Supplemental material
Original Articles
Transcriptional profiling of the murine intervertebral disc and age-associated changes in the nucleus pulposus
Matthew A. VerasDepartment of Physiology and Pharmacology, Schulich School of Medicine & Dentistry, The Bone and Joint Institute, The University of Western Ontario, London, Canada
https://orcid.org/0000-0002-4504-5187View further author information
https://orcid.org/0000-0002-4504-5187View further author information, , & Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related Research Data
Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies
Source:
Springer Nature
Age-dependent correlation of low-back pain and lumbar disc degeneration
Source:
Springer Nature America, Inc
Association between promoter -1607 polymorphism of MMP1 and Lumbar Disc Disease in Southern Chinese
Source:
Springer Nature
Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development
Source:
The Company of Biologists
Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus
Source:
Springer Nature
Structure and function of desmosomal proteins and their role in development and disease
Source:
Springer Nature
Expression of Laminin Isoforms, Receptors, and Binding Proteins Unique to Nucleus Pulposus Cells of Immature Intervertebral Disc
Source:
Informa UK Limited
Integrin expression in cells of the intervertebral disc
Source:
Wiley-Blackwell
Lubricin Distribution in the Human Intervertebral Disc
Source:
Ovid Technologies (Wolters Kluwer Health)
Notochordal Cell Produce and Assemble Extracellular Matrix in a Distinct Manner, Which May Be Responsible for the Maintenance of Healthy Nucleus Pulposus
Source:
Ovid Technologies (Wolters Kluwer Health)
Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs
Source:
Springer Nature America, Inc
Are animal models useful for studying human disc disorders/degeneration?
Source:
Springer Science and Business Media LLC
Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.
Source:
Public Library of Science (PLoS)
Expression of Laminin Isoforms, Receptors, and Binding Proteins Unique to Nucleus Pulposus Cells of Immature Intervertebral Disc
Source:
Informa UK Limited
Circulating miRNAs and miRNA shuttles as biomarkers: Perspective trajectories of healthy and unhealthy aging
Source:
Elsevier BV
Mechanical low back pain—a rheumatologist's view
Source:
Springer Nature
A Membranome-Centered Approach Defines Novel Biomarkers for Cellular Subtypes in the Intervertebral Disc
Source:
SAGE Publications
Epidemiological features of chronic low-back pain
Source:
Elsevier BV
Early onset of disc degeneration in SM/J mice is associated with changes in ion transport systems and fibrotic events
Source:
Elsevier BV
Quantitative Proteomic Analysis of Eight Cartilaginous Tissues Reveals Characteristic Differences as well as Similarities between Subgroups
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Aging and Degeneration of the Human Intervertebral Disc
Source:
Ovid Technologies (Wolters Kluwer Health)
A novel mouse model of intervertebral disc degeneration shows altered cell fate and matrix homeostasis
Source:
Elsevier BV
Extracellular Matrix and Adhesion Molecule Gene Expression in the Normal and Injured Murine Intervertebral Disc
Source:
Ovid Technologies (Wolters Kluwer Health)
Identification of cell surface-specific markers to target human nucleus pulposus cells: Expression of carbonic anhydrase XII varies with age and degeneration
Source:
Wiley-Blackwell
A phenotypic comparison of intervertebral disc and articular cartilage cells in the rat
Source:
Springer Nature
Structure and function of the notochord: an essential organ for chordate development
Source:
The Company of Biologists
Transcriptional profiling distinguishes inner and outer annulus fibrosus from nucleus pulposus in the bovine intervertebral disc
Source:
Springer Nature
DEFINING THE PHENOTYPE OF YOUNG HEALTHY NUCLEUS
Source:
Wiley
Whole-body vibration of mice induces progressive degeneration of intervertebral discs associated with increased expression of Il-1β and multiple matrix degrading enzymes
Source:
Elsevier BV
