Is a metabolic enzyme complex involved in the efficient and accurate control of Ipecac alkaloid biosynthesis in Psychotria ipecacuanha?

References

• Janot M-M. Manske RHF, Holmes HL. The ipecac alkaloids. The Alkaloids 1953; 3:San Diego Academic Press 363 - 394
   Google Scholar
• Fujii T, Ohba M. Cordel GA. The Alkaloids 1998; 51:San Diego Academic Press 271 - 321
   Google Scholar
• Wiegrebe W, Kramer WJ, Shamma M. The emetine alkaloids. J Nat Prod 1984; 47:397 - 408
   Web of Science ®Google Scholar
• Nomura T, Quesada AL, Kutchan TM. The new β-D-glucosidase in terpenoid-isoquinoline alkaloid biosynthesis in Psychotria ipecacuanha. J Biol Chem 2008; 283:34650 - 34659
   PubMed Web of Science ®Google Scholar
• Nomura T, Kutchan TM. Three new O-methyltransferases are sufficient for all O-methylation reactions of ipecac alkaloid biosynthesis in root culture of Psychotria ipecacuanha. J Biol Chem 2010; 285:7722 - 7738
   PubMed Web of Science ®Google Scholar
• Ziegler J, Diaz-Cháves ML, Kramell R, Ammer C, Kutchan TM. Comparative macroarray analysis of morphine containing Papaver somniferum and eight morphine free Papaver species identifies an O-methyltransferase involved in benzylisoquinoline biosynthesis. Planta 2005; 222:458 - 471
   PubMed Web of Science ®Google Scholar
• Ziegler J, Voigtländer S, Schmidt J, Kramell R, Miersch O, Ammer C, et al. Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis. Plant J 2006; 48:177 - 192
   PubMed Web of Science ®Google Scholar
• Liscombe DK, Facchini PJ. Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy. J Biol Chem 2007; 282:14741 - 14751
   PubMed Web of Science ®Google Scholar
• Pienkny S, Brandt W, Schmidt J, Kramell R, Ziegler J. Functional characterization of a novel benzylisoquinoline O-methyltransferase suggests its involvement in papaverine biosynthesis in opium poppy (Papaver somniferum L). Plant J 2009; 60:56 - 67
   PubMed Web of Science ®Google Scholar
• Minami H, Dubouzet E, Iwasa K, Sato F. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem 2007; 282:6274 - 6282
   PubMed Web of Science ®Google Scholar
• Morishige T, Dubouzet E, Choi K-B, Yazaki K, Sato F. Molecular cloning of columbamine O-methyltransferase from cultured Coptis japonica cells. Eur J Biochem 2002; 269:5659 - 5667
   PubMedGoogle Scholar
• Srere PA. Complexes of sequential metabolic enzymes. Ann Rev Biochem 1987; 56:89 - 124
   PubMed Web of Science ®Google Scholar
• Ovádi J, Srere PA. Macromolecular compartmentation and channeling. Int Rev Cytol 2000; 192:255 - 279
   PubMed Web of Science ®Google Scholar
• Panicot M, Minguet EG, Ferrando A, Alcázar R, Blázquez MA, Carbonell J, et al. A polyamine metabolon involving aminopropyl transferase complexes in Arabidopsis. Plant Cell 2002; 14:2539 - 2551
   PubMed Web of Science ®Google Scholar
• Jørgensen K, Rasmussen AV, Morant M, Nielsen AH, Bjarnholt N, Zagrobelny M, et al. Metabolon formation and metabolic channeling in the biosynthesis of plant natural products. Curr Opin Plant Biol 2005; 8:280 - 291
   PubMed Web of Science ®Google Scholar
• Nielsen KA, Tattersall DB, Jones PR, Møller BL. Metabolon formation in dhurrin biosynthesis. Phytochemistry 2008; 69:88 - 98
   PubMed Web of Science ®Google Scholar
• Kempe K, Higashi Y, Frick S, Sabarna K, Kutchan TM. RNAi suppression of the morphine biosynthetic gene salAT and evidence of association of pathway enzymes. Phytochemistry 2009; 70:579 - 589
   PubMed Web of Science ®Google Scholar
• Roberts MF, McCarthy D, Kutchan TM, Coscia CJ. Localization of enzymes and alkaloidal metabolites in Papaver latex. Arch Biochem Biophys 1983; 222:599 - 609
   PubMed Web of Science ®Google Scholar
• Kutchan TM, Rush M, Coscia CJ. Subcellular localization of alkaloids and dopamine in different vacuolar compartments of Papaver bracteatum. Plant Physiol 1986; 81:161 - 166
   PubMed Web of Science ®Google Scholar
• McKnight TD, Bergey DR, Burnett RJ, Nessler CL. Expression and enzymatically active and correctly targeted strictosidine synthase in transgenic tobacco plants. Planta 1991; 185:148 - 152
   PubMed Web of Science ®Google Scholar
• Stevens LH, Blom TJM, Verpoorte R. Subcellular localization of tryptophan decarboxylase, strictosidine synthase and strictosidine β-D-glucosidase in suspension cultured cells of Catharanthus roseus and Tabernaemontata divaricata. Plant Cell Rep 1993; 12:573 - 576
   PubMed Web of Science ®Google Scholar