Supplemental material
Expert Review of Anticancer Therapy
Volume 19, 2019 - Issue 7
Related Research Data
Expression profile of SIX family members correlates with clinic-pathological features and prognosis of breast cancer
Source:
Ovid Technologies (Wolters Kluwer Health)
The microbiome and cancer
Source:
Wiley
Combined Androgen receptor blockade overcomes the resistance of breast cancer cells to palbociclib
Source:
Ivyspring International Publisher
Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response
Source:
American Association for Cancer Research (AACR)
Isolation of genes by complementation in yeast: molecular cloning of a cell-cycle gene.
Source:
Proceedings of the National Academy of Sciences
Cyclin D1 Represses Gluconeogenesis via Inhibition of the Transcriptional Coactivator PGC1
Source:
American Diabetes Association
Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle
Source:
Elsevier BV
Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: Implications for breast cancer and DCIS therapy with autophagy inhibitors
Source:
Informa UK Limited
Identification of G1 kinase activity for cdk6, a novel cyclin D partner.
Source:
American Society for Microbiology
The microbiome and cancer
Source:
Wiley
Recent advances with cyclin-dependent kinase inhibitors: therapeutic agents for breast cancer and their role in immuno-oncology
Source:
Figshare
microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling
Source:
Proceedings of the National Academy of Sciences
D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA.
Source:
Cell
Targeting the RB-E2F pathway in breast cancer
Source:
Springer Nature
CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
Source:
American Association for Cancer Research (AACR)
Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase
Source:
Elsevier BV
Cell cycle kinases as therapeutic targets for cancer
Source:
Springer Nature
Activation of thecyclin D1Gene by the E1A-associated Protein p300 through AP-1 Inhibits Cellular Apoptosis
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Cyclin D1 Promotes Androgen-Dependent DNA Damage Repair in Prostate Cancer Cells
Source:
American Association for Cancer Research (AACR)
The Kinase-Independent, Second Life of CDK6 in Transcription
Source:
Elsevier BV
Cancer statistics, 2017
Source:
Wiley
Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
Source:
Elsevier BV
Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway
Source:
Massachusetts Medical Society
Cancer stem cells
Source:
Elsevier BV
Genetic control of the cell division cycle in yeast: II. Genes controlling DNA replication and its initiation☆☆☆
Source:
Elsevier BV
Palbociclib in Hormone-Receptor–Positive Advanced Breast Cancer
Source:
New England Journal of Medicine (NEJM/MMS)
A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and Lymphomas
Source:
American Association for Cancer Research (AACR)
ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice
Source:
American Society for Clinical Investigation
Phosphorylation of Cyclin D1 Regulated by ATM or ATR Controls Cell Cycle Progression
Source:
American Society for Microbiology
PD-L1 Expression in Triple-Negative Breast Cancer
Source:
American Association for Cancer Research (AACR)
The microbiome and cancer
Source:
Wiley
Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity
Source:
American Association for the Advancement of Science (AAAS)
Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts.
Source:
Cold Spring Harbor Laboratory
Palbociclib in Hormone-Receptor–Positive Advanced Breast Cancer
Source:
New England Journal of Medicine (NEJM/MMS)
Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer
Source:
American Association for Cancer Research (AACR)
Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome
Source:
Ivyspring International Publisher
Cell cycle kinases in cancer
Source:
Elsevier BV
Mammary Hyperplasia and Carcinoma in MMTV-cyclin D1 Transgenic Mice
Source:
Springer Science and Business Media LLC
Hallmarks of cancer: the next generation.
Source:
Elsevier Inc.
A Novel Mechanism by Which Thiazolidinediones Facilitate the Proteasomal Degradation of Cyclin D1 in Cancer Cells
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Phase II trial of utidelone as monotherapy or in combination with capecitabine in heavily pretreated metastatic breast cancer patients
Source:
Springer Nature
Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma
Source:
American Association for Cancer Research (AACR)
Cyclin D1 in Breast Cancer Pathogenesis
Source:
American Society of Clinical Oncology (ASCO)
Phase III Randomized Study of Ribociclib and Fulvestrant in Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: MONALEESA-3
Source:
American Society of Clinical Oncology (ASCO)
Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system.
Source:
American Society for Microbiology
DNA damage-dependent cyclin D1 proteolysis: GSK3β holds the smoking gun
Source:
Informa UK Limited
Hallmarks of cancer: the next generation.
Source:
Elsevier Inc.
