Supplemental material
Journal of Enzyme Inhibition and Medicinal Chemistry
Volume 33, 2018 - Issue 1
Related Research Data
Principles and applications of halogen bonding in medicinal chemistry and chemical biology.
Source:
American Chemical Society (ACS)
GPI-specific phospholipase D mRNA expression in tumor cells of different malignancy.
Source:
Springer Science and Business Media LLC
Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1,2,3-triazole-coumarin hybrids.
Source:
Elsevier BV
Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer.
Source:
Elsevier BV
The binding database: Overview and user's guide
Source:
Wiley
A phase I study of binimetinib (MEK162) in Japanese patients with advanced solid tumors
Source:
Springer Science and Business Media LLC
Prediction of Absolute Solvation Free Energies using Molecular Dynamics Free Energy Perturbation and the OPLS Force Field.
Source:
American Chemical Society (ACS)
Signal integration by JNK and p38 MAPK pathways in cancer development
Source:
Springer Science and Business Media LLC
MAP kinases and cell migration
Source:
The Company of Biologists
Chapter 6:Probabilistic Approaches in Activity Prediction
Source:
Royal Society of Chemistry
Nucleosides and oligonucleotides containing 1,2,3-triazole residues with nucleobase tethers: synthesis via the azide-alkyne 'click' reaction.
Source:
Elsevier BV
A First-in-Human Phase I Study of the Oral p38 MAPK Inhibitor, Ralimetinib (LY2228820 Dimesylate), in Patients with Advanced Cancer
Source:
American Association for Cancer Research (AACR)
Halogen bonding--a novel interaction for rational drug design?
Source:
American Chemical Society (ACS)
1,2,3-Triazole pharmacophore-based benzofused nitrogen/sulfur heterocycles with potential anti-Moraxella catarrhalis activity.
Source:
Elsevier BV
MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study
Source:
Elsevier
Silver(I)-mediated oxidative C(sp3)–H amination of ethers with azole derivatives under mild conditions
Source:
Royal Society of Chemistry (RSC)
A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor.
Source:
Springer Science and Business Media LLC
A Phase I Study of Oral ARRY-614, a p38 MAPK/Tie2 Dual Inhibitor, in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes
Source:
American Association for Cancer Research (AACR)
MAP kinase signalling pathways in cancer.
Source:
Springer Science and Business Media LLC
NF-κB is a target of AKT in anti-apoptotic PDGF signalling
Source:
Springer Science and Business Media LLC
p38 MAPK in development and cancer.
Source:
Informa UK Limited
Halogen bonds in biological molecules
Source:
HAL CCSD
Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids
Source:
American Chemical Society (ACS)
Extra Precision Glide: Docking and Scoring Incorporating a Model of Hydrophobic Enclosure for Protein-Ligand Complexes
Source:
American Chemical Society (ACS)
The VSGB 2.0 Energy Model
Source:
Wiley
Linking provided by
