Aggregated proteins in schizophrenia and other chronic mental diseases

References

• American Psychiatric Association APA. Diagnostic and Statistical Manual IV (DSM IV). Washington, D.C., 1994.
   Google Scholar
• an der Heiden W, Häfner H. The epidemiology of onset and course of schizophrenia. Eur Arch Psychiatry Clin Neurosci 2000; 250:292 - 303; http://dx.doi.org/10.1007/s004060070004; PMID: 11153964
   PubMed Web of Science ®Google Scholar
• Kirkpatrick B, Fenton WS, Carpenter WT Jr., Marder SR. The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull 2006; 32:214 - 9; http://dx.doi.org/10.1093/schbul/sbj053; PMID: 16481659
   PubMed Web of Science ®Google Scholar
• Gur RE, Calkins ME, Gur RC, Horan WP, Nuechterlein KH, Seidman LJ, et al. The Consortium on the Genetics of Schizophrenia: neurocognitive endophenotypes. Schizophr Bull 2007; 33:49 - 68; http://dx.doi.org/10.1093/schbul/sbl055; PMID: 17101692
   PubMed Web of Science ®Google Scholar
• Kraepelin E. Zur Diagnose und Prognose der Dementia praecox. Allg Z Psychiatr 1899; 56:246 - 63
   Google Scholar
• Bleuler E. Dementia praecox oder Gruppe der Schizophrenien. Leipzig: F. Deuticke, 1911.
   Google Scholar
• Carpenter WT Jr.. Conceptualizing schizophrenia through attenuated symptoms in the population. Am J Psychiatry 2010; 167:1013 - 6; http://dx.doi.org/10.1176/appi.ajp.2010.10060854; PMID: 20826849
   PubMed Web of Science ®Google Scholar
• Kirkpatrick B, Buchanan RW, Ross DE, Carpenter WT Jr.. A separate disease within the syndrome of schizophrenia. Arch Gen Psychiatry 2001; 58:165 - 71; http://dx.doi.org/10.1001/archpsyc.58.2.165; PMID: 11177118
   PubMed Web of Science ®Google Scholar
• Chua SE, McKenna PJ. A Sceptical View of the Neuropathology of Schizophrenia. In: Harrison PJ, Roberts G.W., ed. The Neuropathology of Schizophrenia. Oxford: Oxford University Press, 2000:291-337.
   Google Scholar
• Delay J, Deniker P, Harl J-M. Traitement des états d’excitation et d’agitation par une méthode médicamenteuse dérivée de l’hibernothérapie. Ann Med Psychol (Paris) 1952; 110:267 - 73; PMID: 13008201
   PubMedGoogle Scholar
• Carlsson A, Lindqvist M. Effect of chlorpromazine or haloperidol on the formation of 3-methoxytyramine and norepinephrine in mouse brain. Acta Pharmacol Toxicol (Copenh) 1963; 20:140 - 4; http://dx.doi.org/10.1111/j.1600-0773.1963.tb01730.x; PMID: 14060771
   PubMedGoogle Scholar
• Davis KL, Kahn RS, Ko G, Davidson M. Dopamine in schizophrenia: a review and reconceptualization. Am J Psychiatry 1991; 148:1474 - 86; PMID: 1681750
   PubMed Web of Science ®Google Scholar
• Howes OD, Kapur S. The dopamine hypothesis of schizophrenia: version III--the final common pathway. Schizophr Bull 2009; 35:549 - 62; http://dx.doi.org/10.1093/schbul/sbp006; PMID: 19325164
   PubMed Web of Science ®Google Scholar
• Weinberger DR. Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 1987; 44:660 - 9; http://dx.doi.org/10.1001/archpsyc.1987.01800190080012; PMID: 3606332
   PubMed Web of Science ®Google Scholar
