Disruption of blood-brain barrier in Alzheimer disease pathogenesis

References

• Nagy Zs, Esiri MM, Joachim C, Jobst KA, Morris JH, King EM, et al. Comparison of pathological diagnostic criteria for Alzheimer disease. Alzheimer Dis Assoc Disord 1998; 12:182 - 9; http://dx.doi.org/10.1097/00002093-199809000-00010; PMID: 9772021
   PubMed Web of Science ®Google Scholar
• Ellis RJ, Olichney JM, Thal LJ, Mirra SS, Morris JC, Beekly D, et al. Cerebral amyloid angiopathy in the brains of patients with Alzheimer’s disease: the CERAD experience, Part XV. Neurology 1996; 46:1592 - 6; http://dx.doi.org/10.1212/WNL.46.6.1592; PMID: 8649554
   PubMed Web of Science ®Google Scholar
• Selkoe DJ. Alzheimer’s disease: genes, proteins, and therapy. Physiol Rev 2001; 81:741 - 66; PMID: 11274343
   PubMed Web of Science ®Google Scholar
• Claudio L. Ultrastructural features of the blood-brain barrier in biopsy tissue from Alzheimer’s disease patients. Acta Neuropathol 1996; 91:6 - 14; http://dx.doi.org/10.1007/s004010050386; PMID: 8773140
   PubMed Web of Science ®Google Scholar
• Heyman A, Fillenbaum GG, Welsh-Bohmer KA, Gearing M, Mirra SS, Mohs RC, et al. Cerebral infarcts in patients with autopsy-proven Alzheimer’s disease: CERAD, part XVIII. Consortium to Establish a Registry for Alzheimer’s Disease. Neurology 1998; 51:159 - 62; http://dx.doi.org/10.1212/WNL.51.1.159; PMID: 9674796
   PubMed Web of Science ®Google Scholar
• Abbott NJ, Rönnbäck L, Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 2006; 7:41 - 53; http://dx.doi.org/10.1038/nrn1824; PMID: 16371949
   PubMed Web of Science ®Google Scholar
• Watson PM, Anderson JM, Vanltallie CM, Doctrow SR. The tight-junction-specific protein ZO-1 is a component of the human and rat blood-brain barriers. Neurosci Lett 1991; 129:6 - 10; http://dx.doi.org/10.1016/0304-3940(91)90708-2; PMID: 1922971
   PubMed Web of Science ®Google Scholar
• Fanning AS, Jameson BJ, Jesaitis LA, Anderson JM. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J Biol Chem 1998; 273:29745 - 53; http://dx.doi.org/10.1074/jbc.273.45.29745; PMID: 9792688
   PubMed Web of Science ®Google Scholar
• Yan SD, Chen X, Fu J, Chen M, Zhu H, Roher A, et al. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer’s disease. Nature 1996; 382:685 - 91; http://dx.doi.org/10.1038/382685a0; PMID: 8751438
   PubMed Web of Science ®Google Scholar
• Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, et al. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Nat Med 2003; 9:907 - 13; http://dx.doi.org/10.1038/nm890; PMID: 12808450
   PubMed Web of Science ®Google Scholar
• Shibata M, Yamada S, Kumar SR, Calero M, Bading J, Frangione B, et al. Clearance of Alzheimer’s amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J Clin Invest 2000; 106:1489 - 99; http://dx.doi.org/10.1172/JCI10498; PMID: 11120756
   PubMed Web of Science ®Google Scholar
• Matsubara E, Ghiso J, Frangione B, Amari M, Tomidokoro Y, Ikeda Y, et al. Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer’s disease and Down’s syndrome. Ann Neurol 1999; 45:537 - 41; http://dx.doi.org/10.1002/1531-8249(199904)45:4<537::AID-ANA20>3.0.CO;2-2; PMID: 10211483
   PubMed Web of Science ®Google Scholar
• Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, Younkin SG. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer’s disease. J Neurosci 2001; 21:372 - 81; PMID: 11160418
   PubMed Web of Science ®Google Scholar
• Kawahara M, Kuroda Y, Arispe N, Rojas E. Alzheimer’s beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line. J Biol Chem 2000; 275:14077 - 83; http://dx.doi.org/10.1074/jbc.275.19.14077; PMID: 10799482
   PubMed Web of Science ®Google Scholar
• Kagan BL, Hirakura Y, Azimov R, Azimova R, Lin MC. The channel hypothesis of Alzheimer’s disease: current status. Peptides 2002; 23:1311 - 5; http://dx.doi.org/10.1016/S0196-9781(02)00067-0; PMID: 12128087
   PubMed Web of Science ®Google Scholar
