Renal organogenesis

References

• Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, et al. Prevalence of chronic kidney disease in the United States. JAMA 2007; 298:2038 - 2047; PMID: 17986697; http://dx.doi.org/10.1001/jama.298.17.2038
   PubMed Web of Science ®Google Scholar
• National Kidney & Urologic Diseases Information Clearinghouse (NKUDIC). http://kidney.niddk.nih.gov/kudiseases/pubs/kustats/
   Google Scholar
• Hopkins C, Li J, Rae F, Little MH. Stem cell options for kidney disease. J Pathol 2009; 217:265 - 281; PMID: 19058290; http://dx.doi.org/10.1002/path.2477
   PubMed Web of Science ®Google Scholar
• Harding SD, Armit C, Armstrong J, Brennan J, Cheng Y, Haggarty B, et al. The GUDMAP Database—An Online Resource for Genitourinary Research. Development 2011; 138:2845 - 2853; PMID: 21652655; http://dx.doi.org/10.1242/dev.063594
   PubMed Web of Science ®Google Scholar
• McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, et al. GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol 2008; 19:667 - 671; PMID: 18287559; http://dx.doi.org/10.1681/ASN.2007101078
   PubMed Web of Science ®Google Scholar
• Hendry C, Rumballe BA, Moritz K, Little MH. Defining and redefining the nephron progenitor population. Pediatr Nephrol 2011; 26:1395 - 1406; PMID: 21229268; http://dx.doi.org/10.1007/s00467-010-1750-4
   PubMed Web of Science ®Google Scholar
• Kopan R, Cheng HT, Surendran K. Molecular insightss into segmentation along the proximal-distal axis of the nephron. J Am Soc Nephrol 2007; 18:2014 - 2020; PMID: 17568016; http://dx.doi.org/10.1681/ASN.2007040453
   PubMed Web of Science ®Google Scholar
• Carroll TJ, Park JS, Hayashi S, Majumdar A, McMahon AP. Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell 2005; 9:283 - 292; PMID: 16054034; http://dx.doi.org/10.1016/j.devcel.2005.05.016
   PubMed Web of Science ®Google Scholar
• Park JS, Valerius MT, McMahon AP. Wnt/betacatenin signaling regulates nephron induction during mouse kidney development. Development 2007; 134:2533 - 2539; PMID: 17537789; http://dx.doi.org/10.1242/dev.006155
   PubMed Web of Science ®Google Scholar
• Stark K, Vainio S, Vassileva G, McMahon AP. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 1994; 372:679 - 683; PMID: 7990960; http://dx.doi.org/10.1038/372679a0
   PubMed Web of Science ®Google Scholar
• Perantoni AO, Timofeeva O, Naillat F, Richman C, Pajni-Underwood S, Wilson C, et al. Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development. Development 2005; 132:3859 - 3871; PMID: 16049111; http://dx.doi.org/10.1242/dev.01945
   PubMed Web of Science ®Google Scholar
• Burn SF, Webb A, Berry RL, Davies JA, Ferrer-Vaquer A, Hadjantonakis AK, et al. Calcium/NFAT signalling promotes early nephrogenesis. Dev Biol 2011; 352:288 - 298; PMID: 21295565; http://dx.doi.org/10.1016/j.ydbio.2011.01.033
   PubMed Web of Science ®Google Scholar
• Tanigawa S, Wang H, Yang Y, Sharma N, Tarasova N, Ajima R, et al. Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism. Dev Biol 2011; 352:58 - 69; PMID: 21256838; http://dx.doi.org/10.1016/j.ydbio.2011.01.012
   PubMed Web of Science ®Google Scholar
• Saxen L. Barlow PW, Green PB, White CC. Organogenesis of the Kidney. Developmental and Cell Biology Series 19 1987; Cambridge, UK Cambridge University Press 19
   Google Scholar
• Mugford JW, Sipila P, McMahon JA, McMahon AP. Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney. Dev Biol 2008; 324:88 - 98; PMID: 18835385; http://dx.doi.org/10.1016/j.ydbio.2008.09.010
   PubMed Web of Science ®Google Scholar
• Boyle S, Misfeldt A, Chandler KJ, Deal KK, Southard-Smith EM, Mortlock DP, et al. Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia. Dev Biol 2008; 313:234 - 245; PMID: 18061157; http://dx.doi.org/10.1016/j.ydbio.2007.10.014
   PubMed Web of Science ®Google Scholar
• Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, Oliver G, et al. Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell 2008; 3:169 - 181; PMID: 18682239; http://dx.doi.org/10.1016/j.stem.2008.05.020
   PubMed Web of Science ®Google Scholar
• Self M, Lagutin OV, Bowling B, Hendrix J, Cai Y, Dressler GR, et al. Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney. EMBO J 2006; 25:5214 - 5228; PMID: 17036046; http://dx.doi.org/10.1038/sj.emboj.7601381
   PubMed Web of Science ®Google Scholar
• Brunskill EW, Aronow BJ, Georgas K, Rumballe B, Valerius MT, Aronow J, et al. Atlas of gene expression in the developing kidney at microanatomic resolution. Dev Cell 2008; 15:781 - 791; PMID: 19000842; http://dx.doi.org/10.1016/j.devcel.2008.09.007
   PubMed Web of Science ®Google Scholar
• Thiagarajan RD, Georgas K, Rumballe B, Lesieur E, Chiu H, Taylor D, et al. Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS ONE 2011; 6:17286; PMID: 21386911; http://dx.doi.org/10.1371/journal.pone.0017286
   PubMed Web of Science ®Google Scholar
• Georgas K, Rumballe BA, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, et al. Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol 2009; 332:273 - 286; PMID: 19501082; http://dx.doi.org/10.1016/j.ydbio.2009.05.578
   PubMed Web of Science ®Google Scholar
• Rumballe B, Georgas KM, Combes AN, Ju AL, Gilbert T, Little MH. Nephron formation adopts a novel spatial topology at cessation of nephrogenesis. Dev Biol 2011; In Press
   PubMed Web of Science ®Google Scholar
• Witzgall R, Brown D, Schwarz C, Bonventre JV. Localization of proliferating cell nuclear antigen, vimentin, c-Fos and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J Clin Invest 1994; 93:2175 - 2188; PMID: 7910173; http://dx.doi.org/10.1172/JCI117214
   PubMed Web of Science ®Google Scholar
• Vogetseder A, Picard N, Gaspert A, Walch M, Kaissling B, Le Hir M. Proliferation capacity of the renal proximal tubule involves the bulk of differentiated epithelial cells. Am J Physiol Cell Physiol 2008; 294:22 - 28; PMID: 17913845; http://dx.doi.org/10.1152/ajpcell.00227.2007
   PubMed Web of Science ®Google Scholar
• Cochrane AL, Kett MM, Samuel CS, Campanale NV, Anderson WP, Hume DA, et al. Renal structural and functional repair in a mouse model of reversal of ureteral obstruction. J Am Soc Nephrol 2005; 16:3623 - 3630; PMID: 16221872; http://dx.doi.org/10.1681/ASN.2004090771
   PubMed Web of Science ®Google Scholar
• Lin F, Moran A, Igarashi P. Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney. J Clin Invest 2005; 115:1756 - 1764; PMID: 16007252; http://dx.doi.org/10.1172/JCI23015
   PubMed Web of Science ®Google Scholar
• Duffield JS, Park KM, Hsiao LL, Kelley VR, Scadden DT, Ichimura T, et al. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest 2005; 115:1743 - 1755; PMID: 16007251; http://dx.doi.org/10.1172/JCI22593
   PubMed Web of Science ®Google Scholar
• Challen GA, Bertoncello I, Deane JA, Ricardo SD, Little MH. Kidney side population reveals multi-lineage potential and renal functional capacity but also cellular heterogeneity. J Am Soc Nephrol 2006; 17:1896 - 1912; PMID: 16707564; http://dx.doi.org/10.1681/ASN.2005111228
   PubMed Web of Science ®Google Scholar
• Villanueva S, Ewertz E, Carrión F, Tapia A, Vergara C, Céspedes C, et al. Mesenchymal stem cell injection ameliorates chronic renal failure in a rat model. Clin Sci (Lond) 2011; 121:489 - 499; PMID: 21675962; http://dx.doi.org/10.1042/CS20110108
   PubMed Web of Science ®Google Scholar
• Tögel F, Hu Z, Weiss K, Isaac J, Lange C, Westenfelder C. Administered mesenchymal stem cells protect against ischemic acute renal failure through differ-entiation-independent mechanisms. Am J Physiol Renal Physiol 2005; 289:31 - 42; PMID: 15713913; http://dx.doi.org/10.1152/ajprenal.00007.2005
   PubMed Web of Science ®Google Scholar
