PubMed Web of Science ®Google Scholar
• Parviz F, Matullo C, Garrison WD, Savatski L, Adamson JW, Ning G, Kaestner KH, Rossi JM, Zaret KS, Duncan SA. Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Gen 2003; 34:292 - 296
   PubMed Web of Science ®Google Scholar
• Zhao R, Watt AJ, Li J, Luebke-Wheeler J, Morrisey EE, Duncan SA. GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol Cell Biol 2005; 25:2622 - 2631
   PubMed Web of Science ®Google Scholar
• Clotman F, Lannoy VJ, Reber M, Cereghini S, Cassiman D, Jacquemin P, Roskams T, Rousseau GG, Lemaigre FP. The onecut transcription factor HNF6 is required for normal development of the biliary tract. Development 2002; 129:1819 - 1828
   PubMed Web of Science ®Google Scholar
• Coffinier C, Gresh L, Fiette L, Tronche F, Schutz G, Babinet C, Pontoglio M, Yaniv M, Barra J. Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1beta. Development 2002; 129:1829 - 1838
   PubMed Web of Science ®Google Scholar
• Lorent K, Yeo SY, Oda T, Chandrasekharappa S, Chitnis A, Matthews RP, Pack M. Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy. Development 2004; 131:5753 - 5766
   PubMed Web of Science ®Google Scholar
• Burke ZD, Thowfeequ S, Tosh D. Liver specification: a new role for Wnts in liver development. Curr Biol 2006; 16:688 - 690
   Web of Science ®Google Scholar
• Shackel N. Zebrafish and the understanding of liver development: the emerging role of the Wnt pathway in liver biology. Hepatology 2007; 45:540 - 541
   PubMedGoogle Scholar
• Thorpe CJ, Schlesinger A, Carter JC, Bowerman B. Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm. Cell 1997; 90:695 - 705
   PubMed Web of Science ®Google Scholar
• Heasman J, Crawford A, Goldstone K, Garner Hamrick P, Gumbiner B, McCrea P, Kintner C, Noro CY, Wylie C. Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos. Cell 1994; 79:791 - 803
   PubMed Web of Science ®Google Scholar
• Haegel H, Larue L, Ohsugi M, Fedorov L, Herrenknecht K, Kemler R. Lack of beta-catenin affects mouse development at gastrulation. Development 1995; 121:3529 - 3537
   PubMed Web of Science ®Google Scholar
• Popperl H, Schmidt C, Wilson V, Hume CR, Dodd J, Krumlauf R, Beddington RS. Misexpression of Cwnt8C in the mouse induces an ectopic embryonic axis and causes a truncation of the anterior neuroectoderm. Development 1997; 124:2997 - 3005
   PubMed Web of Science ®Google Scholar
• Stark K, Vainio S, Vassileva G, McMahon AP. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 1994; 372:679 - 683
   PubMed Web of Science ®Google Scholar
• Zorn AM, Butler K, Gurdon JB. Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGFbeta signalling pathways. Developmental biology 1999; 209:282 - 297
   PubMed Web of Science ®Google Scholar
• Lemaigre F, Zaret KS. Liver development update: new embryo models, cell lineage control, and morphogenesis. Curr Opin Genet Dev 2004; 14:582 - 590
   PubMed Web of Science ®Google Scholar
• McLin VA, Rankin SA, Zorn AM. Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development 2007; 134:2207 - 2217
   PubMed Web of Science ®Google Scholar
• Finley KR, Tennessen J, Shawlot W. The mouse secreted frizzled-related protein 5 gene is expressed in the anterior visceral endoderm and foregut endoderm during early post-implantation development. Gene Expr Patterns 2003; 3:681 - 684
   PubMed Web of Science ®Google Scholar
• Pilcher KE, Krieg PA. Expression of the Wnt inhibitor, sFRP5, in the gut endoderm of Xenopus. Gene Expr Patterns 2002; 2:369 - 372
   PubMedGoogle Scholar
• Yoshida Y, Kim S, Chiba K, Kawai S, Tachikawa H, Takahashi N. Calcineurin inhibitors block dorsal-side signaling that affect late-stage development of the heart, kidney, liver, gut and somitic tissue during Xenopus embryogenesis. Dev Growth Differ 2004; 46:139 - 152
   PubMed Web of Science ®Google Scholar
• Ober EA, Verkade H, Field HA, Stainier DY. Mesodermal Wnt2b signalling positively regulates liver specification. Nature 2006; 442:688 - 691
   PubMed Web of Science ®Google Scholar
• Monga SP, Monga HK, Tan X, Mule K, Pediaditakis P, Michalopoulos GK. Beta-catenin antisense studies in embryonic liver cultures: role in proliferation, apoptosis, and lineage specification. Gastroenterology 2003; 124:202 - 216
   PubMed Web of Science ®Google Scholar
• Suksaweang S, Lin CM, Jiang TX, Hughes MW, Widelitz RB, Chuong CM. Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation. Dev Biol 2004; 266:109 - 122
   PubMed Web of Science ®Google Scholar