Cancer stem cell metabolism
Source:
BioMed Central
Chimeric antigen receptor T cells: a novel therapy for solid tumors
Source:
Springer Nature
A Topoisomerase II -Mediated dsDNA Break Required for Regulated Transcription
Source:
American Association for the Advancement of Science (AAAS)
MONARCH 2: Abemaciclib in Combination With Fulvestrant in Women With HR+/HER2- Advanced Breast Cancer Who Had Progressed While Receiving Endocrine Therapy.
Source:
American Society of Clinical Oncology (ASCO)
Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors.
Source:
Informa UK Limited
The Putative Oncogene PRAD1 Encodes a Novel Cyclin
Source:
Cold Spring Harbor Laboratory
CDK6 Antagonizes p53-Induced Responses during Tumorigenesis
Source:
American Association for Cancer Research (AACR)
Gene Expression and Cell Cycle Arrest Mediated by Transcription Factor DMP1 Is Antagonized by D-Type Cyclins through a Cyclin-Dependent-Kinase-Independent Mechanism
Source:
American Society for Microbiology
Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells
Source:
Springer Nature
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
Source:
Cold Spring Harbor Laboratory
Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors
Source:
American Association for Cancer Research (AACR)
Cyclin D1 and D3 associate with the SCF complex and are coordinately elevated in breast cancer
Source:
Springer Nature
Cancer Cell Cycles
Source:
American Association for the Advancement of Science (AAAS)
Kinase independent oncogenic cyclin D1
Source:
Impact Journals, LLC
Molecular cloning and chromosomal mapping of DNA rearranged with the parathyroid hormone gene in a parathyroid adenoma.
Source:
American Society for Clinical Investigation
A Journey in Science: Cell-Cycle Control
Source:
Springer Nature
CDK4/6 inhibition triggers anti-tumour immunity
Source:
Springer Science and Business Media LLC
Cyclin-dependent kinases
Source:
Springer Nature
Cyclin D1 is a nuclear protein required for cell cycle progression in G1.
Source:
Cold Spring Harbor Laboratory
D-Cyclins Repress Apoptosis in Hematopoietic Cells by Controlling Death Receptor Fas and Its Ligand FasL
Source:
Elsevier BV
Estrogen Signaling and the DNA Damage Response in Hormone Dependent Breast Cancers
Source:
Frontiers Media SA
Genetic control of cell size at cell division in yeast
Source:
Springer Nature
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
Source:
Proceedings of the National Academy of Sciences
Forging a signature of in vivo senescence
Source:
Springer Nature
Transcriptional Regulation by a DNA-associated Form of Cyclin D1
Source:
American Society for Cell Biology (ASCB)
Targeting Cyclins and Cyclin-Dependent Kinases in Cancer: Lessons from Mice, Hopes for Therapeutic Applications in Humans
Source:
Informa UK Limited
A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation
Source:
Rockefeller University Press
Recent advances of highly selective CDK4/6 inhibitors in breast cancer
Source:
Springer Science and Business Media LLC
Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo
Source:
Cold Spring Harbor Laboratory
Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint
Source:
American Association for Cancer Research (AACR)
A long non-coding RNA point of view
Source:
Informa UK Limited
Analysis of the Human Endogenous Coregulator Complexome
Source:
Elsevier BV
CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion
Source:
American Association for Cancer Research (AACR)
The history and future of targeting cyclin-dependent kinases in cancer therapy
Source:
Springer Science and Business Media LLC
Cyclin D1 Antagonizes BRCA1 Repression of Estrogen Receptor α Activity
Source:
American Association for Cancer Research (AACR)
Specific protection against breast cancers by cyclin D1 ablation
Source:
Springer Science and Business Media LLC
A splice variant of Skp2 is retained in the cytoplasm and fails to direct cyclin D1 ubiquitination in the uterine cancer cell line SK-UT
Source:
Springer Nature
Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration–proliferation dichotomy
Source:
Proceedings of the National Academy of Sciences
A long non-coding RNA point of view
Source:
Informa UK Limited
CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib
Source:
EMBO
Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy
Source:
Informa UK Limited
Thyroid hormones and the cardiovascular system: Pathophysiology and interventions
Source:
Elsevier BV
Stromal fibroblasts in cancer initiation and progression
Source:
Springer Nature
PRMT5 Is Required for Lymphomagenesis Triggered by Multiple Oncogenic Drivers
Source:
American Association for Cancer Research (AACR)
A Critical Role for FBXW8 and MAPK in Cyclin D1 Degradation and Cancer Cell Proliferation
Source:
Public Library of Science (PLoS)
Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs
Source:
Springer Nature
Aberrant Expression of Cyclin D1 in Cancer
Source:
SAGE Publications
Effects of miRNAs on functions of breast cancer stem cells and treatment of breast cancer
Source:
Dove Medical Press Ltd.
