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Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis

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Pages 123-136 | Received 11 Apr 2011, Accepted 07 May 2011, Published online: 30 Jun 2011

References

  • Cheng CY, Mruk DD. A local autocrine axis in the testes that regulates spermatogenesis. Nat Rev Endocrinol 2010; 6:380 - 395; http://dx.doi.org/10.1038/nrendo.2010.71
  • Cheng CY, Mruk DD. Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development. Physiol Rev 2002; 82:825 - 874; http://dx.doi.org/10.1152/physrev.00009.200
  • Mruk DD, Cheng CY. Sertoli-Sertoli and Sertoligerm cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev 2004; 25:747 - 806; http://dx.doi.org/10.1210/er.2003-0022
  • O'Donnell L, Robertson KM, Jones ME, Simpson ER. Estrogen and spermatogenesis. Endocr Rev 2001; 22:289 - 318; http://dx.doi.org/10.1210/er.22.3.289
  • O'Donnell L, Meachem SJ, Stanton PG, McLachlan RI. Neill JD. Endocrine regulation of spermatogenesis. Physiology of Reproduction 2006; 3:Amsterdam Elsevier 1017 - 1069
  • Carreau S, Hess RA. Oestrogens and spermatogenesis. Philos Trans R Soc Lond B Biol Sci 2010; 365:1517 - 1535; http://dx.doi.org/10.1098/rstb.2009.0235
  • Carreau S, Wolczynski S, Galeraud-Denis I. Aromatase, estrogens and human male reproduction. Philos Trans R Soc Lond B Biol Sci 2010; 365:1571 - 1579; http://dx.doi.org/10.1098/rstb.2009.0113
  • Walker WH. Non-classical actions of testosterone and spermatogenesis. Philos Trans R Soc Lond B Biol Sci 2010; 365:1557 - 1569; http://dx.doi.org/10.1098/rstb.2009.0258
  • Sharpe RM. Knobil E, Neill JD. Regulation of spermatogenesis. The Physiology of Reproduction 1994; New York Raven Press 1363 - 1434
  • Hess RA. Estrogen in the adult male reproductive tract: A review. Reprod Biol Endocrinol 2003; 1:52; http://dx.doi.org/10.1186/1477-7827-1-52
  • Setchell BP. Cheng CY. Blood-testis barrier, junctional and transport proteins and spermatogenesis. Molecular Mechanisms in Spermatogenesis 2008; Austin TX Landes Bioscience/Springer Science+Business Media, LLC 212 - 233
  • Mruk DD, Silvestrini B, Cheng CY. Anchoring junctions as drug targets: Role in contraceptive development. Pharmacol Rev 2008; 60:146 - 180; http://dx.doi.org/10.1124/pr.107.07105
  • O'Donnell L, Nicholls PK, O'Bryan MK, McLachlan RI, Stanton PG. Spermiation: the process of sperm release. Spermatogenesis 2011; 1:14 - 35; http://dx.doi.org/10.4161/spmg.1.1.14525
  • Parvinen M. Regulation of the seminiferous epithelium. Endocr Rev 1982; 3:404 - 417; http://dx.doi.org/10.1210/edrv-3-4-404
  • Cheng CY, Mruk DD. Regulation of spermiogenesis, spermiation and blood-testis barrier dynamics: novel insights from studies on Eps8 and Arp3. Biochem J 2011; 435:553 - 562; http://dx.doi.org/10.1042/BJ20102121
  • Lie PPY, Mruk DD, Lee WM, Cheng CY. Cytoskeletal dynamics and spermatogenesis. Philos Trans R Soc Lond B Biol Sci 2010; 365:1581 - 1592; http://dx.doi.org/10.1098/rstb.2009.0261
  • Vogl AW. Distribution and function of organized concentrations of actin filaments in mammalian spermatogenic cells and Sertoli cells. Int Rev Cytol 1989; 119:1 - 56; http://dx.doi.org/10.1016/S0074-7696(08)60648-8
