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Xenobiotica
the fate of foreign compounds in biological systems
Volume 53, 2023 - Issue 6-7
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Animal Pharmacokinetics and Metabolism

Evaluation of the non-linearity of NA808 in liver not reflected in plasma using a rat pharmacokinetic study and PBPK modelling

Mizuki Yamanea Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan;b Translational Research Division, Chugai Pharmaceutical Co., Ltd, Tokyo, JapanView further author information
,
Kazuhisa Ozekib Translational Research Division, Chugai Pharmaceutical Co., Ltd, Tokyo, JapanView further author information
,
Ken Okanoc Clinical Development Division, Chugai Pharmaceutical Co., Ltd, Tokyo, JapanView further author information
,
Toshiyuki Kudoa Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, JapanView further author information
&
Kiyomi Itoa Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, JapanCorrespondence[email protected]
View further author information
Pages 498-506 | Received 17 Aug 2023, Accepted 02 Oct 2023, Published online: 17 Oct 2023

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