• Jaaro-Peled H, Hayashi-Takagi A, Seshadri S, Kamiya A, Brandon NJ, Sawa A. Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1. Trends Neurosci 2009; 32:485 - 95; http://dx.doi.org/10.1016/j.tins.2009.05.007; PMID: 19712980
   PubMed Web of Science ®Google Scholar
• Kety SS. The significance of genetic factors in the etiology of schizophrenia: results from the national study of adoptees in Denmark. J Psychiatr Res 1987; 21:423 - 9; http://dx.doi.org/10.1016/0022-3956(87)90089-6; PMID: 3440955
   PubMed Web of Science ®Google Scholar
• Gottesman II, Shields J. A critical review of recent adoption, twin, and family studies of schizophrenia: behavioral genetics perspectives. Schizophr Bull 1976; 2:360 - 401; PMID: 1034336
   PubMed Web of Science ®Google Scholar
• Millar JK, Wilson-Annan JC, Anderson S, Christie S, Taylor MS, Semple CA, et al. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet 2000; 9:1415 - 23; http://dx.doi.org/10.1093/hmg/9.9.1415; PMID: 10814723
   PubMed Web of Science ®Google Scholar
• Stefansson H, Sigurdsson E, Steinthorsdottir V, Bjornsdottir S, Sigmundsson T, Ghosh S, et al. Neuregulin 1 and susceptibility to schizophrenia. Am J Hum Genet 2002; 71:877 - 92; http://dx.doi.org/10.1086/342734; PMID: 12145742
   PubMed Web of Science ®Google Scholar
• Schwab SG, Knapp M, Mondabon S, Hallmayer J, Borrmann-Hassenbach M, Albus M, et al. Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families. Am J Hum Genet 2003; 72:185 - 90; http://dx.doi.org/10.1086/345463; PMID: 12474144
   PubMed Web of Science ®Google Scholar
• Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry 2005; 10:40 - 68; http://dx.doi.org/10.1038/sj.mp.4001558; PMID: 15263907
   PubMed Web of Science ®Google Scholar
• Owen MJ, Craddock N, Jablensky A. The genetic deconstruction of psychosis. Schizophr Bull 2007; 33:905 - 11; http://dx.doi.org/10.1093/schbul/sbm053; PMID: 17551090
   PubMed Web of Science ®Google Scholar
• Craddock N, Owen MJ. Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages. World Psychiatry 2007; 6:84 - 91; PMID: 18235858
   PubMed Web of Science ®Google Scholar
• Kellendonk C, Simpson EH, Kandel ER. Modeling cognitive endophenotypes of schizophrenia in mice. Trends Neurosci 2009; 32:347 - 58; http://dx.doi.org/10.1016/j.tins.2009.02.003; PMID: 19409625
   PubMed Web of Science ®Google Scholar
• Arguello PA, Gogos JA. Modeling madness in mice: one piece at a time. Neuron 2006; 52:179 - 96; http://dx.doi.org/10.1016/j.neuron.2006.09.023; PMID: 17015235
   PubMed Web of Science ®Google Scholar
• Powers ET, Morimoto RI, Dillin A, Kelly JW, Balch WE. Biological and chemical approaches to diseases of proteostasis deficiency. Annu Rev Biochem 2009; 78:959 - 91; http://dx.doi.org/10.1146/annurev.biochem.052308.114844; PMID: 19298183
   PubMed Web of Science ®Google Scholar
• Prusiner SB. Shattuck lecture--neurodegenerative diseases and prions. N Engl J Med 2001; 344:1516 - 26; http://dx.doi.org/10.1056/NEJM200105173442006; PMID: 11357156
   PubMed Web of Science ®Google Scholar
