Toxic Effects of Intracerebral PrP Antibody Administration During the Course of BSE Infection in Mice

References

• Aguzzi A, Weissmann C. Prion diseases. Haemophilia 1998; 4:619 - 627
   PubMed Web of Science ®Google Scholar
• Lasmézas CI, Weiss S. Cary JW, Linz JE, Bhatnagar D. Molecular biology of prion diseases. Microbial foodborne diseases 2000; Lancaster, USA Technomic Publishing Company, Inc. 495 - 537
   Google Scholar
• Cohen FE, Prusiner SB. Pathologic conformations of prion proteins. Annu Rev Biochem 1998; 67:793 - 819
   PubMed Web of Science ®Google Scholar
• Prusiner SB. Novel proteinaceous infectious particles cause scrapie. Science 1982; 216:136 - 144
   PubMed Web of Science ®Google Scholar
• Prusiner SB. Prions. Proc Natl Acad Sci USA 1998; 95:13363 - 13383
   PubMed Web of Science ®Google Scholar
• Weissmann C, Aguzzi A. Approaches to therapy of prion diseases. Annu Rev Med 2005; 56:321 - 344
   PubMed Web of Science ®Google Scholar
• Trevitt CR, Collinge J. A systematic review of prion therapeutics in experimental models. Brain 2006; 129:2241 - 2265
   PubMed Web of Science ®Google Scholar
• Vana K, Zuber C, Nikles D, Weiss S. Novel aspects of prions, their receptor molecules, and innovative approaches for TSE therapy. Cellular and Molecular Neurobiology 2007; 27:107 - 128
   PubMed Web of Science ®Google Scholar
• Horiuchi M, Caughey B. Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state. EMBO J 1999; 18:3193 - 3203
   PubMed Web of Science ®Google Scholar
• Donofrio G, Heppner FL, Polymenidou M, Musahl C, Aguzzi A. Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies. J Virol 2005; 79:8330 - 8338
   PubMed Web of Science ®Google Scholar
• Enari M, Flechsig E, Weissmann C. Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc Natl Acad Sci USA 2001; 98:9295 - 9299
   PubMed Web of Science ®Google Scholar
• Gilch S, Wopfner F, Renner-Muller I, Kremmer E, Bauer C, Wolf E, Brem G, Groschup MH, Schatzl HM. Polyclonal anti-PrP auto-antibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells. J Biol Chem 2003; 278:18524 - 18531
   PubMed Web of Science ®Google Scholar
• Miyamoto K, Nakamura N, Aosasa M, Nishida N, Yokoyama T, Horiuchi H, Furusawa S, Matsuda H. Inhibition of prion propagation in scrapie-infected mouse neuroblastoma cell lines using mouse monoclonal antibodies against prion protein. Biochem Biophys Res Commun 2005; 335:197 - 204
   PubMed Web of Science ®Google Scholar
• Peretz D, Williamson RA, Kaneko K, Vergara J, Leclerc E, Schmitt-Ulms G, Mehlhorn IR, Legname G, Wormald MR, Rudd PM, Dwek RA, Burton DR, Prusiner SB. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature 2001; 412:739 - 743
   PubMed Web of Science ®Google Scholar
• Feraudet C, Morel N, Simon S, Volland H, Frobert Y, Creminon C, Vilette D, Lehmann S, Grassi J. Screening of 145 anti-PrP monoclonal antibodies for their capacity to inhibit PrPSc replication in infected cells. J Biol Chem 2005; 280:11247 - 11258
   PubMed Web of Science ®Google Scholar
• Beringue V, Vilette D, Mallinson G, Archer F, Kaisar M, Tayebi M, Jackson GS, Clarke AR, Laude H, Collinge J, Hawke S. PrPSc binding antibodies are potent inhibitors of prion replication in cell lines. J Biol Chem 2004; 279:39671 - 39676
   PubMed Web of Science ®Google Scholar
