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Original Research
A randomized, double-blind, single-dose, phase 1 study comparing the pharmacokinetics, pharmacodynamics, safety, and immunogenicity of denosumab biosimilar CT‑P41 and reference denosumab in healthy males
Anhye Kima Department of Clinical Pharmacology and Therapeutics, CHA University School of Medicine, Seongnam, Republic of Korea
https://orcid.org/0000-0002-6622-8089View further author information
Jang Hee Hongb Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, Republic of Korea
https://orcid.org/0000-0002-0623-5455View further author information
Wonsuk Shina Department of Clinical Pharmacology and Therapeutics, CHA University School of Medicine, Seongnam, Republic of Korea
https://orcid.org/0000-0002-6163-5726View further author information
Hyounggyoon Yooa Department of Clinical Pharmacology and Therapeutics, CHA University School of Medicine, Seongnam, Republic of Korea
https://orcid.org/0000-0003-2785-4383View further author information
Jin-Gyu Jungb Department of Pharmacology, College of Medicine, Chungnam National University, Daejeon, Republic of Korea
https://orcid.org/0000-0002-2591-4867View further author information
Jean-Yves Reginsterc WHO Collaborating Center for Epidemiology of Musculoskeletal Health and Aging, Liège, Belgium;d College of Science, Kind Saud University, Riyadh, Kingdom of Saudi Arabia
https://orcid.org/0000-0001-6290-752XView further author information
SungHyun Kime Celltrion, Inc., Incheon, Republic of KoreaView further author information
, YunJu Baee Celltrion, Inc., Incheon, Republic of KoreaView further author information
, JeeHye Suhe Celltrion, Inc., Incheon, Republic of KoreaView further author information
, Sera Kime Celltrion, Inc., Incheon, Republic of KoreaView further author information
, EunKyung Leee Celltrion, Inc., Incheon, Republic of KoreaView further author information
& Stuart Silvermanf Department of Medicine, Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, USA;g OMC Clinical Research Center, Beverly Hills, CA, USACorrespondence[email protected]
https://orcid.org/0000-0002-5313-1018View further author information
Pages 655-663
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Received 20 Dec 2023, Accepted 06 Feb 2024, Published online: 22 Feb 2024
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