• Taylor JP, Hardy J, Fischbeck KH. Toxic proteins in neurodegenerative disease. Science 2002; 296:1991 - 5; http://dx.doi.org/10.1126/science.1067122; PMID: 12065827
   PubMed Web of Science ®Google Scholar
• Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci USA 1985; 82:4245 - 9; http://dx.doi.org/10.1073/pnas.82.12.4245; PMID: 3159021
   PubMed Web of Science ®Google Scholar
• Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer’s disease. Nature 1991; 349:704 - 6; http://dx.doi.org/10.1038/349704a0; PMID: 1671712
   PubMed Web of Science ®Google Scholar
• Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M. alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with lewy bodies. Proc Natl Acad Sci USA 1998; 95:6469 - 73; http://dx.doi.org/10.1073/pnas.95.11.6469; PMID: 9600990
   PubMed Web of Science ®Google Scholar
• Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, et al. Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease. Science 1997; 276:2045 - 7; http://dx.doi.org/10.1126/science.276.5321.2045; PMID: 9197268
   PubMed Web of Science ®Google Scholar
• Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, et al. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol 2009; 11:909 - 13; http://dx.doi.org/10.1038/ncb1901; PMID: 19503072
   PubMed Web of Science ®Google Scholar
• Desplats P, Lee HJ, Bae EJ, Patrick C, Rockenstein E, Crews L, et al. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc Natl Acad Sci USA 2009; 106:13010 - 5; http://dx.doi.org/10.1073/pnas.0903691106; PMID: 19651612
   PubMed Web of Science ®Google Scholar
• Ren PH, Lauckner JE, Kachirskaia I, Heuser JE, Melki R, Kopito RR. Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates. Nat Cell Biol 2009; 11:219 - 25; http://dx.doi.org/10.1038/ncb1830; PMID: 19151706
   PubMed Web of Science ®Google Scholar
• Münch C, O’Brien J, Bertolotti A. Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells. Proc Natl Acad Sci USA 2011; 108:3548 - 53; http://dx.doi.org/10.1073/pnas.1017275108; PMID: 21321227
   PubMed Web of Science ®Google Scholar
• Grad LI, Guest WC, Yanai A, Pokrishevsky E, O’Neill MA, Gibbs E, et al. Intermolecular transmission of superoxide dismutase 1 misfolding in living cells. Proc Natl Acad Sci USA 2011; 108:16398 - 403; http://dx.doi.org/10.1073/pnas.1102645108; PMID: 21930926
   PubMed Web of Science ®Google Scholar
• Li JY, Englund E, Holton JL, Soulet D, Hagell P, Lees AJ, et al. Lewy bodies in grafted neurons in subjects with Parkinson’s disease suggest host-to-graft disease propagation. Nat Med 2008; 14:501 - 3; http://dx.doi.org/10.1038/nm1746; PMID: 18391963
   PubMed Web of Science ®Google Scholar
• Lee SJ, Desplats P, Sigurdson C, Tsigelny I, Masliah E. Cell-to-cell transmission of non-prion protein aggregates. Nat Rev Neurol 2010; 6:702 - 6; http://dx.doi.org/10.1038/nrneurol.2010.145; PMID: 21045796
   PubMed Web of Science ®Google Scholar
• St Clair D, Blackwood D, Muir W, Carothers A, Walker M, Spowart G, et al. Association within a family of a balanced autosomal translocation with major mental illness. Lancet 1990; 336:13 - 6; http://dx.doi.org/10.1016/0140-6736(90)91520-K; PMID: 1973210