• Lusis M, Ineson J, Li J, Little MH. Isolation and culture of metanephric mesenchyme-derived nephrospheres reinforces evidence that embryonic renal progenitors are multipotent and exhaust during cessation of nephron formation. Stem Cell Res (Amst) 2010; 5:23 - 39; http://dx.doi.org/10.1016/j.scr.2010.03.003
   PubMed Web of Science ®Google Scholar
• Humphreys BD, Valerius MT, Kobayashi A, Mugford JW, Soeung S, Duffield JS, et al. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell 2008; 2:284 - 291; PMID: 18371453; http://dx.doi.org/10.1016/j.stem.2008.01.014
   PubMed Web of Science ®Google Scholar
• Langworthy M, Zhou B, de Caestecker M, Moeckel G, Baldwin HS. NFATc1 identifies a population of proximal tubule cell progenitors. J Am Soc Nephrol 2009; 20:311 - 321; PMID: 19118153; http://dx.doi.org/10.1681/ASN.2008010094
   PubMed Web of Science ®Google Scholar
• Ronconi E, Sagrinati C, Angelotti ML, Lazzeri E, Mazzinghi B, Ballerini L, et al. Regeneration of glomerular podocytes by human renal progenitors. J Am Soc Nephrol 2009; 20:322 - 332; PMID: 19092120; http://dx.doi.org/10.1681/ASN.2008070709
   PubMed Web of Science ®Google Scholar
• Appel D, Kershaw DB, Smeets B, Yuan G, Fuss A, Frye B, et al. Recruitment of podocytes from glomerular parietal epithelial cells. J Am Soc Nephrol 2009; 20:333 - 343; PMID: 19092119; http://dx.doi.org/10.1681/ASN.2008070795
   PubMed Web of Science ®Google Scholar
• Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284:143 - 147; PMID: 10102814; http://dx.doi.org/10.1126/science.284.5411.143
   PubMed Web of Science ®Google Scholar
• da Silva Meirelles L, Chagastelles PC, Nardi NB. Mesenchymal stem cells reside in virtually all postnatal organs and tissues. J Cell Sci 2006; 119:2204 - 2213; PMID: 16684817; http://dx.doi.org/10.1242/jcs.02932
   PubMed Web of Science ®Google Scholar
• Plotkin MD, Goligorsky MS. Mesenchymal cells from adult kidney support angiogenesis and differentiate into multiple interstitial cell types including erythropoietin producing fibroblasts. Am J Physiol Renal Physiol 2006; 291:902 - 912; PMID: 16622175; http://dx.doi.org/10.1152/ajprenal.00396.2005
   PubMed Web of Science ®Google Scholar
• Gupta S, Verfaillie C, Chmielewski D, Kren S, Eidman K, Connaire J, et al. Isolation and characterization of kidney-derived stem cells. J Am Soc Nephrol 2006; 17:3028 - 3040; PMID: 16988061; http://dx.doi.org/10.1681/ASN.2006030275
   PubMed Web of Science ®Google Scholar
• Dekel B, Zangi L, Shezen E, Reich-Zeliger S, Eventov-Friedman S, Katchman H, et al. Isolation and characterization of nontubular sca-1+lin− multipotent stem/progenitor cells from adult mouse kidney. J Am Soc Nephrol 2006; 17:3300 - 3314; PMID: 17093069; http://dx.doi.org/10.1681/ASN.2005020195
   PubMed Web of Science ®Google Scholar
• Crisan M, Yap S, Casteilla L, Chen CW, Corselli M, Park TS, et al. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 2008; 3:301 - 313; PMID: 18786417; http://dx.doi.org/10.1016/j.stem.2008.07.003
   PubMed Web of Science ®Google Scholar
• Friedenstein AJ, Deriglasova UF, Kulagina NN, Panasuk AF, Rudakowa SF, Luria EA, et al. Precursors for fibroblasts in different populations of hematopoietic cells as detected by the in vitro colony assay method. Exp Hematol 1974; 2:83 - 92; PMID: 4455512
   PubMed Web of Science ®Google Scholar
• Pelekanos RA, Li J, Gongora M, Chandrakanthan V, Scown J, Suhaimi N, et al. Comprehensive transcriptome and immunophenotype analysis of renal and cardiac MSC-like populations supports strong congruence with bone marrow MSC despite maintenance of distinct identities. Stem Cell Res (Amst) 2011; In press http://dx.doi.org/10.1016/j.scr.2011.08.003
   Google Scholar
• Wilkinson L, Gilbert T, Kinna G, Ruta LA, Pennisi D, Kett M, et al. Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development. J Am Soc Nephrol 2007; 18:1697 - 1708; PMID: 17460146; http://dx.doi.org/10.1681/ASN.2006091012
