459
Views
2
CrossRef citations to date
0
Altmetric
Commentary & View

Tracking protein aggregate interactions

, &
Pages 52-55 | Received 21 Mar 2011, Accepted 27 Apr 2011, Published online: 01 Apr 2011

References

  • Sawaya MR, Sambashivan S, Nelson R, Ivanova MI, Sievers SA, Apostol MI, et al. Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature 2007; 447:453 - 457
  • Eanes E, Glenner GG. X-ray diffraction studies on amyloid filaments. J Histochem Cytochem 1968; 16:673 - 677
  • Makarava N, Ostapchenko VG, Savtchenko R, Baskakov IV. Conformational switching within individual amyloid fibrils. J Biol Chem 2009; 284:14386 - 14395
  • Aguzzi A, Heikenwalder M, Polymenidou M. Insights into prion strains and neurotoxicity. Nat Rev Mol Cell Biol 2007; 8:552 - 561
  • Telling GC, Parchi P, DeArmond SJ, Cortelli P, Montagna P, Gabizon R, et al. Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science 1996; 274:2079 - 2082
  • Bessen RA, Marsh RF. Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent. J Virol 1992; 66:2096 - 2101
  • Bruce ME, McConnell I, Fraser H, Dickinson AG. The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis. J Gen Virol 1991; 72:595 - 603
  • Puoti G, Giaccone G, Rossi G, Canciani B, Bugiani O, Tagliavini F. Sporadic Creutzfeldt-Jakob disease: co-occurrence of different types of PrP(Sc) in the same brain. Neurology 1999; 53:2173 - 2176
  • Polymenidou M, Stoeck K, Glatzel M, Vey M, Bellon A, Aguzzi A. Coexistence of multiple PrPSc types in individuals with Creutzfeldt-Jakob disease. Lancet Neurol 2005; 4:805 - 814
  • Uro-Coste E, Cassard H, Simon S, Lugan S, Bilheude JM, Perret-Liaudet A, et al. Beyond PrP res type 1/type 2 dichotomy in Creutzfeldt-Jakob disease. PLoS Pathog 2008; 4:1000029
  • Cali I, Castellani R, Alshekhlee A, Cohen Y, Blevins J, Yuan J, et al. Co-existence of scrapie prion protein types 1 and 2 in sporadic Creutzfeldt-Jakob disease: its effect on the phenotype and prion-type characteristics. Brain 2009; 132:2643 - 2658
  • Kobayashi A, Mizukoshi K, Iwasaki Y, Miyata H, Yoshida Y, Kitamoto T. Co-occurrence of types 1 and 2 PrP(res) in sporadic Creutzfeldt-Jakob disease MM1. Am J Pathol 178:1309 - 1315
  • Kimberlin RH, Walker CA. Evidence that the transmission of one source of scrapie agent to hamsters involves separation of agent strains from a mixture. J Gen Virol 1978; 39:487 - 496
  • Mahal SP, Browning S, Li J, Suponitsky-Kroyter I, Weissmann C. Transfer of a prion strain to different hosts leads to emergence of strain variants. Proc Natl Acad Sci USA 107:22653 - 22658
  • Angers RC, Kang HE, Napier D, Browning S, Seward T, Mathiason C, et al. Prion strain mutation determined by prion protein conformational compatibility and primary structure. Science 328:1154 - 1158
  • Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, et al. Continuous quinacrine treatment results in the formation of drug-resistant prions. PLoS Pathog 2009; 5:1000673
  • Dickinson AG, Fraser H, McConnell I, Outram GW, Sales DI, Taylor DM. Extraneural competition between different scrapie agents leading to loss of infectivity. Nature 1975; 253:556
  • Dickinson AG, Fraser H, Meikle VM, Outram GW. Competition between different scrapie agents in mice. Nat New Biol 1972; 237:244 - 245
  • Bartz JC, Aiken JM, Bessen RA. Delay in onset of prion disease for the HY strain of transmissible mink encephalopathy as a result of prior peripheral inoculation with the replication-deficient DY strain. J Gen Virol 2004; 85:265 - 273
  • Manuelidis L. Vaccination with an attenuated Creutzfeldt-Jakob disease strain prevents expression of a virulent agent. Proc Natl Acad Sci USA 1998; 95:2520 - 2525
  • Manuelidis L, Lu ZY. Virus-like interference in the latency and prevention of Creutzfeldt-Jakob disease. Proc Natl Acad Sci USA 2003; 100:5360 - 5365
  • Schutt CR, Bartz JC. Prion interference with multiple prion isolates. Prion 2008; 2:61 - 63
  • Pattison IH. The relative susceptibility of sheep, goats and mice to two types of the goat scrapie agent. Res Vet Sci 1966; 7:207 - 212
  • Bartz JC, Bessen RA, McKenzie D, Marsh RF, Aiken JM. Adaptation and selection of prion protein strain conformations following interspecies transmission of transmissible mink encephalopathy. J Virol 2000; 74:5542 - 5547
  • Collinge J, Clarke AR. A general model of prion strains and their pathogenicity. Science 2007; 318:930 - 936
