Synthesis and characterisation of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity

M. Alia Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia

Assem Barakata Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia;b Department of Chemistry, Faculty of Science, Alexandria University, Ibrahimia, EgyptCorrespondence[email protected]

Ayman El-Fahama Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia;b Department of Chemistry, Faculty of Science, Alexandria University, Ibrahimia, EgyptCorrespondence[email protected]

Hessa H. Al-Rasheeda Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia

Kholoud Dahlousa Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia

Abdullah Mohammed Al-Majida Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia

Anamika Sharmac Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa;d KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa

Sammer Yousufe H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Mehar Sanamf Dr. Panjwani Center for Molecular medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Zaheer Ul-Haqf Dr. Panjwani Center for Molecular medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

M. Iqbal Choudharye H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan;f Dr. Panjwani Center for Molecular medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

Beatriz G. de la Torred KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa

Fernando Albericioa Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia;c Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa;g CIBER-BBN, Networking Centre on Bioengineering, Biomaterials and Nanomedicine, and Department of Organic Chemistry, University of Barcelona, Barcelona, Spain

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Synthesis and characterisation of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity

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Synthesis and characterisation of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity

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