Supplemental material
Journal of Enzyme Inhibition and Medicinal Chemistry
Volume 33, 2018 - Issue 1
Short Communication
Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors
, , 
, , , , , , & show all
Carlotta GranchiDepartment of Pharmacy, University of Pisa, Pisa, Italy; http://orcid.org/0000-0002-5849-0722View further author information
http://orcid.org/0000-0002-5849-0722View further author information, , , , Flavio RizzolioPathology Unit, Department of Molecular Biology and Translational Research, National Cancer Institute and Center for Molecular Biomedicine, Aviano (PN), Italy; ;Department of Molecular Science and Nanosystems, Ca' Foscari Università di Venezia, Venezia-Mestre, Italy; http://orcid.org/0000-0002-3400-4363View further author information
http://orcid.org/0000-0002-3400-4363View further author information, , Filippo MinutoloDepartment of Pharmacy, University of Pisa, Pisa, Italy; http://orcid.org/0000-0002-3312-104XView further author information
http://orcid.org/0000-0002-3312-104XView further author information & Tiziano TuccinardiDepartment of Pharmacy, University of Pisa, Pisa, Italy; ;Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA, USACorrespondence[email protected]
http://orcid.org/0000-0002-6205-4069View further author information
http://orcid.org/0000-0002-6205-4069View further author information show allRelated Research Data
Dopamine Regulation of Fyn and mGluR5
Source:
Wiley
Improved protein-ligand docking using GOLD.
Source:
Wiley
Calculating Structures and Free Energies of Complex Molecules: Combining Molecular Mechanics and Continuum Models
Source:
American Chemical Society (ACS)
Structure of human Fyn kinase domain complexed with staurosporine.
Source:
Elsevier BV
The effect of long‐range electrostatic interactions in simulations of macromolecular crystals: A comparison of the Ewald and truncated list methods
Source:
AIP Publishing
Morphological Differentiation of Oligodendrocytes Requires Activation of Fyn Tyrosine Kinase
Source:
Rockefeller University Press
Identification of New Fyn Kinase Inhibitors Using a FLAP-Based Approach
Source:
American Chemical Society (ACS)
Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor STUDY OF Lck- AND FynT-DEPENDENT T CELL ACTIVATION
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Extensive Reliability Evaluation of Docking-Based Target-Fishing Strategies.
Source:
Multidisciplinary Digital Publishing Institute
Conformer Generation with OMEGA: Algorithm and Validation Using High Quality Structures from the Protein Databank and Cambridge Structural Database
Source:
American Chemical Society (ACS)
Neuroblastoma tyrosine kinase signaling networks involve FYN and LYN in endosomes and lipid rafts.
Source:
Public Library of Science (PLoS)
Fyn kinase in brain diseases and cancer: the search for inhibitors.
Source:
Bentham Science Publishers Ltd.
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation.
Source:
Universit��t Ulm
Receptor-based virtual screening evaluation for the identification of estrogen receptor β ligands.
Source:
Informa UK Limited
Application of a FLAP-Consensus Docking Mixed Strategy for the Identification of New Fatty Acid Amide Hydrolase Inhibitors
Source:
American Chemical Society (ACS)
LPA Induces Ovarian Cancer Cell Dispersal
Source:
Wiley
Extensive consensus docking evaluation for ligand pose prediction and virtual screening studies.
Source:
American Chemical Society (ACS)
MOBP levels are regulated by Fyn kinase and affect the morphological differentiation of oligodendrocytes.
Source:
The Company of Biologists
Synthesis, Modeling, and RET Protein Kinase Inhibitory Activity of 3-and 4-Substituted beta-Carbolin-1-ones
Source:
American Chemical Society (ACS)
A novel molecular target in cancer
Source:
Wiley
Differential matrix rigidity response in breast cancer cell lines correlates with the tissue tropism.
Source:
Public Library of Science (PLoS)
Fyn Activation Regulates BDNF-Induced Myelination
Source:
Wiley
Phosphorylation of Tau by Fyn: Implications for Alzheimer's Disease
Source:
Society for Neuroscience
In-vivo crystals reveal protein interactions
Source:
bioRxiv
FYN is overexpressed in human prostate cancer.
Source:
Wiley
A signature predictive of disease outcome in breast carcinomas, identified by quantitative immunocytochemical assays.
Source:
Wiley
Oxime-based inhibitors of glucose transporter 1 displaying antiproliferative effects in cancer cells
Source:
Elsevier BV
Fyn is an important molecule in cancer pathogenesis and drug resistance.
Source:
Elsevier BV
pharmACOphore: multiple flexible ligand alignment based on ant colony optimization.
Source:
Springer Nature
Inhibition of carbonic anhydrase isoforms I, II, IX and XII with secondary sulfonamides incorporating benzothiazole scaffolds.
Source:
Informa UK Limited
Linking provided by
