Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 8
Submit an article Journal homepage
683
Views
5
CrossRef citations to date
0
Altmetric
General Xenobiochemistry

An exposure–response analysis based on rifampin suggests CYP3A4 induction is driven by AUC: an in vitro investigation

Cheng ChangSystems Modeling and Simulation Group, Pharmacokinetics, Dynamics & Metabolism – NCE, Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA and Correspondence[email protected]
,
Xin YangEnzymology and Transporter Group, Pharmacokinetics, Dynamics & Metabolism – NCE, Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA
,
Odette A. FahmiEnzymology and Transporter Group, Pharmacokinetics, Dynamics & Metabolism – NCE, Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA
,
Keith A. RiccardiEnzymology and Transporter Group, Pharmacokinetics, Dynamics & Metabolism – NCE, Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA
,
Li DiEnzymology and Transporter Group, Pharmacokinetics, Dynamics & Metabolism – NCE, Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA
&
R. Scott ObachEnzymology and Transporter Group, Pharmacokinetics, Dynamics & Metabolism – NCE, Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, CT 06340, USA
Pages 673-681 | Received 06 Jul 2016, Accepted 07 Aug 2016, Published online: 05 Sep 2016

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.