  • Vogl A, Vaid K, Guttman J. Cheng CY. The Sertoli cell cytoskeleton. Molecular Mechanisms in Spermatogenesis 2008; Austin TX Landes Bioscience/Springer Science+Business Media, LLC 186 - 211
  • Lie PPY, Mruk DD, Lee WM, Cheng CY. Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood-testis barrier integrity in the seminiferous epithelium. FASEB J 2009; 23:2555 - 2567; http://dx.doi.org/10.1096/fj.06-070573
  • Lie PPY, Chan AYN, Mruk DD, Lee WM, Cheng CY. Restricted Arp3 expression in the testis prevents bloodtestis barrier disruption during junction restructuring at spermatogenesis. Proc Natl Acad Sci USA 2010; 107:11411 - 14116; http://dx.doi.org/10.1073/pnas.1001823107
  • Hayashi K, et al. Domain analysis of the actin-binding and actin-remodeling activities of drebrin. Exp Cell Res 1999; 253:673 - 680; http://dx.doi.org/10.1006/excr.1999.4663
  • Shirao T, et al. Formation of thick, curving bundles of actin by drebrin A expressed in fibroblasts. Exp Cell Res 1994; 215:145 - 153; http://dx.doi.org/10.1006/excr.1994.1326
  • Lappalainen P, Kessels MM, Cope MJ, Drubin DG. The ADF homology (ADF-H) domain: a highly exploited actin-binding module. Mol Biol Cell 1998; 9:1951 - 1959
  • Shirao T. The roles of microfilament-associated proteins, drebrins, in brain morphogenesis: a review. J Biochem 1995; 117:231 - 236; http://dx.doi.org/10.1093/jb/117.2.231
  • Dun XP, Chilton JK. Control of cell shape and plasticity during development and disease by actin-binding protein Drebrin. Histol Histopathol 2010; 25:533 - 540
  • Majoul I, Shirao T, Sekino Y, Duden R. Many faces of drebrin: from building dendritic spines and stabilizing gap junctions to shaping neurite-like cell processes. Histochem Cell Biol 2007; 127:355 - 361; http://dx.doi.org/10.1007/s00418-007-0273-y
  • Peitsch WK, et al. Drebrin is a widespread actinassociating protein enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells. Eur J Cell Biol 1999; 78:767 - 778
  • Keon BH, Jedrzejewski PT, Paul DL, Goodenough DA. Isoform specific expression of the neuronal F-actin binding protein, drebrin, in specialized cells of stomach and kidney epithelia. J Cell Sci 2000; 113:325 - 336
  • Grintsevich EE, et al. Mapping of drebrin binding site on F-actin. J Mol Biol 2010; 398:542 - 554; http://dx.doi.org/10.1016/j.jmb.2010.03.039
  • Ishikawa R, et al. Drebrin, a development-associated brain protein from rat embryo, causes the dissociation of tropomyosin from actin filaments. J Biol Chem 1994; 269:29928 - 29933
  • Kessels MM, Engqvist-Goldstein AE, Drubin DG. Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation. Mol Biol Cell 2000; 11:393 - 412
  • Sekino Y, Kojima N, Shirao T. Role of actin cytoskeleton in dendritic spine morphogenesis. Neurochem Int 2007; 51:92 - 104; http://dx.doi.org/10.1016/j.neuint.2007.04.029.33
  • Cheng CY, Mruk DD. An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective. Crit Rev Biochem Mol Biol 2009; 44:245 - 263; http://dx.doi.org/10.1080/10409230903061207
  • Cheng CY, et al. AF-2364 [1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide] is a potential male contraceptive: a review of recent data. Contraception 2005; 72:251 - 261; http://dx.doi.org/10.1016/j.contraception.2005.03.008
  • Cheng CY, Mruk DD. New frontiers in non-hormonal male contraception. Contraception 2010; 82:476 - 482; http://dx.doi.org/10.1016/j.contraception.2010.03.017
