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Editoryal/Editorial

Neuroimaging can help identify biomarkers of early onset bipolar disorder

, MD
Pages 1-4 | Accepted 14 Feb 2011, Published online: 08 Nov 2016

References

  • Pavuluri MN, Birmaher B, Naylor MW. Pediatric bipolar disorder: a review of the past 10 years. Journal of the American Academy of Child & Adolescent Psychiatry 2005; 44(9): 846–71.
  • Birmaher B, Axelson D. Course and outcome of bipolar spectrum disorder in children and adolescents: A review of the existing literature. Development & Psychopathology 2006; 18(6): 1023–35.
  • Diler RSe. Pediatric Bipolar Disorder: A Global Perspective. New York: Nova Science Publishers, Inc.; 2007.
  • Bolge SC, Thompson T, Bourne E, Nanry K. Characteristics and symptomatology of patients diagnosed with unipolar depression at risk for undiagnosed bipolar disorder: a bipolar survey. CNS Spect 2008; 13(3): 216–24.
  • Egeland JA, Shaw JA, Endicott J, Pauls DL, Allen CR, Hostetter AM, et al. Prospective study of prodromal features for bipolarity in well Amish children.[see comment]. Journal of the American Academy of Child & Adlescent Psychiatry 2003; 42(7): 786–96.
  • Chang K, Adleman N, Wagner C, Barnea-Goraly N, Garrett A. Will neuroimaging ever be used to diagnose pediatric bipolar disorder? Development & Psychopathology 2006; 18(4): 1133–46.
  • Phillips ML. Understanding the neurobiology of emotion perception: implications for psychiatry. British Journal of Psychiatry 2003; 182(3): 190–2.
  • Leibenluft E, Rich BA. Pediatric bipolar disorder. Annual Review of Clinical Psychology 2008; 4: 163–87.
  • Phillips ML, Ladouceur CD, Drevets WC. A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder. Molecular Psychiatry 2008; 13(9): 833–57.
  • Chen HH, Nicoletti MA, Hatch JP, Sassi RB, Axelson D, Brambilla P, et al. Abnormal left superior temporal gyrus volumes in children and adolescents with bipolar disorder: a magnetic resonance imaging study. Neurosci Lett 2004; 363(1): 65–8.
  • Blumberg HP, Kaufman J, Martin A, Whiteman R, Zhang JH, Gore JC, et al. Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder. Arch Gen Psychiatry. 2003; 60(12): 1201–8.
  • Chang K, Karchemskiy A, Barnea-Goraly N, Garrett A, Simeonova DI, Reiss A. Reduced amygdalar gray matter volume in familial pediatric bipolar disorder. J Am Acad Child Adolesc Psychiatry 2005; 44(6): 565–73.
  • Frazier JA, Breeze JL, Makris N, Giuliano AS, Herbert MR, Seidman L, et al. Cortical gray matter differences identified by structural magnetic resonance imaging in pediatric bipolar disorder. Bipolar Disord 2005; 7(6): 555–69.
  • Dickstein DP, Milham MP, Nugent AC, Drevets WC, Charney DS, Pine DS, et al. Frontotemporal alterations in pediatric bipolar disorder: results of a voxel-based morphometry study. Arch Gen Psychiatry 2005; 62(7): 734–41.
  • Blumberg HP, Krystal JH, Bansal R, Martin A, Dziura J, Durkin K, et al. Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study. Biol Psychiatry 2006; 59(7): 611–8
  • Kaur S, Sassi RB, Axelson D, Nicoletti M, Brambilla P, Monkul ES, et al. Cingulate cortex anatomical abnormalities in children and adolescents with bipolar disorder. Am J Psychiatry 2005; 162(9): 1637–43.
  • Altshuler LL, Bartzokis G, Grieder T, Curran J, Mintz J. Amygdala enlargement in bipolar disorder and hippocampal reduction in schizophrenia: an MRI study demonstrating neuroanatomic specificity. Arch Gen Psychiatry 1998; 55(7): 663–4.
  • Brambilla P, Nicoletti MA, Sassi RB, Mallinger AG, Frank E, Kupfer DJ, et al. Magnetic resonance imaging study of corpus callosum abnormalities in patients with bipolar disorder. Biol Psychiatry 2003; 54(11): 1294–7.