• Bond M, Fabunmi RP, Baker AH, Newby AC. Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-kappa B. FEBS Lett 1998; 435:29 - 34; http://dx.doi.org/10.1016/S0014-5793(98)01034-5; PMID: 9755853
   PubMed Web of Science ®Google Scholar
• Stuart RO, Sun A, Bush KT, Nigam SK. Dependence of epithelial intercellular junction biogenesis on thapsigargin-sensitive intracellular calcium stores. J Biol Chem 1996; 271:13636 - 41; http://dx.doi.org/10.1074/jbc.271.23.13636; PMID: 8662885
   PubMed Web of Science ®Google Scholar
• Cho HJ, Son SM, Jin SM, Hong HS, Shin DH, Kim SJ, et al. RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer’s disease animal model. FASEB J 2009; 23:2639 - 49; http://dx.doi.org/10.1096/fj.08-126383; PMID: 19332646
   PubMed Web of Science ®Google Scholar
• Miravalle L, Tokuda T, Chiarle R, Giaccone G, Bugiani O, Tagliavini F, et al. Substitutions at codon 22 of Alzheimer’s abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells. J Biol Chem 2000; 275:27110 - 6; PMID: 10821838
   PubMed Web of Science ®Google Scholar
• Folin M, Baiguera S, Tommasini M, Guidolin D, Conconi MT, De Carlo E, et al. Effects of beta-amyloid on rat neuromicrovascular endothelial cells cultured in vitro. Int J Mol Med 2005; 15:929 - 35; PMID: 15870895
   PubMed Web of Science ®Google Scholar
• Restituito S, Khatri L, Ninan I, Mathews PM, Liu X, Weinberg RJ, et al. Synaptic autoregulation by metalloproteases and γ-secretase. J Neurosci 2011; 31:12083 - 93; http://dx.doi.org/10.1523/JNEUROSCI.2513-11.2011; PMID: 21865451
   PubMed Web of Science ®Google Scholar
• Hong HS, Hwang JY, Son SM, Kim YH, Moon M, Inhee MJ. FK506 reduces amyloid plaque burden and induces MMP-9 in AβPP/PS1 double transgenic mice. J Alzheimers Dis 2010; 22:97 - 105; PMID: 20847451
   PubMed Web of Science ®Google Scholar
• Gonzalez-Mariscal L, Contreras RG, Bolívar JJ, Ponce A, Chávez De Ramirez B, Cereijido M. Role of calcium in tight junction formation between epithelial cells. Am J Physiol 1990; 259:C978 - 86; PMID: 2124417
   PubMedGoogle Scholar
• Liu F, Grundke-Iqbal I, Iqbal K, Oda Y, Tomizawa K, Gong CX. Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. J Biol Chem 2005; 280:37755 - 62; http://dx.doi.org/10.1074/jbc.M507475200; PMID: 16150694
   PubMed Web of Science ®Google Scholar
• Agostinho P, Lopes JP, Velez Z, Oliveira CR. Overactivation of calcineurin induced by amyloid-beta and prion proteins. Neurochem Int 2008; 52:1226 - 33; http://dx.doi.org/10.1016/j.neuint.2008.01.005; PMID: 18295934
   PubMed Web of Science ®Google Scholar
• Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel RE. beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 1992; 12:376 - 89; PMID: 1346802
   PubMed Web of Science ®Google Scholar
• Simm A, Casselmann C, Schubert A, Hofmann S, Reimann A, Silber RE. Age associated changes of AGE-receptor expression: RAGE upregulation is associated with human heart dysfunction. Exp Gerontol 2004; 39:407 - 13; http://dx.doi.org/10.1016/j.exger.2003.12.006; PMID: 15036400
   PubMed Web of Science ®Google Scholar
• Li M, Shang DS, Zhao WD, Tian L, Li B, Fang WG, et al. Amyloid beta interaction with receptor for advanced glycation end products up-regulates brain endothelial CCR5 expression and promotes T cells crossing the blood-brain barrier. J Immunol 2009; 182:5778 - 88; http://dx.doi.org/10.4049/jimmunol.0803013; PMID: 19380826
   PubMed Web of Science ®Google Scholar
• Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, et al. Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer’s disease mutations: potential factors in amyloid plaque formation. J Neurosci 2006; 26:10129 - 40; http://dx.doi.org/10.1523/JNEUROSCI.1202-06.2006; PMID: 17021169
   PubMed Web of Science ®Google Scholar
• Garcia-Alloza M, Prada C, Lattarulo C, Fine S, Borrelli LA, Betensky R, et al. Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice. J Neurochem 2009; 109:1636 - 47; http://dx.doi.org/10.1111/j.1471-4159.2009.06096.x; PMID: 19457117
   PubMed Web of Science ®Google Scholar