Supplemental material
Journal of Enzyme Inhibition and Medicinal Chemistry
Volume 34, 2019 - Issue 1
Related Research Data
Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally
Source:
American Society for Microbiology
Histone acetylation in chromatin structure and transcription
Source:
Springer Science and Business Media LLC
Synthesis and Activity of New Aryl- and Heteroaryl-Substituted Pyrazole Inhibitors of the Transforming Growth Factor-β Type I Receptor Kinase Domain
Source:
American Chemical Society (ACS)
Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities.
Source:
Elsevier BV
Development and therapeutic impact of HDAC6-selective inhibitors
Source:
Elsevier BV
Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth
Source:
American Chemical Society (ACS)
Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A.
Source:
American Chemical Society (ACS)
Ricolinostat, a selective HDAC6 inhibitor, shows anti-lymphoma cell activity alone and in combination with bendamustine
Source:
Springer Science and Business Media LLC
Development of a Potent and Selective HDAC8 Inhibitor.
Source:
American Chemical Society (ACS)
Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.
Source:
Springer Science and Business Media LLC
Epigenetics in Cancer
Source:
Oxford University Press (OUP)
Ricolinostat, the First Selective Histone Deacetylase 6 Inhibitor, in Combination with Bortezomib and Dexamethasone for Relapsed or Refractory Multiple Myeloma
Source:
American Association for Cancer Research (AACR)
Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness.
Source:
Impact Journals, LLC
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
Source:
American Association for the Advancement of Science (AAAS)
iCELLigence real-time cell analysis system for examining the cytotoxicity of drugs to cancer cell lines
Source:
Spandidos Publications
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.
Source:
Elsevier BV
Explorative study on isoform-selective histone deacetylase inhibitors.
Source:
Pharmaceutical Society of Japan
Crystal structure of a bacterial class 2 histone deacetylase homologue.
Source:
Elsevier BV
The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress
Source:
Cell Press.
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility
Source:
Cold Spring Harbor Laboratory
Epigenetic therapies for non-oncology indications.
Source:
Elsevier BV
The Role of HDAC6 in Cancer
Source:
Hindawi Limited
Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases
Source:
Elsevier Ltd.
Hdac6 knock-out increases tubulin acetylation but does not modify disease progression in the R6/2 mouse model of Huntington's disease.
Source:
Public Library of Science (PLoS)
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives.
Source:
Future Science Ltd
Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma
Source:
American Society of Hematology
Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Source:
Springer Science and Business Media LLC
The role of epigenetic mechanisms and processes in autoimmune disorders.
Source:
Informa UK Limited
Ricolinostat plus lenalidomide, and dexamethasone in relapsed or refractory multiple myeloma: a multicentre phase 1b trial
Source:
Elsevier BV
Design and Biological Evaluation of tetrahydro-β-carboline Derivatives as Highly Potent Histone Deacetylase 6 (HDAC6) Inhibitors
Source:
Elsevier BV
Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation
Source:
Elsevier Ltd.
Synthesis and characterization of two new hydroxamic acids derivatives and their metal complexes. An investigation on the keto/enol, E/Z and hydroxamate/hydroximate forms
Source:
Elsevier BV
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