• Hoeflich KP, Luo J, Rubie EA, Tsao MS, Jin O, Woodgett JR. Requirement for glycogen synthase kinase-3beta in cell survival and NFkappaB activation. Nature 2000; 406:86 - 90
   PubMed Web of Science ®Google Scholar
• Decaens T, Godard C, de Reynies A, Rickman DS, Tronche F, Couty JP, Perret C, Colnot S. Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. Hepatology 2007;
   Web of Science ®Google Scholar
• Wang QM, Yang KM, Zhou HY, Li X, Yang HJ, Li YS. The role of beta-catenin in rat embryonic development and tumorigenesis. Sichuan Da Xue Xue Bao Yi Xue Ban 2006; 37:872 - 875
   PubMedGoogle Scholar
• Monga SP, Hout MS, Baun MJ, Micsenyi A, Muller P, Tummalapalli L, Ranade AR, Luo JH, Strom SC, Gerlach JC. Mouse fetal liver cells in artificial capillary beds in three-dimensional four-compartment bioreactors. Am J Pathol 2005; 167:1279 - 1292
   PubMed Web of Science ®Google Scholar
• Fausto N, Campbell JS. The role of hepatocytes and oval cells in liver regeneration and repopulation. Mec Dev 2003; 120:117 - 130
   PubMed Web of Science ®Google Scholar
• Masson NM, Currie IS, Terrace JD, Garden OJ, Parks RW, Ross JA. Hepatic progenitor cells in human fetal liver express the oval cell marker Thy-1. Am J Physiol 2006; 291:45 - 54
   PubMed Web of Science ®Google Scholar
• Hu M, Kurobe M, Jeong YJ, Fuerer C, Ghole S, Nusse R, Sylvester KG. Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells. Gastroenterology 2007; 133:1579 - 1591
   PubMed Web of Science ®Google Scholar
• Apte U, Thompson MD, Cui S, Liu B, Cieply B, Monga SP. Wnt/beta-catenin signaling mediates oval cell response in rodents. Hepatology 2007;
   PubMed Web of Science ®Google Scholar
• Hussain SZ, Sneddon T, Tan X, Micsenyi A, Michalopoulos GK, Monga SP. Wnt impacts growth and differentiation in ex vivo liver development. Exp Cell Res 2004; 292:157 - 169
   PubMed Web of Science ®Google Scholar
• Monga SP, Micsenyi A, Germinaro M, Apte U, Bell A. beta-Catenin regulation during matrigel-induced rat hepatocyte differentiation. Cell Tissue Res 2006; 323:71 - 79
   PubMed Web of Science ®Google Scholar
• Tan X, Yuan Y, Zeng G U A, Thompson MD, Cieply B, Stolz DB, Michalopoulos GK, Kaestner KH, Monga SP. Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development. Hepatology 2008; 47:1 - 13
   PubMed Web of Science ®Google Scholar
• Burke ZD, Tosh D. The Wnt/beta-catenin pathway: master regulator of liver zonation?. Bioessays 2006; 28:1072 - 1077
   PubMed Web of Science ®Google Scholar
• Eisenberg LM, Eisenberg CA. Evaluating the role of Wnt signal transduction in promoting the development of the heart. The Scientific World Journal 2007; 7:161 - 176
   Web of Science ®Google Scholar
• Tzahor E. Wnt/beta-catenin signaling and cardiogenesis: timing does matter. Dev Cell 2007; 13:10 - 13
   PubMed Web of Science ®Google Scholar
• Lickert H, Kispert A, Kutsch S, Kemler R. Expression patterns of Wnt genes in mouse gut development. Mec Dev 2001; 105:181 - 184
   PubMed Web of Science ®Google Scholar
• Ang SJ, Stump RJ, Lovicu FJ, McAvoy JW. Spatial and temporal expression of Wnt and Dickkopf genes during murine lens development. Gene Expr Patterns 2004; 4:289 - 295
   Google Scholar
• Naito AT, Shiojima I, Akazawa H, Hidaka K, Morisaki T, Kikuchi A, Komuro I. Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis. Proc Natl Acad Sci USA 2006; 103:19812 - 19817
   PubMed Web of Science ®Google Scholar
• Kim BM, Mao J, Taketo MM, Shivdasani RA. Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Gastroenterology 2007; 133:529 - 538
   PubMed Web of Science ®Google Scholar
• Berg T, Rountree CB, Lee L, Estrada J, Sala FG, Choe A, Veltmaat JM, De Langhe S, Lee R, Tsukamoto H, Crooks GM, Bellusci S, Wang KS. Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via beta-catenin activation. Hepatology 2007; 46:1187 - 1197
   PubMed Web of Science ®Google Scholar
• Sekhon SS, Tan X, Micsenyi A, Bowen WC, Monga SP. Fibroblast growth factor enriches the embryonic liver cultures for hepatic progenitors. Am J Pathol 2004; 164:2229 - 2240
   PubMed Web of Science ®Google Scholar
• Kawakami Y, Capdevila J, Buscher D, Itoh T, Rodriguez Esteban C, Izpisua Belmonte JC. WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo. Cell 2001; 104:891 - 900
   PubMed Web of Science ®Google Scholar
• Shu W, Guttentag S, Wang Z, Andl T, Ballard P, Lu MM, Piccolo S, Birchmeier W, Whitsett JA, Millar SE, Morrisey EE. Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol 2005; 283:226 - 239
   PubMed Web of Science ®Google Scholar