Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design, synthesis, molecular docking studies and ADMET prediction

Tarek S. Ibrahima Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia;b Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig, EgyptCorrespondence[email protected] [email protected]
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Amr H. Moustafac Department of Chemistry, Faculty of Science, Sohag University, Sohag, Egypt

Ahmad J. Almalkia Department of Pharmaceutical Chemistry, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi ArabiaView further author information

Rasha M. Allamd Pharmacology Department, National Research Centre, Cairo, EgyptView further author information

Abdulhamid Althagafie Department of Pharmacy Practice, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi ArabiaView further author information

Shadab Mdf Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi ArabiaView further author information

Mamdouh F. A. Mohamedg Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag, EgyptCorrespondence[email protected] [email protected]

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