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Research Paper
Synthesis, antitumour activities and molecular docking of thiocarboxylic acid ester-based NSAID scaffolds: COX-2 inhibition and mechanistic studies
Adel S. El-AzabDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; ;Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt; Correspondence[email protected] [email protected]
http://orcid.org/0000-0001-7197-1515
, http://orcid.org/0000-0001-7197-1515
Alaa A.-M. Abdel-AzizDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; ;Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt; http://orcid.org/0000-0002-3362-9337
, Laila A. Abou-ZeidDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt;
, Walaa M. El-HusseinyDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt;
, Ahmad M. El_MorsyDepartment of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt;
, Manal A. El-GendyDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;
& Magda A.-A. El-SayedDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt; ;Department of Pharmaceutical Chemistry, Faculty of pharmacy, Horus university, New Damietta, Egypthttp://orcid.org/0000-0001-9599-9248
show all
Pages 989-998
|
Received 26 Mar 2018, Accepted 07 May 2018, Published online: 28 May 2018
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