Supplemental material
Open access
2,053
Views
27
CrossRef citations to date
0
Altmetric
Research Paper
Synthesis, biological activity and multiscale molecular modeling studies for coumaryl-carboxamide derivatives as selective carbonic anhydrase IX inhibitors
Belma Zengin KurtFaculty of Pharmacy, Department of Pharmaceutical Chemistry, Bezmialem Vakıf University, Istanbul, Turkey; View further author information
, Fatih SonmezFaculty of Arts and Science, Department of Chemistry, Sakarya University, Sakarya, Turkey; Correspondence[email protected]
View further author information
, View further author information
Serdar DurdagiComputational Biology and Molecular Simulations Laboratory, Department of Biophysics, School of Medicine, Bahcesehir University, Istanbul, Turkey; Correspondence[email protected]
View further author information
, View further author information
Busecan AksoydanComputational Biology and Molecular Simulations Laboratory, Department of Biophysics, School of Medicine, Bahcesehir University, Istanbul, Turkey; View further author information
, Ramin Ekhteiari SalmasComputational Biology and Molecular Simulations Laboratory, Department of Biophysics, School of Medicine, Bahcesehir University, Istanbul, Turkey; View further author information
, Andrea AngeliDipartimento Neurofarba, Sezione di ScienzeFarmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Florence, ItalyView further author information
, Mustafa KucukislamogluFaculty of Arts and Science, Department of Chemistry, Sakarya University, Sakarya, Turkey; View further author information
& Claudiu T. SupuranDipartimento Neurofarba, Sezione di ScienzeFarmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Florence, ItalyView further author information
show all
Pages 1042-1052
|
Received 22 May 2017, Accepted 10 Jul 2017, Published online: 04 Aug 2017
Related Research Data
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.
Source:
American Chemical Society (ACS)
Synthesis of Some Novel Norbornene-Fused Pyridazines
Source:
Wiley
Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.
Source:
HAL CCSD
Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII
Source:
Elsevier BV
Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: Novel sulfamoylcarbamates and sulfamides derived from acetophenones
Source:
Elsevier BV
Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
Source:
Springer Science and Business Media LLC
Activation studies of the α- and β-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae with amines and amino acids.
Source:
Informa UK Limited
Carbonic anhydrase inhibitors and activators for novel therapeutic applications
Source:
Future Science Ltd
Carbonic anhydrase inhibitors: Design, synthesis, kinetic, docking and molecular dynamics analysis of novel glycine and phenylalanine sulfonamide derivatives.
Source:
PERGAMON-ELSEVIER SCIENCE LTD
Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX
Source:
Informa UK Limited
6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.
Source:
American Chemical Society (ACS)
Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis
Source:
American Chemical Society (ACS)
Improved protein-ligand docking using GOLD.
Source:
Wiley
Synthesis and anticholinesterase activity of coumarin-3-carboxamides bearing tryptamine moiety
Source:
Elsevier BV
Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs.
Source:
American Chemical Society (ACS)
Dendrimers incorporating benzenesulfonamide moieties strongly inhibit carbonic anhydrase isoforms I-XIV.
Source:
Royal Society of Chemistry (RSC)
Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series.
Source:
American Chemical Society (ACS)
Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Source:
American Chemical Society (ACS)
Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors
Source:
American Chemical Society (ACS)
In silico investigation of PARP-1 catalytic domains in holo and apo states for the design of high-affinity PARP-1 inhibitors
Source:
Taylor & Francis
A class of 4-sulfamoylphenyl-ω-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects.
Source:
American Chemical Society (ACS)
Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins
Source:
American Chemical Society (ACS)
Current developments in chemistry, coordination, structure and biological aspects of 1-(acyl/aroyl)-3- (substituted)thioureas: advances Continue …
Source:
Informa UK Limited
Modulation of carbonic anhydrase 9 (CA9) in human brain cancer.
Source:
Bentham Science Publishers Ltd.
New aminobenzenesulfonamide-thiourea conjugates: synthesis and carbonic anhydrase inhibition and docking studies.
Source:
Elsevier BV
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.