• Perrier V, Solassol J, Crozet C, Frobert Y, Mourton-Gilles C, Grassi J, Lehmann S. Anti-PrP antibodies block PrPSc replication in prion-infected cell cultures by accelerating PrPC degradation. J Neurochem 2004; 89:454 - 463
   PubMed Web of Science ®Google Scholar
• Heppner FL, Musahl C, Arrighi I, Klein MA, Rulicke T, Oesch B, Zinkernagel RM, Kalinke U, Aguzzi A. Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science 2001; 294:178 - 182
   PubMed Web of Science ®Google Scholar
• Bade S, Baier M, Boetel T, Frey A. Intranasal immunization of Balb/c mice against prion protein attenuates orally acquired transmissible spongiform encephalopathy. Vaccine 2006; 24:1242 - 1253
   PubMed Web of Science ®Google Scholar
• Ishibashi D, Yamanaka H, Yamaguchi N, Yoshikawa D, Nakamura R, Okimura N, Yamaguchi Y, Shigematsu K, Katamine S, Sakaguchi S. Immunization with recombinant bovine but not mouse prion protein delays the onset of disease in mice inoculated with a mouse-adapted prion. Vaccine 2007; 25:985 - 992
   PubMed Web of Science ®Google Scholar
• Kimberlin RH, Walker CA. Pathogenesis of mouse scrapie: Dynamics of agent replication in spleen, spinal cord and brain after infection by different routes. J Comp Pathol 1979; 89:551 - 562
   PubMed Web of Science ®Google Scholar
• Magri G, Clerici M, Dall'Ara P, Biasin M, Caramelli M, Casalone C, Giannino ML, Longhi R, Piacentini L, Della Bella S, Gazzuola P, Martino PA, Della Bella S, Pollera C, Puricelli M, Servida F, Crescio I, Boasso A, Ponti W, Poli G. Decrease in pathology and progression of scrapie after immunisation with synthetic prion protein peptides in hamsters. Vaccine 2005; 23:2862 - 2868
   PubMed Web of Science ®Google Scholar
• Polymenidou M, Heppner FL, Pellicioli EC, Urich E, Miele G, Braun N, Wopfner F, Schatzl HM, Becher B, Aguzzi A. Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection. Proc Natl Acad Sci USA 2004; 101:14670 - 14676
   PubMed Web of Science ®Google Scholar
• Schwarz A, Kratke O, Burwinkel M, Riemer C, Schultz J, Henklein P, Bamme T, Baier M. Immunisation with a synthetic prion protein-derived peptide prolongs survival times of mice orally exposed to the scrapie agent. Neurosci Lett 2003; 350:187 - 189
   PubMed Web of Science ®Google Scholar
• Sigurdsson EM, Brown DR, Daniels M, Kascsak RJ, Kascsak R, Carp R, Meeker HC, Frangione B, Wisniewski T. Immunization delays the onset of prion disease in mice. Am J Pathol 2002; 161:13 - 17
   PubMed Web of Science ®Google Scholar
• Gregoire S, Bergot AS, Feraudet C, Carnaud C, Aucouturier P, Rosset MB. The murine B cell repertoire is severely selected against endogenous cellular prion protein. J Immunol 2005; 175:6443 - 6449
   PubMed Web of Science ®Google Scholar
• White AR, Enever P, Tayebi M, Mushens R, Linehan J, Brandner S, Anstee D, Collinge J, Hawke S. Monoclonal antibodies inhibit prion replication and delay the development of prion disease. Nature 2003; 422:80 - 83
   PubMed Web of Science ®Google Scholar
• Solforosi L, Criado JR, McGavern DB, Wirz S, Sanchez-Alavez M, Sugama S, DeGiorgio LA, Volpe BT, Wiseman E, Abalos G, Masliah E, Gilden D, Oldstone MB, Conti B, Williamson RA. Cross-linking cellular prion protein triggers neuronal apoptosis in vivo. Science 2004; 303:1514 - 1516
   PubMed Web of Science ®Google Scholar