  • Mok KW, Mruk DD, Lie PPY, Lui WY, Cheng CY. Adjudin, a potential male contraceptive, exerts its effects locally in the seminifeorus epithelium of mammalian testes. Reproduction 2011; 141:571 - 580; http://dx.doi.org/10.1530/REP-10-0464
  • Chen YM, Lee NPY, Mruk DD, Lee WM, Cheng CY. Fer kinase/Fer T and adherens junction dynamics in the testis: an in vitro and in vivo study. Biol Reprod 2003; 69:656 - 672; http://dx.doi.org/10.1095/biolreprod.103.016881
  • Li MWM, Mruk DD, Lee WM, Cheng CY. Connexin 43 and plakophilin-2 as a protein complex that regulates blood-testis barrier dynamics. Proc Natl Acad Sci USA 2009; 106:10213 - 10218; http://dx.doi.org/10.1073/pnas.0901700106
  • Cheng CY, et al. Two new male contraceptives exert their effects by depleting germ cells prematurely from the testis. Biol Reprod 2001; 65:449 - 461; http://dx.doi.org/10.1095/biolreprod65.2.449
  • Mok KW, Mruk DD, Lee WM, Cheng CY. Spermatogonial stem cells alone are not sufficient to re-initiate spermatogenesis in the rat testis following adjudin-induced infertility. Int J Androl 2011; In press http://dx.doi.org/10.1111/j.1365-2605.2010.01183.x.)
  • Siu MKY, Wong CH, Lee WM, Cheng CY. Sertoligerm cell anchoring junction dynamics in the testis are regulated by an interplay of lipid and protein kinases. J Biol Chem 2005; 280:25029 - 25047; http://dx.doi.org/10.1074/jbc.M501049200
  • Lee NPY, Cheng CY. Regulation of Sertoli cell tight junction dynamics in the rat testis via the nitric oxide synthase/soluble guanylate cyclase/3′,5′-cyclic guanosine monophosphate/protein kinase G signaling pathway: an in vitro study. Endocrinology 2003; 144:3114 - 3129; http://dx.doi.org/10.1210/en.2002-0167
  • Yan HHN, Mruk DD, Lee WM, Cheng CY. Bloodtestis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells. FASEB J 2008; 22:1945 - 1959; http://dx.doi.org/10.1096/fj.06-070342
  • Xia W, Wong EWP, Mruk DD, Cheng CY. TGFβ3 and TNFα perturb blood-testis barrier (BTB) dynamics by accelerating the clathrin-mediated endocytosis of integral membrane proteins: A new concept of BTB regulation during spermatogenesis. Dev Biol 2009; 327:48 - 61; http://dx.doi.org/10.1016/j.ydbio.2008.11.028
  • Su L, Mruk DD, Lee WM, Cheng CY. Differential effects of testosterone and TGFβ3 on endocytic vesicle-mediated protein trafficking events at the bloodtestis barrier. Exp Cell Res 2010; 316:2945 - 2960; http://dx.doi.org/10.1016/j.yexcr.2010.07.018
  • Lui WY, Lee WM, Cheng CY. Transforming growth factor-β3 perturbs the inter-Sertoli tight junction permeability barrier in vitro possibly mediated via its effects on occludin, zonula occludens-1 and claudin-11. Endocrinology 2001; 142:1865 - 1877; http://dx.doi.org/10.1210/en.142.5.1865
  • Lui WY, Lee WM, Cheng CY. Transforming growth factor-β3 regulates the dynamics of Sertoli cell tight junctions via the p38 mitogen-activated protein kinase pathway. Biol Reprod 2003; 68:1597 - 1612; http://dx.doi.org/10.1095/biolreprod.102.011387
  • Siu MKY, Lee WM, Cheng CY. The interplay of collagen IV, tumor necrosis factor-α, gelatinase B (matrix metalloprotease-9) and tissue inhibitor of metalloprotease-1 in the basal lamina regulates Sertoli cell-tight junction dynamics in the rat testis. Endocrinology 2003; 144:371 - 387; http://dx.doi.org/10.1210/en.2002-220786
