Supplemental material
Open access
2,972
Views
23
CrossRef citations to date
0
Altmetric
Research Paper
Reprofiling of pyrimidine-based DAPK1/CSF1R dual inhibitors: identification of 2,5-diamino-4-pyrimidinol derivatives as novel potential anticancer lead compounds
Ahmed K. Faraga RI Translational Research Team, Division of Applied RI, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, Republic of KoreaCorrespondence[email protected] [email protected]
https://orcid.org/0000-0003-4420-3451View further author information
Ahmed H. E. Hassanb Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
https://orcid.org/0000-0002-1048-6281View further author information
Byung Sun Ahnc Chemical Kinomics Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea;d Division of Bio-Medical Science and Technology, KIST School, University of Science and Technology, Seoul, Republic of KoreaView further author information
, Ki Duk Parkd Division of Bio-Medical Science and Technology, KIST School, University of Science and Technology, Seoul, Republic of Korea;e Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, Republic of KoreaView further author information
& Eun Joo Rohc Chemical Kinomics Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea;d Division of Bio-Medical Science and Technology, KIST School, University of Science and Technology, Seoul, Republic of KoreaCorrespondence[email protected]
View further author information
View further author information
Pages 311-324
|
Received 13 Sep 2019, Accepted 25 Nov 2019, Published online: 06 Dec 2019
Related Research Data
CSF‐1 and its receptor in breast carcinomas and neoplasms of the female reproductive tract
Source:
Wiley
Elevated Expression of the Oncogene c-fms and Its Ligand, the Macrophage Colony-Stimulating Factor-1, in Cervical Cancer and the Role of Transforming Growth Factor-β1 in Inducing c-fms Expression
Source:
American Association for Cancer Research (AACR)
1,4-dioxane-fused 4-anilinoquinazoline as inhibitors of epidermal growth factor receptor kinase.
Source:
Wiley
Design, synthesis and cytotoxicity of chimeric erlotinib-alkylphospholipid hybrids.
Source:
Elsevier BV
High co-expression of IL-34 and M-CSF correlates with tumor progression and poor survival in lung cancers
Source:
Nature Publishing Group
Design, synthesis and biological evaluation of WZ4002 analogues as EGFR inhibitors
Source:
Elsevier BV
A Review on Synthesis, Anticancer and Antiviral Potentials of Pyrimidine Derivatives
Source:
Bentham Science Publishers Ltd.
Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents.
Source:
Elsevier BV
EGFR inhibitors from cancer to inflammation: Discovery of 4-fluoro-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide as a novel anti-inflammatory EGFR inhibitor.
Source:
Elsevier BV
Anti-Cancer Pyrimidines in Diverse Scaffolds: A Review of Patent Literature
Source:
Bentham Science Publishers Ltd.
Death-associated protein kinase (DAPK) family modulators: Current and future therapeutic outcomes.
Source:
Wiley
Prognostic significance of tumor-associated macrophages in endometrial adenocarcinoma.
Source:
Elsevier BV
Prognostic significance of tumor-associated macrophages in ovarian cancer: A meta-analysis
Source:
Elsevier BV
Novel LCK/FMS inhibitors based on phenoxypyrimidine scaffold as potential treatment for inflammatory disorders.
Source:
Elsevier BV
Zipper-interacting Protein Kinase (ZIPK) Modulates Canonical Wnt/β-Catenin Signaling through Interaction with Nemo-like Kinase and T-cell Factor 4 (NLK/TCF4)
Source:
Elsevier BV
Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity
Source:
Springer Science and Business Media LLC
Macrophage Susceptibility to Emactuzumab (RG7155) Treatment.
Source:
American Association for Cancer Research (AACR)
NCATS launches drug repurposing program
Source:
Springer Science and Business Media LLC
ZIP kinase plays a crucial role in androgen receptor-mediated transcription.
Source:
Springer Science and Business Media LLC
Natural products hybrids: 3,5,4′-Trimethoxystilbene-5,6,7-trimethoxyflavone chimeric analogs as potential cytotoxic agents against diverse human cancer cells
Source:
Elsevier BV
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.