   PubMed Web of Science ®Google Scholar
• Blackwood DH, Fordyce A, Walker MT, St Clair DM, Porteous DJ, Muir WJ. Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. Am J Hum Genet 2001; 69:428 - 33; http://dx.doi.org/10.1086/321969; PMID: 11443544
   PubMed Web of Science ®Google Scholar
• Chubb JE, Bradshaw NJ, Soares DC, Porteous DJ, Millar JK. The DISC locus in psychiatric illness. Mol Psychiatry 2008; 13:36 - 64; http://dx.doi.org/10.1038/sj.mp.4002106; PMID: 17912248
   PubMed Web of Science ®Google Scholar
• Kamiya A, Kubo K, Tomoda T, Takaki M, Youn R, Ozeki Y, et al. A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol 2005; 7:1167 - 78; http://dx.doi.org/10.1038/ncb1328; PMID: 16299498
   PubMed Web of Science ®Google Scholar
• Pletnikov MV, Ayhan Y, Xu Y, Nikolskaia O, Ovanesov M, Huang H, et al. Enlargement of the lateral ventricles in mutant DISC1 transgenic mice. Mol Psychiatry 2008; 13:115; http://dx.doi.org/10.1038/sj.mp.4002144; PMID: 18202691
   PubMedGoogle Scholar
• Hikida T, Jaaro-Peled H, Seshadri S, Oishi K, Hookway C, Kong S, et al. Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proc Natl Acad Sci USA 2007; 104:14501 - 6; http://dx.doi.org/10.1073/pnas.0704774104; PMID: 17675407
   PubMed Web of Science ®Google Scholar
• Shen S, Lang B, Nakamoto C, Zhang F, Pu J, Kuan SL, et al. Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1. J Neurosci 2008; 28:10893 - 904; http://dx.doi.org/10.1523/JNEUROSCI.3299-08.2008; PMID: 18945897
   PubMed Web of Science ®Google Scholar
• Ekelund J, Hovatta I, Parker A, Paunio T, Varilo T, Martin R, et al. Chromosome 1 loci in Finnish schizophrenia families. Hum Mol Genet 2001; 10:1611 - 7; http://dx.doi.org/10.1093/hmg/10.15.1611; PMID: 11468279
   PubMed Web of Science ®Google Scholar
• Hamshere ML, Bennett P, Williams N, Segurado R, Cardno A, Norton N, et al. Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Arch Gen Psychiatry 2005; 62:1081 - 8; http://dx.doi.org/10.1001/archpsyc.62.10.1081; PMID: 16203953
   PubMed Web of Science ®Google Scholar
• Hwu HG, Liu CM, Fann CS, Ou-Yang WC, Lee SF. Linkage of schizophrenia with chromosome 1q loci in Taiwanese families. Mol Psychiatry 2003; 8:445 - 52; http://dx.doi.org/10.1038/sj.mp.4001235; PMID: 12740602
   PubMed Web of Science ®Google Scholar
• Thomson PA, Wray NR, Millar JK, Evans KL, Hellard SL, Condie A, et al. Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population. Mol Psychiatry 2005; 10:6 57 - 68; http://dx.doi.org/10.1038/sj.mp.4001669; PMID: 15838535
   PubMed Web of Science ®Google Scholar
• Hennah W, Tuulio-Henriksson A, Paunio T, Ekelund J, Varilo T, Partonen T, et al. A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia. Mol Psychiatry 2005; 10:1097 - 103; http://dx.doi.org/10.1038/sj.mp.4001731; PMID: 16103888
   PubMed Web of Science ®Google Scholar
• Cannon TD, Hennah W, van Erp TG, Thompson PM, Lonnqvist J, Huttunen M, et al. Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory. Arch Gen Psychiatry 2005; 62:1205 - 13; http://dx.doi.org/10.1001/archpsyc.62.11.1205; PMID: 16275808