• Fischer M, Rulicke T, Raeber A, Sailer A, Moser M, Oesch B, Brandner S, Aguzzi A, Weissmann C. Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J 1996; 15:1255 - 1264
   PubMed Web of Science ®Google Scholar
• Lasmézas CI, Deslys JP, Demaimay R, Adjou KT, Hauw JJ, Dormont D. Strain specific and common pathogenic events in murine models of scrapie and bovine spongiform encephalopathy. J Gen Virol 1996; 77:1601 - 1609
   PubMed Web of Science ®Google Scholar
• Zou WQ, Zheng J, Gray DM, Gambetti P, Chen SG. Antibody to DNA detects scrapie but not normal prion protein. Proc Natl Acad Sci USA 2004; 101:1380 - 1385
   PubMed Web of Science ®Google Scholar
• Williamson RA, Peretz D, Pinilla C, Ball H, Bastidas RB, Rozenshteyn R, Houghten RA, Prusiner SB, Burton DR. Mapping the prion protein using recombinant antibodies. J Virol 1998; 72:9413 - 9418
   PubMed Web of Science ®Google Scholar
• Parry A, Baker I, Stacey R, Wimalaratna S. Long term survival in a patient with variant Creutzfeldt-Jakob disease treated with intraventricular pentosan polysulphate. J Neurol Neurosurg Psychiatr 2007; 78:733 - 734
   PubMed Web of Science ®Google Scholar
• Todd NV, Morrow J, Doh-ura K, Dealler S, O'Hare S, Farling P, Duddy M, Rainov NG. Cerebroventricular infusion of pentosan polysulphate in human variant Creutzfeldt-Jakob disease. J Infect 2005; 50:394 - 396
   PubMed Web of Science ®Google Scholar
• Whittle IR, Knight RS, Will RG. Unsuccessful intraventricular pentosan polysulphate treatment of variant Creutzfeldt-Jakob disease. Acta Neurochir (Wien) 2006; 148:677 - 679
   PubMed Web of Science ®Google Scholar
• Zuber C, Knackmuss S, Rey C, Reusch U, Rottgen P, Frohlich T, Arnold GJ, Pace C, Mitteregger G, Kretzschmar HA, Little M, Weiss S. Single chain Fv antibodies directed against the 37kDa/67kDa laminin receptor as therapeutic tools in prion diseases. Mol Immunol 2008; 45:144 - 151
   PubMed Web of Science ®Google Scholar
• Jansen K, Schafer O, Birkmann E, Post K, Serban H, Prusiner SB, Riesner D. Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form. Biol Chem 2001; 382:683 - 691
   PubMed Web of Science ®Google Scholar
• Zhang Y, Pardridge WM. Mediated efflux of IgG molecules from brain to blood across the blood-brain barrier. J Neuroimmunol 2001; 114:168 - 172
   PubMed Web of Science ®Google Scholar
• Moore RC, Mastrangelo P, Bouzamondo E, Heinrich C, Legname G, Prusiner SB, Hood L, Westaway D, DeArmond SJ, Tremblay P. Doppel-induced cerebellar degeneration in transgenic mice. Proc Natl Acad Sci USA 2001; 98:15288 - 15293
   PubMed Web of Science ®Google Scholar
• Shmerling D, Hegyi I, Fischer M, Blattler T, Brandner S, Gotz J, Rulicke T, Flechsig E, Cozzio A, von Mering C, Hangartner C, Aguzzi A, Weissmann C. Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell 1998; 93:203 - 214
   PubMed Web of Science ®Google Scholar
• Orgogozo JM, Gilman S, Dartigues JF, Laurent B, Puel M, Kirby LC, Jouanny P, Dubois B, Eisner L, Flitman S, Michel BF, Boada M, Frank A, Hock C. Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology 2003; 61:46 - 54
   PubMed Web of Science ®Google Scholar
• Lemere CA, Maier M, Jiang L, Peng Y, Seabrook TJ. Amyloid-beta immunotherapy for the prevention and treatment of Alzheimer disease: Lessons from mice, monkeys, and humans. Rejuvenation Res 2006; 9:77 - 84
   PubMed Web of Science ®Google Scholar