Repeated Exposure to High-Frequency Low-Amplitude Vibration Induces Degeneration of Murine Intervertebral Discs and Knee Joints
Source:
Wiley-Blackwell
Differential Phenotype of Intervertebral Disc Cells
Source:
Ovid Technologies (Wolters Kluwer Health)
Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways
Source:
Informa UK Limited
Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration
Source:
Springer Nature
Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration
Source:
Springer Nature
Wnt Signaling Activates Shh Signaling in Early Postnatal Intervertebral Discs, and Re-Activates Shh Signaling in Old Discs in the Mouse
Source:
Public Library of Science (PLoS)
Serpina3n accelerates tissue repair in a diabetic mouse model of delayed wound healing
Source:
Springer Nature
Genome-Wide Analysis of Pain-, Nerve- and Neurotrophin -Related Gene Expression in the Degenerating Human Annulus
Source:
SAGE Publications
Role of creatine kinase in cardiac excitation-contraction coupling: studies in creatine kinase-deficient mice
Source:
FASEB
Loss of notochord-derived CCN2 results in impaired intervertebral disc development and premature disc degeneration
Source:
Wiley-Blackwell
Age-Related Increases of Macroautophagy and Chaperone-Mediated Autophagy in Rat Nucleus Pulposus
Source:
Informa UK Limited
Loss of ENT1 increases cell proliferation in the annulus fibrosus of the intervertebral disc
Source:
Wiley
Intervertebral disc development and disease-related genetic polymorphisms
Source:
Elsevier BV
Quality Assessment of Surgical Disc Samples Discriminates Human Annulus Fibrosus and Nucleus Pulposus on Tissue and Molecular Level
Source:
MDPI AG
Transcriptional profiling of the murine intervertebral disc and age-associated changes in the nucleus pulposus
Source:
Taylor & Francis
Lumbar Degenerative Disc Disease: Current and Future Concepts of Diagnosis and Management
Source:
Hindawi Limited
Degeneration of the intervertebral disc
Source:
Springer Science and Business Media LLC
Summaries of Affymetrix GeneChip probe level data
Source:
Oxford University Press (OUP)
Preliminary Evaluation of a Scheme for Grading the Gross Morphology of the Human Intervertebral Disc
Source:
Ovid Technologies (Wolters Kluwer Health)
Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
Source:
Springer Science and Business Media LLC
Functional integrin subunits regulating cell–matrix interactions in the intervertebral disc
Source:
Wiley
Modulation of Functional Properties of Galectin-3 by Monoclonal Antibodies Binding to the Non-Lectin Domains†
Source:
American Chemical Society (ACS)
Acute Vibration Induces Transient Expression of Anabolic Genes in the Murine Intervertebral Disc
Source:
Wiley-Blackwell
Autophagy in the Degenerating Human Intervertebral Disc
Source:
Ovid Technologies (Wolters Kluwer Health)
Lumbar Disc Degeneration
Source:
Ovid Technologies (Wolters Kluwer Health)
Impaired Annulus Fibrosis Development and Vertebral Fusion Cause Severe Scoliosis in Mice with Deficiency of c-Jun NH2-Terminal Kinases 1 and 2
Source:
Elsevier BV
Transcriptional profiling of the murine intervertebral disc and age-associated changes in the nucleus pulposus
Source:
Taylor & Francis
Microarray Analysis of Laser Capture Microdissected-Anulus Cells From the Human Intervertebral Disc
Source:
Ovid Technologies (Wolters Kluwer Health)
Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration
Source:
Springer Nature
Molecular profiling of chordoma
Source:
Spandidos Publications
Passive cigarette smoking changes the circadian rhythm of clock genes in rat intervertebral discs
Source:
Wiley-Blackwell
Lumbar Disc Degeneration
Source:
Ovid Technologies (Wolters Kluwer Health)
Potential biomarkers of the mature intervertebral disc identified at the single cell level.
Source:
Wiley
What is intervertebral disc degeneration, and what causes it?
Source:
Ovid Technologies (Wolters Kluwer Health)
Identification of novel nucleus pulposus markers
Source:
British Editorial Society of Bone & Joint Surgery
Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes
Source:
Springer Nature
Lumbar Disc Degeneration
Source:
Ovid Technologies (Wolters Kluwer Health)
Linking provided by