   PubMed Web of Science ®Google Scholar
• Qu M, Tang F, Yue W, Ruan Y, Lu T, Liu Z, et al. Positive association of the Disrupted-in-Schizophrenia-1 gene (DISC1) with schizophrenia in the Chinese Han population. Am J Med Genet B Neuropsychiatr Genet 2007; 144B:266 - 70; http://dx.doi.org/10.1002/ajmg.b.30322; PMID: 17286247
   PubMed Web of Science ®Google Scholar
• Palo OM, Antila M, Silander K, Hennah W, Kilpinen H, Soronen P, et al. Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments. Hum Mol Genet 2007; 16:2517 - 28; http://dx.doi.org/10.1093/hmg/ddm207; PMID: 17673452
   PubMed Web of Science ®Google Scholar
• Thomson PA, Harris SE, Starr JM, Whalley LJ, Porteous DJ, Deary IJ. Association between genotype at an exonic SNP in DISC1 and normal cognitive aging. Neurosci Lett 2005; 389:41 - 5; http://dx.doi.org/10.1016/j.neulet.2005.07.004; PMID: 16054297
   PubMed Web of Science ®Google Scholar
• Hashimoto R, Numakawa T, Ohnishi T, Kumamaru E, Yagasaki Y, Ishimoto T, et al. Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling. Hum Mol Genet 2006; 15:3024 - 33; http://dx.doi.org/10.1093/hmg/ddl244; PMID: 16959794
   PubMed Web of Science ®Google Scholar
• Kilpinen H, Ylisaukko-Oja T, Hennah W, Palo OM, Varilo T, Vanhala R, et al. Association of DISC1 with autism and Asperger syndrome. Mol Psychiatry 2008; 13:187 - 96; http://dx.doi.org/10.1038/sj.mp.4002031; PMID: 17579608
   PubMed Web of Science ®Google Scholar
• Bradshaw NJ, Porteous DJ. DISC1-binding proteins in neural development, signalling and schizophrenia. Neuropharmacology 2010; PMID: 21195721
   PubMed Web of Science ®Google Scholar
• Korth C. DISCopathies: brain disorders related to DISC1 dysfunction. Rev Neurosci 2009; 20:321 - 30; http://dx.doi.org/10.1515/REVNEURO.2009.20.5-6.321; PMID: 20397618
   PubMed Web of Science ®Google Scholar
• Pletnikov MV, Ayhan Y, Nikolskaia O, Xu Y, Ovanesov MV, Huang H, et al. Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia. Mol Psychiatry 2008; 13:173 - 86; http://dx.doi.org/10.1038/sj.mp.4002079; PMID: 17848917
   PubMed Web of Science ®Google Scholar
• Clapcote SJ, Lipina TV, Millar JK, Mackie S, Christie S, Ogawa F, et al. Behavioral phenotypes of Disc1 missense mutations in mice. Neuron 2007; 54:387 - 402; http://dx.doi.org/10.1016/j.neuron.2007.04.015; PMID: 17481393
   PubMed Web of Science ®Google Scholar
• Kuroda K, Yamada S, Tanaka M, Iizuka M, Yano H, Mori D, et al. Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse. Hum Mol Genet 2011; 20:4666 - 83; http://dx.doi.org/10.1093/hmg/ddr400; PMID: 21903668
   PubMed Web of Science ®Google Scholar
• Camargo LM, Collura V, Rain JC, Mizuguchi K, Hermjakob H, Kerrien S, et al. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. Mol Psychiatry 2007; 12:74 - 86; http://dx.doi.org/10.1038/sj.mp.4001880; PMID: 17043677
   PubMed Web of Science ®Google Scholar
• Soares CC, Carlyle BC, Bradshaw NJ, Porteous D. DISC1: Structure, Function, and Therapeutic Postential for Major Mental Illness. ACS Chem Neurosci 2011:dx.doi.org/10.1021/cn200062k.
