Imparting aromaticity to 2-pyridone derivatives by O-alkylation resulted in new competitive and non-competitive PIM-1 kinase inhibitors with caspase-activated apoptosis

Marwa E. Abdelaziza Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, EgyptCorrespondence[email protected]
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Mostafa M. M. El-Miligya Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt

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Salwa M. Fahmya Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, EgyptView further author information

Marwa M. Abu-Serieb Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), City of Scientific Research and Technological Applications (SRTA-City), Alexandria, EgyptView further author information

Aly A. Hazzaaa Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, EgyptView further author information

Mona A. Mahrana Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, EgyptView further author information

Imparting aromaticity to 2-pyridone derivatives by O-alkylation resulted in new competitive and non-competitive PIM-1 kinase inhibitors with caspase-activated apoptosis

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Imparting aromaticity to 2-pyridone derivatives by O-alkylation resulted in new competitive and non-competitive PIM-1 kinase inhibitors with caspase-activated apoptosis

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