  • Butkevich E, et al. Drebrin is a novel connexin-43 binding partner that links gap junctions to the submembrane cytoskeleton. Curr Biol 2004; 14:650 - 658; http://dx.doi.org/10.1016/j.cub.2004.03.063
  • Rottner K, Hanisch J, Campellone KG. WASH, WHAMM and JMY: regulation of Arp2/3 complex and beyond. Trends Cell Biol 2010; 20:650 - 661; http://dx.doi.org/10.1016/j.tcb.2010.08.014
  • Nurnberg A, Kitzing T, Grosse R. Nucleating actin for invasion. Nat Rev Cancer 2011; 11:177 - 187; http://dx.doi.org/10.1038/nrc3003
  • Ahmed S, Goh WI, Bu W. I-BAR domains, IRSp53 and filopodium formation. Semin Cell Dev Biol 2010; 21:350 - 356; http://dx.doi.org/10.1016/j.semcdb.2009.11.008
  • Mruk DD, Cheng CY. The myotubularin family of lipid phosphatases in disease and in spermatogenesis. Biochem J 2010; 433:253 - 262; http://dx.doi.org/10.1042/BJ20101267
  • Li MWM, Mruk DD, Lee WM, Cheng CY. Connexin 43 is critical to maintain the homeostasis of blood-testis barrier via its effects on tight junction reassembly. Proc Natl Acad Sci USA 2010; 107:17998 - 18003; http://dx.doi.org/10.1073/pnas.1007047107
  • Russell LD. Further observations on tubulobulbar complexes formed by late spermatids and Sertoli cells in the rat testis. Anat Rec 1979; 194:213 - 232; http://dx.doi.org/10.1002/ar.1091940204
  • Young JS, Guttman JA, Vaid KS, Vogl AW. Tubulobulbar complexes are intercellular podosomelike structures that internalize intact intercellular junctions during epithelial remodeling events in the rat testis. Biol Reprod 2009; 80:162 - 174; http://dx.doi.org/10.1095/biolreprod.108.070623
  • Young JS, Guttman JA, Vaid KS, Vogl AW. Cortactin (CTTN), N-WASP (WASL) and clathrin (CLTC) are present at podosome-like tubulobulbar complexes in the rat testis. Biol Reprod 2009; 80:153 - 161; http://dx.doi.org/10.1095/biolreprod.108.070615
  • Xia W, Mruk DD, Lee WM, Cheng CY. Cytokines and junction restructuring during spermatogenesis—a lesson to learn from the testis. Cytokine Growth Factor Rev 2005; 16:469 - 493; http://dx.doi.org/10.1016/j.cytogfr.2005.05.007
  • Zhao L, et al. Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease. Nat Neurosci 2006; 9:234 - 242; http://dx.doi.org/10.1038/nn1630
  • Kojima N, Shirao T. Synaptic dysfunction and disruption of postsynaptic drebrin.actin complex: A study of neurological disorders accompanied by cognitive deficits. Neurosci Res 2007; 58:1 - 5; http://dx.doi.org/10.1016/j.neures.2007.02.003
  • Siu MKY, Wong CH, Xia W, Mruk DD, Lee WM, Cheng CY. The ×1-integrin-p-FAK-p130Cas-DOCK180-RhoA-vinculin is a novel regulatory protein complex at the apical ectoplasmic specialization in adult rat testes. Spermatogenesis 2011; 1:73 - 86; http://dx.doi.org/10.4161/spmg.1.1.1545
  • Lui WY, Wong CH, Mruk DD, Cheng CY. TGFβ3 regulates the blood-testis barrier dynamics via the p38 mitogen activated protein (MAP) kinase pathway: an in vivo study. Endocrinology 2003; 144:1139 - 1142; http://dx.doi.org/10.1210/en.2002-0211
  • Lie PPY, Cheng CY, Mruk DD. Interleukin-1α is a regulator of the blood-testis barrier. FASEB J 2011; 25:1244 - 1253; http://dx.doi.org/10.1096/fj.10-169995