   Google Scholar
• Kirkpatrick B, Xu L, Cascella N, Ozeki Y, Sawa A, Roberts RC. DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex. J Comp Neurol 2006; 497:436 - 50; http://dx.doi.org/10.1002/cne.21007; PMID: 16736468
   PubMed Web of Science ®Google Scholar
• Brandon NJ, Sawa A. Linking neurodevelopmental and synaptic theories of mental illness through DISC1. Nat Rev Neurosci 2011; 12:707 - 22; http://dx.doi.org/10.1038/nrn3120; PMID: 22095064
   PubMed Web of Science ®Google Scholar
• Torrey EF, Webster M, Knable M, Johnston N, Yolken RH. The stanley foundation brain collection and neuropathology consortium. Schizophr Res 2000; 44:151 - 5; http://dx.doi.org/10.1016/S0920-9964(99)00192-9; PMID: 10913747
   PubMed Web of Science ®Google Scholar
• Leliveld SR, Bader V, Hendriks P, Prikulis I, Sajnani G, Requena JR, et al. Insolubility of disrupted-in-schizophrenia 1 disrupts oligomer-dependent interactions with nuclear distribution element 1 and is associated with sporadic mental disease. J Neurosci 2008; 28:3839 - 45; http://dx.doi.org/10.1523/JNEUROSCI.5389-07.2008; PMID: 18400883
   PubMed Web of Science ®Google Scholar
• Ottis P, Bader V, Trossbach S, Kretzschmar H, Michel M, Leliveld SR, et al. Convergence of two independent mental disease genes on the protein level: recruitment of dysbindin to cell-invasive disrupted-in-schizophrenia 1 aggresomes. Biol Psychiatry 2011; 70:604 - 10; http://dx.doi.org/10.1016/j.biopsych.2011.03.027; PMID: 21531389
   PubMed Web of Science ®Google Scholar
• Mangiarini L, Sathasivam K, Seller M, Cozens B, Harper A, Hetherington C, et al. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 1996; 87:493 - 506; http://dx.doi.org/10.1016/S0092-8674(00)81369-0; PMID: 8898202
   PubMed Web of Science ®Google Scholar
• Blackwood DH, Muir WJ. Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia. Neurotox Res 2004; 6:35 - 41; http://dx.doi.org/10.1007/BF03033294; PMID: 15184103
   PubMed Web of Science ®Google Scholar
• Masison DC, Wickner RB. Prion-inducing domain of yeast Ure2p and protease resistance of Ure2p in prion-containing cells. Science 1995; 270:93 - 5; http://dx.doi.org/10.1126/science.270.5233.93; PMID: 7569955
   PubMed Web of Science ®Google Scholar
• Greenwald J, Riek R. Biology of amyloid: structure, function, and regulation. Structure 2010; 18:1244 - 60; http://dx.doi.org/10.1016/j.str.2010.08.009; PMID: 20947013
   PubMed Web of Science ®Google Scholar
• Braak H, Del Tredici K. Alzheimer’s pathogenesis: is there neuron-to-neuron propagation?. Acta Neuropathol 2011; 121:589 - 95; http://dx.doi.org/10.1007/s00401-011-0825-z; PMID: 21516512
   PubMed Web of Science ®Google Scholar
• Soto C. Prion hypothesis: the end of the controversy?. Trends Biochem Sci 2011; 36:151 - 8; http://dx.doi.org/10.1016/j.tibs.2010.11.001; PMID: 21130657
   PubMed Web of Science ®Google Scholar
• Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, et al. Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science 2006; 313:1781 - 4; http://dx.doi.org/10.1126/science.1131864; PMID: 16990547
   PubMed Web of Science ®Google Scholar
• Morales R, Duran-Aniotz C, Castilla J, Estrada LD, Soto C. De novo induction of amyloid-β deposition in vivo. Mol Psychiatry 2011; http://dx.doi.org/10.1038/mp.2011.120; PMID: 21968933
   PubMed Web of Science ®Google Scholar
• Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991; 82:239 - 59; http://dx.doi.org/10.1007/BF00308809; PMID: 1759558
   PubMed Web of Science ®Google Scholar
• Braak H, Del Tredici K, Rüb U, de Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol Aging 2003; 24:197 - 211; http://dx.doi.org/10.1016/S0197-4580(02)00065-9; PMID: 12498954
   PubMed Web of Science ®Google Scholar
