Photodegradation illuminates the role of polyanions in prion infectivity

References

• Legname G, Baskakov IV, Nguyen HO, Riesner D, Cohen FE, DeArmond SJ, et al. Synthetic mammalian prions. Science 2004; 305:673 - 676
   PubMed Web of Science ®Google Scholar
• Colby DW, Wain R, Baskakov IV, Legname G, Palmer CG, Nguyen HO, et al. Protease-sensitive synthetic prions. PLoS Pathog 6:1000736
   Web of Science ®Google Scholar
• Kim JI, Cali I, Surewicz K, Kong Q, Raymond GJ, Atarashi R, et al. Mammalian prions generated from bacterially expressed prion protein in the absence of any mammalian cofactors. J Biol Chem 2010; 285:14083 - 14087
   PubMed Web of Science ®Google Scholar
• Makarava N, Kovacs GG, Bocharova O, Savtchenko R, Alexeeva I, Budka H, et al. Recombinant prion protein induces a new transmissible prion disease in wild-type animals. Acta Neuropathol 2010; 119:177 - 187
   PubMed Web of Science ®Google Scholar
• Deleault NR, Lucassen RW, Supattapone S. RNA molecules stimulate prion protein conversion. Nature 2003; 425:717 - 720
   PubMed Web of Science ®Google Scholar
• Deleault NR, Geoghegan JC, Nishina K, Kascsak R, Williamson RA, Supattapone S. Protease-resistant prion protein amplification reconstituted with partially purified substrates and synthetic polyanions. J Biol Chem 2005; 280:26873 - 26879
   PubMed Web of Science ®Google Scholar
• Deleault NR, Harris BT, Rees JR, Supattapone S. Formation of native prions from minimal componenets in vitro. Proc Natl Acad Sci USA 2007; 104:9741 - 9746
   PubMed Web of Science ®Google Scholar
• Geoghegan JC, Valdes PA, Orem NR, Deleault NR, Williamson RA, Harris BT, et al. Selective incorporation of polyanionic molecules into hamster prions. J Biol Chem 2007; 282:36341 - 36353
   PubMed Web of Science ®Google Scholar
• Wang F, Wang X, Yuan CG, Ma J. Generating a prion with bacterially expressed recombinant prion protein. Science 2010; 327:1132 - 1135
   PubMed Web of Science ®Google Scholar
• Wong C, Xiong LW, Horiuchi M, Raymond L, Wehrly K, Chesebro B, et al. Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein. EMBO J 2001; 20:377 - 386
   PubMed Web of Science ®Google Scholar
• Shaked GM, Meiner Z, Avraham I, Taraboulos A, Gabizon R. Reconstitution of prion infectivity from solubilized protease-resistant PrP and nonprotein components of prion rods. J Biol Chem 2001; 276:14324 - 14328
   PubMed Web of Science ®Google Scholar
• Ben-Zaken O, Tzaban S, Tal Y, Horonchik L, Esko JD, Vlodavsky I, et al. Cellular heparan sulfate participates in the metabolism of prions. J Biol Chem 2003; 278:40041 - 40049
   PubMed Web of Science ®Google Scholar
• Warner RG, Hundt C, Weiss S, Turnbull JE. Identification of the heparan sulfate binding sites in the cellular prion protein. J Biol Chem 2002; 277:18421 - 18430
   PubMed Web of Science ®Google Scholar
• Caughey B, Brown K, Raymond GJ, Katzenstein GE, Thresher W. Binding of the protease-sensitive form of PrP (prion protein) to sulfated glycosaminoglycan and congo red [corrected]. J Virol 1994; 68:2135 - 2141
   PubMed Web of Science ®Google Scholar
• Kocisko DA, Come JH, Priola SA, Chesebro B, Raymond GJ, Lansbury PT, et al. Cell-free formation of protease-resistant prion protein. Nature 1994; 370:471 - 474
   PubMed Web of Science ®Google Scholar
• Lucassen R, Nishina K, Supattapone S. In vitro amplification of protease-resistant prion protein requires free sulfhydryl groups. Biochemistry 2003; 42:4127 - 4135
   PubMed Web of Science ®Google Scholar
• Castilla J, Saa P, Hetz C, Soto C. In vitro generation of infectious scrapie prions. Cell 2005; 121:195 - 206
   PubMed Web of Science ®Google Scholar
• Saborio GP, Permanne B, Soto C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 2001; 411:810 - 813
   PubMed Web of Science ®Google Scholar
• Jeong BH, Kim NH, Jin JK, Choi JK, Lee YJ, Kim JI, et al. Reduction of prion infectivity and levels of scrapie prion protein by lithium aluminum hydride: implications for RNA in prion diseases. J Neuropathol Exp Neurol 2009; 68:870 - 879
   PubMed Web of Science ®Google Scholar
• Piro JR, Harris BT, Supattapone S. In situ photodegradation of incorporated polyanion does not alter prion infectivity. PLoS Pathog 2011; 7:1002001
   Web of Science ®Google Scholar
• Deleault NR, Kascsak R, Geoghegan JC, Supattapone S. Species-dependent differences in cofactor utilization for formation of the protease-resistant prion protein in vitro. Biochemistry 2010; 49:3928 - 3934
   PubMed Web of Science ®Google Scholar