  • Savitz J, Drevets WC. Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide. Neurosci Biobehav Rev 2009; 33(5): 699–71.
  • Pfeifer JC, Welge J, Strakowski SM, Adler CM, DelBello MP. Meta-analysis of amygdala volumes in children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry 2008; 47(11): 1289–98.
  • Doty TJ, Payne ME, Steffens DC, Beyer JL, Krishnan KR, LaBar KS. Age-dependent reduction of amygdala volume in bipolar disorder. Psychiatry Res 2008; 163(1): 84–94.
  • Rosso IM, Killgore WD, Cintron CM, Gruber SA, Tohen M, Yurgelun-Todd DA. Reduced amygdala volumes in first-episode bipolar disorder and correlation with cerebral white matter. Biol Psychiatry 2007; 61(6): 743–9.
  • Bruno SD, Barker GJ, Cercignani M, Symms M, Ron MA. A study of bipolar disorder using magnetization transfer imaging and voxel-based morphometry. Brain 2004; 127(Pt11): 2433–40.
  • Drevets WC, Price JL, Simpson JR, Jr., Todd RD, Reich T, Vannier M, et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 1997; 386(6627): 824–7.
  • Lochhead RA, Parsey RV, Oquendo MA, Mann JJ. Regional brain gray matter volume differences in patients with bipolar disorder as assessed by optimized voxel-based morphometry. Biol Psychiatry 2004; 55(12): 1154–62.
  • Sassi RB, Brambilla P, Hatch JP, Nicoletti MA, Mallinger AG, Frank E, et al. Reduced left anterior cingulate volumes in untreated bipolar patients. Biol Psychiatry 2004; 56(7): 467–75.
  • Lyoo IK, Kim MJ, Stoll AL, Demopulos CM, Parow AM, Dager SR, et al. Frontal lobe gray matter density decreases in bipolar I disorder. Biol Psychiatry 2004; 55(6): 648–51.
  • Dickstein DP, Leibenluft E. Emotion regulation in children and adolescents: boundaries between normalcy and bipolar disorder. Dev Psychopathol 2006; 18(4): 1105–31.
  • Robinson JL, Monkul ES, Tordesillas-Gutierrez D, Franklin C, Bearden CE, Fox PT, et al. Fronto-limbic circuitry in euthymic bipolar disorder: Evidence for prefrontal hyperactivation. Psychiatry Res 2008; 164(2): 106–13.
  • Malhi GS, Lagopoulos J, Sachdev PS, Ivanovski B, Shnier R, Ketter T. Is a lack of disgust something to fear? A functional magnetic resonance imaging facial emotion recognition study in euthymic bipolar disorder patients. Bipolar Disord 2007; 9(4): 345–57.
  • Altshuler L, Bookheimer S, Proenza MA, Townsend J, Sabb F, Firestine A, et al. Increased amygdala activation during mania: a functional magnetic resonance imaging study. Am J Psychiatry 2005; 162(2): 1211–3.
  • Lawrence NS, Williams AM, Surguladze S, Giampietro V, Brammer MJ, Andrew C, et al. Subcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression. Biol Psychiatry 2004; 55(6): 578–87.
  • Wessa M, Houenou J, Paillere-Martinot ML, Berthoz S, Artiges E, Leboyer M, et al. Fronto-striatal overactivation in euthymic bipolar patients during an emotional go/nogo task. Am J Psychiatry 2007; 164(4): 638–46.
  • Pavuluri MN, O'Connor MM, Harral E, Sweeney JA. Affective neural circuitry during facial emotion processing in pediatric bipolar disorder. Biol Psychiatry 2007; 62(2): 158–67.
  • Chang K, Adleman NE, Dienes K, Simeonova DI, Menon V, Reiss A. Anomalous prefrontal-subcortical activation in familial pediatric bipolar disorder: a functional magnetic resonance imaging investigation. Arch Gen Psychiatry 2004; 61(8): 781–92.
  • Pavuluri MN, O'Connor MM, Harral EM, Sweeney JA. An fMRI study of the interface between affective and cognitive neural circuitry in pediatric bipolar disorder. Psychiatry Res 2008; 162(3): 244–55.