• Brandon NJ, Millar JK, Korth C, Sive H, Singh KK, Sawa A. Understanding the role of DISC1 in psychiatric disease and during normal development. J Neurosci 2009; 29:12768 - 75; http://dx.doi.org/10.1523/JNEUROSCI.3355-09.2009; PMID: 19828788
   PubMed Web of Science ®Google Scholar
• Young-Pearse TL, Suth S, Luth ES, Sawa A, Selkoe DJ. Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development. J Neurosci 2010; 30:10431 - 40; http://dx.doi.org/10.1523/JNEUROSCI.1445-10.2010; PMID: 20685985
   PubMed Web of Science ®Google Scholar
• Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Doud MK, et al. Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell 2009; 136:1017 - 31; http://dx.doi.org/10.1016/j.cell.2008.12.044; PMID: 19303846
   PubMed Web of Science ®Google Scholar
• Millar JK, Pickard BS, Mackie S, James R, Christie S, Buchanan SR, et al. DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science 2005; 310:1187 - 91; http://dx.doi.org/10.1126/science.1112915; PMID: 16293762
   PubMed Web of Science ®Google Scholar
• Kamiya A, Tan PL, Kubo K, Engelhard C, Ishizuka K, Kubo A, et al. Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses. Arch Gen Psychiatry 2008; 65:996 - 1006; http://dx.doi.org/10.1001/archpsyc.65.9.996; PMID: 18762586
   PubMed Web of Science ®Google Scholar
• Ishizuka K, Kamiya A, Oh EC, Kanki H, Seshadri S, Robinson JF, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature 2011; 473:92 - 6; http://dx.doi.org/10.1038/nature09859; PMID: 21471969
   PubMed Web of Science ®Google Scholar
• Olzscha H, Schermann SM, Woerner AC, Pinkert S, Hecht MH, Tartaglia GG, et al. Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions. Cell 2011; 144:67 - 78; http://dx.doi.org/10.1016/j.cell.2010.11.050; PMID: 21215370
   PubMed Web of Science ®Google Scholar
• Di Giorgio A, Blasi G, Sambataro F, Rampino A, Papazacharias A, Gambi F, et al. Association of the SerCys DISC1 polymorphism with human hippocampal formation gray matter and function during memory encoding. Eur J Neurosci 2008; 28:2129 - 36; http://dx.doi.org/10.1111/j.1460-9568.2008.06482.x; PMID: 19046394
   PubMed Web of Science ®Google Scholar
• Kamiya A, Tomoda T, Chang J, Takaki M, Zhan C, Morita M, et al. DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1. Hum Mol Genet 2006; 15:3313 - 23; http://dx.doi.org/10.1093/hmg/ddl407; PMID: 17035248
   PubMed Web of Science ®Google Scholar
• Leliveld SR, Hendriks P, Michel M, Sajnani G, Bader V, Trossbach S, et al. Oligomer assembly of the C-terminal DISC1 domain (640-854) is controlled by self-association motifs and disease-associated polymorphism S704C. Biochemistry 2009; 48:7746 - 55; http://dx.doi.org/10.1021/bi900901e; PMID: 19583211
   PubMed Web of Science ®Google Scholar
• Narayanan S, Arthanari H, Wolfe MS, Wagner G. Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly. J Biol Chem 2011; 286:44266 - 76; http://dx.doi.org/10.1074/jbc.M111.271593; PMID: 21998303
   PubMed Web of Science ®Google Scholar
• Brandon NJ, Handford EJ, Schurov I, Rain JC, Pelling M, Duran-Jimeniz B, et al. Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders. Mol Cell Neurosci 2004; 25:42 - 55; http://dx.doi.org/10.1016/j.mcn.2003.09.009; PMID: 14962739
   PubMed Web of Science ®Google Scholar
• Shen Y, Li N, Wu S, Zhou Y, Shan Y, Zhang Q, et al. Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells. Dev Cell 2008; 14:342 - 53; http://dx.doi.org/10.1016/j.devcel.2008.01.001; PMID: 18331715
   PubMed Web of Science ®Google Scholar
• Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano SI, Hayashi-Takagi A, et al. Disrupted-in-Schizphrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proc Natl Acad Sci USA 2010; 107:5622 - 7; http://dx.doi.org/10.1073/pnas.0909284107; PMID: 20212127
   PubMed Web of Science ®Google Scholar