  • Sarkar O, Mathur PP, Cheng CY, Mruk DD. Interleukin 1alpha (IL1A) is a novel regulator of the blood-testis barrier in the rat. Biol Reprod 2008; 78:445 - 454; http://dx.doi.org/10.1095/biolreprod.107.064501
  • Wong EWP, Mruk DD, Lee WM, Cheng CY. Regulation of blood-testis barrier dynamics by TGFβ3 is a Cdc42-dependent protein trafficking event. Proc Natl Acad Sci USA 2010; 107:11399 - 11404; http://dx.doi.org/10.1073/pnas.1001077107
  • Russell L. Movement of spermatocytes from the basal to the adluminal compartment of the rat testis. Am J Anat 1977; 148:313 - 328; http://dx.doi.org/10.1002/aja.1001480303
  • Hess RA, de Franca LR. Cheng CY. Spermatogenesis and cycle of the seminiferous epithelium. Molecular Mechanisms in Spermatogenesis 2008; Austin, TX Landes Bioscience/Springer Science+Business Media, LLC 1 - 15
  • De SK, et al. Expression of tumor necrosis factor-α in mouse spermatogenic cells. Endocrinology 1993; 133:389 - 396; http://dx.doi.org/10.1210/en.133.1.389
  • Mullaney BP, Skinner M. Transforming growth factor-β (β1, β2 and β3) gene expression and action during pubertal development of the seminiferous tubule: potential role at the onset of spermatogenesis. Mol Endocrinol 1993; 7:67 - 76; http://dx.doi.org/10.1210/me.7.1.67
  • Xia W, Mruk DD, Lee WM, Cheng CY. Differential interactions between transforming growth factor-β3/TßR1, Tab1 and CD2AP disrupt blood-testis barrier and Sertoli-germ cell adhesion. J Biol Chem 2006; 281:16799 - 16813; http://dx.doi.org/10.1074/jbc.M601618200
  • Goicoechea SM, Arneman D, Otey CA. The role of palladin in actin organization and cell motility. Eur J Cell Biol 2008; 87:517 - 525; http://dx.doi.org/10.1016/j.ejcb.2008.01.010
  • Chin YR, Toker A. Akt2 regulates expression of the actin-bundling protein palladin. FEBS Lett 2010; 584:4769 - 4774; http://dx.doi.org/10.1016/j.febslet.2010.10.056
  • Cheng CY, Marther JP, Byer AL, Bardin CW. Identification of hormonally responsive proteins in primary Sertoli cell culture medium by anionexchange high performance liquid chromatography. Endocrinology 1986; 118:480 - 488; http://dx.doi.org/10.1210/endo-118-2-480
  • Li JCH, Lee WM, Mruk DD, Cheng CY. Regulation of Sertoli cell myotubularin (rMTM) expression by germ cells in vitro. J Androl 2001; 22:266 - 277
  • Mruk DD, et al. Role of tissue inhibitor of metalloproteases-1 in junction dynamics in the testis. J Androl 2003; 24:510 - 523
  • Galdieri M, Ziparo E, Palombi F, Russo MA, Stefanini M. Pure Sertoli cell cultures: a new model for the study of somatic-germ cell interactions. J Androl 1981; 5:249 - 259
  • Li MWM, Mruk DD, Lee WM, Cheng CY. Disruption of the blood-testis barrier integrity by bisphenol A in vitro: Is this a suitable model for studying bloodtestis barrier dynamics?. Int J Biochem Cell Biol 2009; 41:2302 - 2314; http://dx.doi.org/10.1016/j.biocel.2009.05.016
  • Xiao X, Mruk DD, Lee WM, Cheng CY. c-Yes regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization in the seminiferous epithelium of rat testes. Int J Biochem Cell Biol 2011; 43:651 - 665; http://dx.doi.org/10.1016/j.biocel.2011.01.008
  • Lui WY, Cheng CY. Regulation of cell junction dynamics by cytokines in the testis—a molecular and biochemical perspective. Cytokine Growth Factor Rev 2007; 18:299 - 311; http://dx.doi.org/10.1016/j.cytogfr.2007.04.009