  • Pavuluri MN, Passarotti AM, Harral EM, Sweeney JA. An fMRI study of the neural correlates of incidental versus directed emotion processing in pediatric bipolar disorder. J Am Acad Child Adolesc Psychiatry 2009; 48(3): 308–19.
  • Blumberg HP, Martin A, Kaufman J, Leung HC, Skudlarski P, Lacadie C, et al. Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI. Am J Psychiatry 2003; 160(7): 1345–7.
  • Diler RS, Phillips ML, Birmaher B, Almeida JR, Ladouceur CD, D. A. Neural Activity to Positive Stimuli May Differentiate Bipolar Disorder From Major Depressive Disorder in Depressed Youth AACAP and CACAP Joint Annual Meeting. Toronto, Canada: AACAP, 2011: 335.
  • McClure EB, Treland JE, Snow J, Schmajuk M, Dickstein DP, Towbin KE, et al. Deficits in social cognition and response flexibility in pediatric bipolar disorder. Am J Psychiatry 2005; 162(9): 1644–51.
  • Rich BA, Vinton DT, Roberson-Nay R, Hommer RE, Berghorst LH, McClure EB, et al. Limbic hyperactivation during processing of neutral facial expressions in children with bipolar disorder. Proc Natl Acad Sci U S A. 2006; 103(23): 8900–5.
  • Brotman MA, Rich BA, Schmajuk M, Reising M, Monk CS, Dickstein DP, et al. Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disorders. Biol Psychiatry 2007; 61(6): 819–21.
  • McClure EB, Pope K, Hoberman AJ, Pine DS, Leibenluft E. Facial expression recognition in adolescents with mood and anxiety disorders. Am J Psychiatry 2003; 160(6): 1172–4.
  • Pavuluri MN, O'Connor MM, Harral EM, Sweeney JA. An fMRI study of the interface between affective and cognitive neural circuitry in pediatric bipolar disorder. Psychiatry Res 2008; 162(3): 244–55.
  • Rich BA, Fromm SJ, Berghorst LH, Dickstein DP, Brotman MA, Pine DS, et al. Neural connectivity in children with bipolar disorder: impairment in the face emotion processing circuit. J Child Psychol Psychiatry 2008; 49(1): 88–96.
  • Leibenluft E, Charney DS, Pine DS. Researching the pathophysiology of pediatric bipolar disorder. Biol Psychiatry 2003; 53(11): 1009–20.
  • Pavuluri MN, Sweeney JA. Integrating functional brain neuroimaging and developmental cognitive neuroscience in child psychiatry research. J Am Acad Child Adolesc Psychiatry 2008; 47(11): 1273–88.
  • Dickstein DP, Gorrostieta C, Ombao H, Goldberg LD, Brazel AC, Gable CJ, et al. Fronto-temporal spontaneous resting state functional connectivity in pediatric bipolar disorder. Biol Psychiatry 2010; 68(9): 839–46.
  • Adleman NE, Kayser R, Dickstein D, Blair RJ, Pine D, Leibenluft E. Neural correlates of reversal learning in severe mood dysregulation and pediatric bipolar disorder. J Am Acad Child Adolesc Psychiatry 2011; 50(11): 1173–85.
  • Brotman MA, Rich BA, Guyer AE, Lunsford JR, Horsey SE, Reising MM, et al. Amygdala activation during emotion processing of neutral faces in children with severe mood dysregulation versus ADHD or bipolar disorder. Am J Psychiatry 2010; 167(1): 61–9.
  • Passarotti AM, Sweeney JA, Pavuluri MN. Neural correlates of response inhibition in pediatric bipolar disorder and attention deficit hyperactivity disorder. Psychiatry Res 2010; 181(1): 36–43.
  • Passarotti AM, Sweeney JA, Pavuluri MN. Emotion processing influences working memory circuits in pediatric bipolar disorder and attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 2010; 49(10): 1064–80.
  • Pavuluri MN, Passarotti AM, Harral EM, Sweeney JA. Enhanced prefrontal function with pharmacotherapy on a response inhibition task in adolescent bipolar disorder. J Clin Psychiatry 2010; 71(11): 1526–34.
  • Insel TR. Translating scientific opportunity into public health impact: a strategic plan for research on mental illness. Arch Gen Psychiatry 2009; 66(2): 128–33.

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