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Research Paper

Quantitative and qualitative analysis of cellular prion protein (PrPC) expression in bovine somatic tissues

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Pages 161-170 | Received 04 May 2009, Accepted 07 Aug 2009, Published online: 01 Jul 2009

References

  • McKinley MP, Taraboulos A, Kenaga L, Serban D, Stieber A, DeArmond SJ, et al. Ultrastructural localization of scrapie prion proteins in cytoplasmic vesicles of infected cultured cells. Lab Invest 1991; 65:622 - 630
  • Caughey BW, Dong A, Bhat KS, Ernst D, Hayes SF, Caughey WS. Secondary structure analysis of the scrapie-associated protein PrP 27–30 in water by infrared spectroscopy. Biochemistry 1991; 30:7672 - 7680
  • Pan KM, Baldwin M, Nguyen J, Gasset M, Serban A, Groth D, et al. Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc Natl Acad Sci USA 1993; 90:10962 - 10966
  • Prusiner SB. Novel proteinaceous infectious particles cause scrapie. Science 1982; 216:136 - 144
  • Prusiner SB. Prions. Proc Natl Acad Sci USA 1998; 95:13363 - 13383
  • Bueler H, Aguzzi A, Sailer A, Greiner RA, Autenried P, Aguet M, et al. Mice devoid of PrP are resistant to scrapie. Cell 1993; 73:1339 - 1347
  • Collinge J. Prion diseases of humans and animals: their causes and molecular basis. Annu Rev Neurosci 2001; 24:519 - 550
  • Milhavet O, Lehmann S. Oxidative stress and the prion protein in transmissible spongiform encephalopathies. Brain Res Rev 2002; 38:328 - 339
  • Roucou X, Giannopoulos PN, Zhang Y, Jodoin J, Goodyer CG, LeBlanc A. Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells. Cell Death Differ 2005; 12:783 - 795
  • Mouillet-Richard S, Ermonval M, Chebassier C, Laplanche JL, Lehmann S, Launay JM, et al. Signal transduction through prion protein. Science 2000; 289:1925 - 1928
  • Schneider B, Mutel V, Pietri M, Ermonval M, Mouillet-Richard S, Kellermann O. NADPH oxidase and extracellular regulated kinases ½ are targets of prion protein signaling in neuronal and nonneuronal cells. Proc Natl Acad Sci USA 2003; 100:13326 - 13331
  • Steele AD, Emsley JG, Ozdinler PH, Lindquist S, Macklis J. Prion protein (PrPC) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis. Proc Natl Acad Sci USA 2006; 103:3416 - 3421
  • Bueler H, Raeber A, Sailer A, Fischer M, Aguzzi A, Weissmann C. High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene. Mol Med 1994; 1:19 - 30
  • Fischer M, Rulicke T, Raeber A, Sailer A, Moser M, Oesch B, et al. Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J 1996; 15:1255 - 1264
  • Bendheim PE, Brown HR, Rudelli RD, Scala LJ, Goller NL, Wen GY, et al. Nearly ubiquitous tissue distribution of the scrapie agent precursor protein. Neurology 1992; 42:149 - 156
  • Ford MJ, Burton LJ, Morris RJ, Hall SM. Selective expression of prion protein in peripheral tissues of the adult mouse. Neuroscience 2002; 113:177 - 192
  • Horiuchi M, Yamazaki N, Ikeda T, Ishiguro N, Shinagawa M. A cellular form of prion protein (PrPC) exists in many non-neuronal tissues of sheep. J Gen Virol 1995; 76:2583 - 2587
  • Tichopad A, Pfaffl MW, Didier A. Tissue-specific expression pattern of bovine prion gene: quantification using real-time RT-PCR. Mol Cell Probes 2003; 17:5 - 10
  • Bruce ME, Will RG, Ironside JW, McConnell I, Drummond D, Suttie A, et al. Transmissions to mice indicate that ‘new variant’ CJD is caused by the BSE agent. Nature 1997; 389:498 - 501
  • Diaz-San Segundo F, Salguero FJ, de Avila A, Espinosa JC, Torres JM, Brun A. Distribution of the cellular prion protein (PrPC) in brains of livestock and domesticated species. Acta Neuropathol 2006; 112:587 - 595
  • Espinosa JMM, Castilla JRM, Torres J. Progression of prion infectivity in asymptomatic cattle after oral bovine spongiform encephalopathy challenge. J Gen Virol 2007; 88:1379 - 1383
  • Iwata N, Sato Y, Higuchi Y, Nohtomi K, Nagata N, Hasegawa H, et al. Distribution of PrPSc in cattle with bovine spongiform encephalopathy slaughtered at abattoirs in Japan. Jpn J Infect Dis 2006; 59:100 - 107