  • Li J, Browning S, Mahal SP, Oelschlegel AM, Weissmann C. Darwinian evolution of prions in cell culture. Science 2009; 327:869 - 872
  • Shikiya RA, Ayers JI, Schutt CR, Kincaid AE, Bartz JC. Co-infecting prion strains compete for a limiting cellular resource. J Virol 2010; 84:5706 - 5714
  • Kimberlin RH, Walker CA. Competition between strains of scrapie depends on the blocking agent being infectious. Intervirology 1985; 23:74 - 81
  • Dickinson AGaO GW. Prusiner SBaH WJ. The scrapie replication-site hypothesis and its implications for pathogenesis. Slow transmissible diseases of the central nervous system 1979; New York Academic Press 13 - 31
  • Bartz JC, Kramer ML, Sheehan MH, Hutter JA, Ayers JI, Bessen RA, et al. Prion interference is due to a reduction in strain-specific PrPSc levels. J Virol 2007; 81:689 - 697
  • Ayers JI, Kincaid AE, Bartz JC. Prion strain targeting independent of strain-specific neuronal tropism. J Virol 2009; 83:81 - 87
  • Ayers JI, Schutt CR, Shikiya RA, Aguzzi A, Kincaid AE, Bartz JC. The strain-encoded relationship between PrPSc replication, stability and processing in neurons is predictive of the incubation period of disease. PLoS Pathog 2011; 7:e1001317
  • Caughey B, Raymond GJ. Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells. J Virol 1993; 67:643 - 650
  • Deleault NR, Harris BT, Rees JR, Supattapone S. Formation of native prions from minimal components in vitro. Proc Natl Acad Sci USA 2007; 104:9741 - 9746
  • Geoghegan JC, Valdes PA, Orem NR, Deleault NR, Williamson RA, Harris BT, et al. Selective incorporation of polyanionic molecules into hamster prions. J Biol Chem 2007; 282:36341 - 36353
  • Kim JI, Surewicz K, Gambetti P, Surewicz WK. The role of glycophosphatidylinositol anchor in the amplification of the scrapie isoform of prion protein in vitro. FEBS Lett 2009; 583:3671 - 3675
  • Nilsson KP, Rydberg J, Baltzer L, Inganas O. Self-assembly of synthetic peptides control conformation and optical properties of a zwitterionic polythiophene derivative. Proc Natl Acad Sci USA 2003; 100:10170 - 10174
  • Nilsson KPR, Hammarstrom P, Ahlgren F, Herland A, Schnell EA, Lindgren M, et al. Conjugated polyelectrolytes-conformation-sensitive optical probes for staining and characterization of amyloid deposits. Chembiochem 2006; 7:1096 - 1104
  • Nilsson KPR, Andersson MR, Inganas O. Conformational transitions of a free amino-acid-functionalized polythiophene induced by different buffer systems. J Phys Condens Matter 2002; 14:10011 - 10020
  • Nilsson KP, Joshi-Barr S, Winson O, Sigurdson CJ. Prion strain interactions are highly selective. J Neurosci 2010; 30:12094 - 12102
  • Sigurdson CJ, Nilsson KP, Hornemann S, Manco G, Polymenidou M, Schwarz P, et al. Prion strain discrimination using luminescent conjugated polymers. Nat Methods 2007; 4:1023 - 1030
  • Nilsson KP, Aslund A, Berg I, Nystrom S, Konradsson P, Herland A, et al. Imaging distinct conformational states of amyloid-beta fibrils in Alzheimer's disease using novel luminescent probes. ACS Chem Biol 2007; 2:553 - 560
  • Sigurdson CJ, Nilsson KP, Hornemann S, Manco G, Fernandez-Borges N, Schwarz P, et al. A molecular switch controls interspecies prion disease transmission in mice. J Clin Invest 2010; 120:2590 - 2599
  • Sigurdson CJ, Nilsson KP, Hornemann S, Heikenwalder M, Manco G, Schwarz P, et al. De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis. Proc Natl Acad Sci USA 2009; 106:304 - 309
  • Nilsson KP, Ikenberg K, Aslund A, Fransson S, Konradsson P, Rocken C, et al. Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy. Am J Pathol 2010; 176:563 - 574
  • Derkatch IL, Uptain SM, Outeiro TF, Krishnan R, Lindquist SL, Liebman SW. Effects of Q/N-rich, polyQ and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro. Proc Natl Acad Sci USA 2004; 101:12934 - 12939
  • Derkatch IL, Liebman SW. Prion-prion interactions. Prion 2007; 1:161 - 169
  • Rajan RS, Illing ME, Bence NF, Kopito RR. Specificity in intracellular protein aggregation and inclusion body formation. Proc Natl Acad Sci USA 2001; 98:13060 - 13065
  • Aslund A, Sigurdson CJ, Klingstedt T, Grathwohl S, Bolmont T, Dickstein DL, et al. Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses. ACS Chem Biol 2009; 4:673 - 684

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.