Fission yeast cyclin: subcellular localisation and cell cycle regulation
Source:
The Company of Biologists
Small Non-coding RNAs Govern Mammary Gland Tumorigenesis
Source:
Springer Nature
Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe
Source:
Elsevier BV
Biological functions of CDK5 and potential CDK5 targeted clinical treatments
Source:
Impact Journals, LLC
Targeting Cancer Stem Cell Redox Metabolism to Enhance Therapy Responses
Source:
Elsevier BV
Distinct initiation and maintenance mechanisms cooperate to induce G1 cell cycle arrest in response to DNA damage.
Source:
Elsevier BV
Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4
Source:
Cold Spring Harbor Laboratory
The Genetic Landscape and Clonal Evolution of Breast Cancer Resistance to Palbociclib plus Fulvestrant in the PALOMA-3 Trial
Source:
American Association for Cancer Research (AACR)
Transcriptional role of cyclin D1 in development revealed by a genetic–proteomic screen
Source:
Springer Nature
p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
Source:
Springer Nature
Recent advances with cyclin-dependent kinase inhibitors: therapeutic agents for breast cancer and their role in immuno-oncology
Source:
Figshare
Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in ApcMin Mice
Source:
American Society for Microbiology
D-Type Cyclins and Gene Transcription
Source:
Springer International Publishing
Comprehensive molecular portraits of human breast tumours
Source:
Springer Science and Business Media LLC
Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins
Source:
Elsevier BV
Cyclin D1 Inhibits Peroxisome Proliferator-activated Receptor γ-mediated Adipogenesis through Histone Deacetylase Recruitment
Source:
Elsevier BV
A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma
Source:
Elsevier BV
Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance
Source:
Springer Science and Business Media LLC
Breast Cancer and Its Relationship with the Microbiota
Source:
MDPI AG
Cyclin D1 Determines Mitochondrial Function InVivo
Source:
American Society for Microbiology
Cell cycle, CDKs and cancer: a changing paradigm
Source:
Springer Science and Business Media LLC
The retinoblastoma protein and cell cycle control
Source:
Elsevier BV
Insights into Pathogenic Interactions Among Environment, Host, and Tumor at the Crossroads of Molecular Pathology and Epidemiology
Source:
Annual Reviews
Molecular pathological epidemiology: new developing frontiers of big data science to study etiologies and pathogenesis
Source:
Springer Science and Business Media LLC
Osmotic Stress Regulates the Stability of Cyclin D1 in a p38SAPK2-dependent Manner
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer
Source:
American Association for Cancer Research (AACR)
New roles of cyclin D1.
Source:
American Society for Investigative Pathology. Published by Elsevier Inc.
The Role of Cdk5 in Neuroendocrine Thyroid Cancer
Source:
Elsevier BV
Cyclin D1 Integrates Estrogen-Mediated DNA Damage Repair Signaling
Source:
American Association for Cancer Research (AACR)
The fission yeast cdc2/cdc13/suc1 protein kinase: Regulation of catalytic activity and nuclear localization
Source:
Elsevier BV
Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor–Positive Breast Cancer
Source:
American Association for Cancer Research (AACR)
Initiation of stem cell differentiation involves cell cycle-dependent regulation of developmental genes by Cyclin D
Source:
Cold Spring Harbor Laboratory
Inflammatory breast cancer: a new approach
Source:
Elsevier BV
Minireview: Cyclin D1: Normal and Abnormal Functions
Source:
The Endocrine Society
A brain-specific activator of cyclin-dependent kinase 5
Source:
Springer Nature
A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers
Source:
Springer Science and Business Media LLC
E2F and Cell Proliferation: A World Turned Upside Down
Source:
Elsevier BV
Human D-type cyclin
Source:
Elsevier BV
Overall Survival with Palbociclib and Fulvestrant in Advanced Breast Cancer
Source:
New England Journal of Medicine (NEJM/MMS)
Cyclin D1 Repression of Peroxisome Proliferator-Activated Receptor Expression and Transactivation
Source:
American Society for Microbiology
Overview of cyclins D1 function in cancer and the CDK inhibitor landscape: past and present
Source:
Informa Healthcare
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells.
Source:
Springer Science and Business Media LLC
Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression
Source:
Springer Science and Business Media LLC
Linking provided by