  • Terry LA, Marsh S, Ryder SJ, Hawkins SA, Wells GA, Spencer YI. Detection of disease-specific PRP in the distal ileum of cattle exposed orally to the agent of bovine spongiform encephalopathy. Vet Rec 2003; 152:387 - 392
  • Courageot M, Daude N, Nonno R, Paquet S, Di Bari M, Le Dur A, et al. A cell line infectible by prion strains from different species. J Gen Virol 2008; 2008:341 - 347
  • USDA, United States Department of Agriculture. Prohibition of the use of specified risk materials for human food and requirements for the disposition of non-ambulatory disabled cattle. Food Safety and Inspection Service. 9 Federal Register 2007; 72:38700 - 38730
  • Wells GAH, Hancock RD, Cooley WA, Richards MS. Bovine spongiform encephalopathy: diagnostic significance of vacuolar changes in selected nuclei of the medulla oblongata. Vet Rec 1989; 125:521 - 524
  • Ford M, Burton L, Graham C, Frobert Y, Grassi J, Hall S, et al. A marked disparity between the expression of prion protein and its message by neurons of the CNS. Neuroscience 2002; 111:5333 - 5551
  • Kubosaki A, Yusa S, Nasu Y, Nishimura T, Nakamura Y, Saeki K, et al. Distribution of cellular isoform of prion protein in T lymphocytes and bone marrow, analyzed by wild-type and prion protein gene-deficient mice. Biochem Biophys Res Commun 2001; 282:103 - 107
  • Liu T, Li R, Wong B, Liu D, Pan T, Petersen R, et al. Normal cellular prion protein is preferentially expressed on subpopulations of murine hemopoietic cells. J Immunol 2001; 166:3733 - 3742
  • Muramoto T, Kitamoto T, Tateishi J, Goto I. The sequential development of abnormal prion protein accumulation in mice with Creutzfeldt-Jakob disease. Am J Pathol 1992; 140:1411 - 1420
  • Andreoletti O, Morel N, Lacroux C, Rouillon V, Barc C, Tabouret G, et al. Bovine spongiform encephalopathy agent in spleen from an ARR/ARR orally exposed sheep. J Gen Virol 2006; 87:1043 - 1046
  • Miyazawa K, Kanaya T, Tanaka S, Takakura I, Watanabe K, Ohwada S, et al. Immunohistochemical characterization of cell types expressing the cellular prion protein in the small intestine of cattle and mice. Histochem Cell Biol 2007; 127:291 - 301
  • van Keulen LJ, Schreuder BE, Vromans ME, Langeveld JP, Smits MA. Scrapie-associated prion protein in the gastrointestinal tract of sheep with scrapie. J Comp Pathol 1999; 121:55 - 63
  • Klein MA, Frigg R, Raeber AJ, Flechsig E, Hegyi I, Zinkernagel RM, et al. PrP expression in B lymphocytes is not required for prion neuroinvasion. Nat Med 1998; 4:1429 - 1433
  • Thielen C, Melot F, Jolois O, Leclercq F, Tsunoda R, Frobert Y, et al. Isolation of bovine follicular dendritic cells allows the demonstration of a particular cellular prion protein. Cell Tissue Res 2001; 306:49 - 55
  • Mabbot NA, Mackay F, Minns F, Bruce ME. Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie. Nat Med 2000; 6:719 - 720
  • Terry LA, Marsh S, Ryder SJ, Hawkins SA, Wells GA, Spencer YI. Detection of disease-specific PRP in the distal ileum of cattle exposed orally to the agent of bovine spongiform encephalopathy. Vet Rec 2003; 152:387 - 392
  • Amselgruber WM, Buttner M, Schlegel T, Schweiger M, Pfaff E. The normal cellular prion protein (PrPC) is strongly expressed in bovine endocrine pancreas. Histochem Cell Biol 2006; 125:441 - 448
  • Amselgruber WM, Steffl M, Didier A, Martbauer E, Pfaff E, Buttner M. Prion protein expression in bovine podocytes and extraglomerular mesangial cells. Cell Tissue Res 2006; 324:497 - 505
  • Shaked GM, Shaked Y, Kariv-Inbal Z, Halimi M, Avraham I, Gabizon R. A protease-resistant prion protein isoform is present in urine of animals and humans affected with prion disease. J Biol Chem 2001; 276:31479 - 31482
  • Pammer J, Weninger W, Tschachler E. Human keratinocytes express cellular prion-related protein in vitro and during inflammatory skin diseases. Am J Pathol 1998; 153:1353 - 1358
  • Thomzig A, Schulz-Schaeffer W, Wrede A, Wemheuer W, Brenig B, Kratzel C, et al. Accumulation of pathological prion protein PrPSc in the skin of animals with experimental and natural scrapie. PLoS Pathog 2007; 3:66

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