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Mini Review

Elucidating the role of cofactors in mammalian prion propagation

Pages 100-105 | Received 01 Oct 2013, Accepted 12 Dec 2013, Published online: 01 Jan 2013

References

  • Prusiner SB. Prions. Proc Natl Acad Sci U S A 1998; 95:13363 - 83; http://dx.doi.org/10.1073/pnas.95.23.13363; PMID: 9811807
  • Raeber AJ, Borchelt DR, Scott M, Prusiner SB. Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems. J Virol 1992; 66:6155 - 63; PMID: 1356161
  • Bessen RA, Kocisko DA, Raymond GJ, Nandan S, Lansbury PT, Caughey B. Non-genetic propagation of strain-specific properties of scrapie prion protein. Nature 1995; 375:698 - 700; http://dx.doi.org/10.1038/375698a0; PMID: 7791905
  • Kocisko DA, Come JH, Priola SA, Chesebro B, Raymond GJ, Lansbury PT, Caughey B. Cell-free formation of protease-resistant prion protein. Nature 1994; 370:471 - 4; http://dx.doi.org/10.1038/370471a0; PMID: 7913989
  • Kocisko DA, Priola SA, Raymond GJ, Chesebro B, Lansbury PT Jr., Caughey B. Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier. Proc Natl Acad Sci U S A 1995; 92:3923 - 7; http://dx.doi.org/10.1073/pnas.92.9.3923; PMID: 7732006
  • Saborio GP, Permanne B, Soto C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 2001; 411:810 - 3; http://dx.doi.org/10.1038/35081095; PMID: 11459061
  • Castilla J, Saá P, Hetz C, Soto C. In vitro generation of infectious scrapie prions. Cell 2005; 121:195 - 206; http://dx.doi.org/10.1016/j.cell.2005.02.011; PMID: 15851027
  • Lucassen R, Nishina K, Supattapone S. In vitro amplification of protease-resistant prion protein requires free sulfhydryl groups. Biochemistry 2003; 42:4127 - 35; http://dx.doi.org/10.1021/bi027218d; PMID: 12680767
  • Telling GC, Scott M, Mastrianni J, Gabizon R, Torchia M, Cohen FE, DeArmond SJ, Prusiner SB. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell 1995; 83:79 - 90; http://dx.doi.org/10.1016/0092-8674(95)90236-8; PMID: 7553876
  • Kaneko K, Zulianello L, Scott M, Cooper CM, Wallace AC, James TL, Cohen FE, Prusiner SB. Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation. Proc Natl Acad Sci U S A 1997; 94:10069 - 74; http://dx.doi.org/10.1073/pnas.94.19.10069; PMID: 9294164
  • Zulianello L, Kaneko K, Scott M, Erpel S, Han D, Cohen FE, Prusiner SB. Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein. J Virol 2000; 74:4351 - 60; http://dx.doi.org/10.1128/JVI.74.9.4351-4360.2000; PMID: 10756050
  • Perrier V, Kaneko K, Safar J, Vergara J, Tremblay P, DeArmond SJ, Cohen FE, Prusiner SB, Wallace AC. Dominant-negative inhibition of prion replication in transgenic mice. Proc Natl Acad Sci U S A 2002; 99:13079 - 84; http://dx.doi.org/10.1073/pnas.182425299; PMID: 12271119
  • Lee CI, Yang Q, Perrier V, Baskakov IV. The dominant-negative effect of the Q218K variant of the prion protein does not require protein X. Protein Sci 2007; 16:2166 - 73; http://dx.doi.org/10.1110/ps.072954607; PMID: 17766375
  • Geoghegan JC, Miller MB, Kwak AH, Harris BT, Supattapone S. Trans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactor. PLoS Pathog 2009; 5:e1000535; http://dx.doi.org/10.1371/journal.ppat.1000535; PMID: 19649330
  • Deleault NR, Harris BT, Rees JR, Supattapone S. Formation of native prions from minimal components in vitro. Proc Natl Acad Sci U S A 2007; 104:9741 - 6; http://dx.doi.org/10.1073/pnas.0702662104; PMID: 17535913
  • Deleault NR, Geoghegan JC, Nishina K, Kascsak R, Williamson RA, Supattapone S. Protease-resistant prion protein amplification reconstituted with partially purified substrates and synthetic polyanions. J Biol Chem 2005; 280:26873 - 9; http://dx.doi.org/10.1074/jbc.M503973200; PMID: 15917229
  • Geoghegan JC, Valdes PA, Orem NR, Deleault NR, Williamson RA, Harris BT, Supattapone S. Selective incorporation of polyanionic molecules into hamster prions. J Biol Chem 2007; 282:36341 - 53; http://dx.doi.org/10.1074/jbc.M704447200; PMID: 17940287