   PubMed Web of Science ®Google Scholar
• Pennisi DJ, Wilkinson L, Kolle G, Sohaskey ML, Gillinder K, Piper MJ, et al. Crim1KST264/KST264 mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systems. Dev Dyn 2007; 236:502 - 511; PMID: 17106887; http://dx.doi.org/10.1002/dvdy.21015
   PubMed Web of Science ®Google Scholar
• Oliver JA, Maarouf O, Cheema FH, Martens TP, Al-Awqati Q, et al. The renal papilla is a niche for adult kidney stem cells. J Clin Invest 2004; 114:795 - 804; PMID: 15372103
   PubMed Web of Science ®Google Scholar
• Xu X, D'Hoker J, Stangé G, Bonné S, De Leu N, Xiao X, et al. Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 2008; 132:197 - 207; PMID: 18243096; http://dx.doi.org/10.1016/j.cell.2007.12.015
   PubMed Web of Science ®Google Scholar
• Cantz T, Manns MP, Ott M. Stem cells in liver regeneration and therapy. Cell Tissue Res 2008; 331:271 - 282; PMID: 17901986; http://dx.doi.org/10.1007/s00441-0070483-6
   PubMed Web of Science ®Google Scholar
• Oliver JA, Klinakis A, Cheema FH, Friedlander J, Sampogna RV, Martens TP, et al. Proliferation and migration of label-retaining cells of the kidney papilla. J Am Soc Nephrol 2009; 20:2315 - 2327; PMID: 19762493; http://dx.doi.org/10.1681/ASN.2008111203
   PubMed Web of Science ®Google Scholar
• Haylock DN, Nilsson SK. Osteopontin: a bridge between bone and blood. Br J Haematol 2006; 134:467 - 474; PMID: 16848793; http://dx.doi.org/10.1111/j.1365-2141.2006.06218.x
   PubMed Web of Science ®Google Scholar
• Waddington CH. Organisers & genes 1994; Cambridge Cambridge University Press
   Google Scholar
• Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126:663 - 676; PMID: 16904174; http://dx.doi.org/10.1016/j.cell.2006.07.024
   PubMed Web of Science ®Google Scholar
• Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131:861 - 872; PMID: 18035408; http://dx.doi.org/10.1016/j.cell.2007.11.019
   PubMed Web of Science ®Google Scholar
• Zhou Q, Melton DA. Pathways to new beta cells. Cold Spring Harb Symp Quant Biol 2008; 73:175 - 181; PMID: 19478324; http://dx.doi.org/10.1101/sqb.2008.72.002
   PubMedGoogle Scholar
• Chen S, Borowiak M, Fox JL, Maehr R, Osafune K, Davidow L, et al. A small molecule that directs differentiation of human ESCs into the pancreatic lineage. Nat Chem Biol 2009; 5:258 - 265; PMID: 19287398; http://dx.doi.org/10.1038/nchembio.154
   PubMed Web of Science ®Google Scholar
• Alikhan MA, Jones CV, Williams TM, Beckhouse AG, Fletcher AL, Kett MM, et al. Colony-Stimulating Factor-1 Promotes Kidney Growth and Repair via Alteration of Macrophage Responses. Am J Pathol 2011; 179:1243 - 1256; PMID: 21762674; http://dx.doi.org/10.1016/j.ajpath.2011.05.037
   PubMed Web of Science ®Google Scholar
• Rae F, Woods K, Sasmono T, Campanale N, Taylor D, Ovchinnikov D, et al. Characterisation and trophic functions of murine embryonic macro-phages based upon the use of a CSF-1R-EGFP transgene reporter. Dev Biol 2007; 308:232 - 246; PMID: 17597598; http://dx.doi.org/10.1016/j.ydbio.2007.05.027
   PubMed Web of Science ®Google Scholar
• Humphreys BD, Lin SL, Kobayashi A, Hudson TE, Nowlin BT, Bonventre JV, et al. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol 2010; 176:85 - 97; PMID: 20008127; http://dx.doi.org/10.2353/ajpath.2010.090517
   PubMed Web of Science ®Google Scholar
• Yallowitz AR, Hrycaj SM, Short KM, Smyth IM, Wellik DM. Hox10 genes function in kidney development in the differentiation and integration of the cortical stroma. PLoS ONE 2011; 6:23410; PMID: 21858105; http://dx.doi.org/10.1371/journal.pone.0023410
   PubMed Web of Science ®Google Scholar
• Rumballe B, Georgas K, Little MH. High-throughput paraffin section in situ hybridization and dual immunohistochemistry on mouse tissues. CSH Protoc 2008;
   PubMedGoogle Scholar