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Xenobiotica
the fate of foreign compounds in biological systems
Volume 53, 2023 - Issue 8-9
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Animal Pharmacokinetics and Metabolism

Evobrutinib pathway to its major metabolite M463-2 and insights from a biotransformation and DDI perspective

Holger Scheiblea NCE DMPK Merck Healthcare KGaA, Darmstadt, GermanyCorrespondence[email protected]
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Hanno Schiefersteina NCE DMPK Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Ralf Schmidtb EMD Serono Research & Development Institute, Inc, Billerica, MA, USA, an affiliate of Merck KGaA, Darmstadt, GermanyView further author information
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Klaus Puseckera NCE DMPK Merck Healthcare KGaA, Darmstadt, GermanyView further author information
,
Ulrike Gradhanda NCE DMPK Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Sathej Gopalakrishnanc Quantitative Pharmacology Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Khalid Iqbalc Quantitative Pharmacology Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Jennifer Dongb EMD Serono Research & Development Institute, Inc, Billerica, MA, USA, an affiliate of Merck KGaA, Darmstadt, GermanyView further author information
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Reinaldo Jonesb EMD Serono Research & Development Institute, Inc, Billerica, MA, USA, an affiliate of Merck KGaA, Darmstadt, GermanyView further author information
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Claudia Melid Merck Ltd, Piedmont, Italy, an affiliate of Merck KGaA, Darmstadt, GermanyView further author information
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Jayaprakasam Bolleddulab EMD Serono Research & Development Institute, Inc, Billerica, MA, USA, an affiliate of Merck KGaA, Darmstadt, GermanyView further author information
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Martin Dyroffb EMD Serono Research & Development Institute, Inc, Billerica, MA, USA, an affiliate of Merck KGaA, Darmstadt, GermanyView further author information
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Katrin Georgia NCE DMPK Merck Healthcare KGaA, Darmstadt, GermanyView further author information
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Pages 547-558 | Received 15 Aug 2023, Accepted 14 Oct 2023, Published online: 25 Oct 2023

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