  • Nishina K, Deleault NR, Lucassen RW, Supattapone S. In vitro prion protein conversion in detergent-solubilized membranes. Biochemistry 2004; 43:2613 - 21; http://dx.doi.org/10.1021/bi035889l; PMID: 14992599
  • Nishina KA, Deleault NR, Mahal SP, Baskakov I, Luhrs T, Riek R, Supattapone S. The stoichiometry of host PrPC glycoforms modulates the efficiency of PrPSc formation in vitro. Biochemistry 2006; 45:14129 - 39; http://dx.doi.org/10.1021/bi061526k; PMID: 17115708
  • Barria MA, Mukherjee A, Gonzalez-Romero D, Morales R, Soto C. De novo generation of infectious prions in vitro produces a new disease phenotype. PLoS Pathog 2009; 5:e1000421; http://dx.doi.org/10.1371/journal.ppat.1000421; PMID: 19436715
  • Wang F, Wang X, Ma J. Conversion of bacterially expressed recombinant prion protein. Methods 2011; 53:208 - 13; http://dx.doi.org/10.1016/j.ymeth.2010.12.013; PMID: 21176786
  • Castilla J, Morales R, Saá P, Barria M, Gambetti P, Soto C. Cell-free propagation of prion strains. EMBO J 2008; 27:2557 - 66; http://dx.doi.org/10.1038/emboj.2008.181; PMID: 18800058
  • Deleault NR, Kascsak R, Geoghegan JC, Supattapone S. Species-dependent differences in cofactor utilization for formation of the protease-resistant prion protein in vitro. Biochemistry 2010; 49:3928 - 34; http://dx.doi.org/10.1021/bi100370b; PMID: 20377181
  • Deleault NR, Piro JR, Walsh DJ, Wang F, Ma J, Geoghegan JC, Supattapone S. Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids. Proc Natl Acad Sci U S A 2012; 109:8546 - 51; http://dx.doi.org/10.1073/pnas.1204498109; PMID: 22586108
  • Deleault NR, Walsh DJ, Piro JR, Wang F, Wang X, Ma J, Rees JR, Supattapone S. Cofactor molecules maintain infectious conformation and restrict strain properties in purified prions. Proc Natl Acad Sci U S A 2012; 109:E1938 - 46; http://dx.doi.org/10.1073/pnas.1206999109; PMID: 22711839
  • Bruce ME. Scrapie strain variation and mutation. Br Med Bull 1993; 49:822 - 38; PMID: 8137131
  • Carlson GA. Prion strains. Curr Top Microbiol Immunol 1996; 207:35 - 47; http://dx.doi.org/10.1007/978-3-642-60983-1_4; PMID: 8575205
  • Piro JR, Harris BT, Nishina K, Soto C, Morales R, Rees JR, Supattapone S. Prion protein glycosylation is not required for strain-specific neurotropism. J Virol 2009; 83:5321 - 8; http://dx.doi.org/10.1128/JVI.02502-08; PMID: 19297485
  • Wang F, Wang X, Yuan CG, Ma J. Generating a prion with bacterially expressed recombinant prion protein. Science 2010; 327:1132 - 5; http://dx.doi.org/10.1126/science.1183748; PMID: 20110469
  • Saá P, Sferrazza GF, Ottenberg G, Oelschlegel AM, Dorsey K, Lasmézas CI. Strain-specific role of RNAs in prion replication. J Virol 2012; 86:10494 - 504; http://dx.doi.org/10.1128/JVI.01286-12; PMID: 22811520
  • Gonzalez-Montalban N, Lee YJ, Makarava N, Savtchenko R, Baskakov IV. Changes in prion replication environment cause prion strain mutation. FASEB J 2013; 27:3702 - 10; http://dx.doi.org/10.1096/fj.13-230466; PMID: 23729586
  • Fernández-Borges N, Eraña H, Elezgarai SR, Harrathi C, Gayosso M, Castilla J. Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like Mechanism. Int J Cell Biol 2013; 2013:583498; http://dx.doi.org/10.1155/2013/583498; PMID: 24187553
  • Brown P, Gibbs CJ Jr., Rodgers-Johnson P, Asher DM, Sulima MP, Bacote A, Goldfarb LG, Gajdusek DC. Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease. Ann Neurol 1994; 35:513 - 29; http://dx.doi.org/10.1002/ana.410350504; PMID: 8179297
  • Brown P, Preece M, Brandel JP, Sato T, McShane L, Zerr I, Fletcher A, Will RG, Pocchiari M, Cashman NR, et al. Iatrogenic Creutzfeldt-Jakob disease at the millennium. Neurology 2000; 55:1075 - 81; http://dx.doi.org/10.1212/WNL.55.8.1075; PMID: 11071481

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