Supplemental material
Cell Cycle
Volume 17, 2018 - Issue 5
Reports
Discovery of thalicthuberine as a novel antimitotic agent from nature that disrupts microtubule dynamics and induces apoptosis in prostate cancer cells
Claire LevrierAustralian Prostate Cancer Research Centre−Queensland, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Princess Alexandra Hospital, Translational Research Institute, Brisbane, QLD, Australia;Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, Australia
http://orcid.org/0000-0003-0439-0176View further author information
http://orcid.org/0000-0003-0439-0176View further author information, Anja RockstrohAustralian Prostate Cancer Research Centre−Queensland, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Princess Alexandra Hospital, Translational Research Institute, Brisbane, QLD, Australiahttp://orcid.org/0000-0002-2700-375XView further author information
http://orcid.org/0000-0002-2700-375XView further author information, Brian GabrielliThe University of Queensland Diamantina Institute; Translational Research Institute; Brisbane, QLD, Australiahttp://orcid.org/0000-0003-3933-1651View further author information
http://orcid.org/0000-0003-3933-1651View further author information, Maria KavallarisTumour Biology and Targeting Program, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Australia, Sydney, NSW, Australia;ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and Australian Centre for NanoMedicine, UNSW Australia, Sydney, NSW, Australiahttp://orcid.org/0000-0003-2309-898XView further author information
http://orcid.org/0000-0003-2309-898XView further author information, Melanie LehmanAustralian Prostate Cancer Research Centre−Queensland, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Princess Alexandra Hospital, Translational Research Institute, Brisbane, QLD, Australia;Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Vancouver, Canadahttp://orcid.org/0000-0003-0500-2411View further author information
http://orcid.org/0000-0003-0500-2411View further author information, Rohan A. DavisAustralian Prostate Cancer Research Centre−Queensland, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Princess Alexandra Hospital, Translational Research Institute, Brisbane, QLD, Australia;Griffith Institute for Drug Discovery, Griffith University, Brisbane, QLD, Australiahttp://orcid.org/0000-0003-4291-7573View further author information
http://orcid.org/0000-0003-4291-7573View further author information, Martin C. SadowskiAustralian Prostate Cancer Research Centre−Queensland, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Princess Alexandra Hospital, Translational Research Institute, Brisbane, QLD, Australiahttp://orcid.org/0000-0002-5267-1442View further author information
http://orcid.org/0000-0002-5267-1442View further author information & Colleen C. NelsonAustralian Prostate Cancer Research Centre−Queensland, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Princess Alexandra Hospital, Translational Research Institute, Brisbane, QLD, AustraliaCorrespondence[email protected]
http://orcid.org/0000-0001-6410-4843View further author information
http://orcid.org/0000-0001-6410-4843View further author information show allRelated Research Data
Microtubules as a target for anticancer drugs.
Source:
Springer Science and Business Media LLC
Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1.: Phosphorylation of beta tubulin by Cdk1
Source:
HAL CCSD
CellProfiler: image analysis software for identifying and quantifying cell phenotypes
Source:
Springer Science and Business Media LLC
A new convenient synthesis of phenanthrene alkaloids from 1-arylmethyl-1,2,3,4-tetrahydroisoquinolines
Source:
Elsevier BV
Analysis of microtubule dynamic instability using a plus-end growth marker
Source:
Springer Science and Business Media LLC
A novel anti-microtubule agent with carbazole and benzohydrazide structures suppresses tumor cell growth in vivo
Source:
Elsevier BV
H3-Ser28 phosphorylation by Aurora-B
Source:
Wiley
Discovery of Thalicthuberine as a Novel Antimitotic Agent from Nature that Disrupts Microtubule Dynamics and Induces Apoptosis in Prostate Cancer Cells
Source:
Taylor & Francis
Alkaloids from Platycapnos spicata
Source:
Elsevier BV
Cancer Cell Cycles
Source:
American Association for the Advancement of Science (AAAS)
The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells.
Source:
Impact Journals, LLC
A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells
Source:
Elsevier BV
Aurora inhibitor MLN8237 in combination with docetaxel enhances apoptosis and anti-tumor activity in mantle cell lymphoma
Source:
Elsevier BV
GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists
Source:
BMC
Regulation of microtubule, apoptosis, and cell cycle-related genes by taxotere in prostate cancer cells analyzed by microarray
Source:
Neoplasia Press, Inc. Published by Elsevier Inc.
NuSAP is essential for chromatin-induced spindle formation during early embryogenesis
Source:
The Company of Biologists
Identification of dual DNA-PK MDR1 inhibitors for the potentiation of cytotoxic drug activity.
Source:
Elsevier BV
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
Source:
Springer Science and Business Media LLC
MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.
Source:
Springer Science and Business Media LLC
Alkaloids of Thalictrum XXX. Eleven Minor Alkaloids From Thalictrum rugosum
Source:
American Chemical Society (ACS)
Discovery and development of the Polo-like kinase inhibitor volasertib in cancer therapy.
Source:
Springer Science and Business Media LLC
Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine.
Source:
American Chemical Society (ACS)
Identification of a Novel Protein Regulating Microtubule Stability through a Chemical Approach
Source:
Elsevier BV
Alkaloids of Thalictrum delavayi.
Source:
Elsevier BV
Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation
Source:
Rockefeller University Press
Synthesis of Thalicthuberine
Source:
Wiley
CIPN: A Critical Analysis
Source:
Wiley
Differential Effects of Tissue Culture Coating Substrates on Prostate Cancer Cell Adherence, Morphology and Behavior
Source:
Public Library of Science (PLoS)
Microtubule-associated proteins as targets in cancer chemotherapy.
Source:
American Association for Cancer Research (AACR)
Phenotypic Characterization of Prostate Cancer LNCaP Cells Cultured within a Bioengineered Microenvironment
Source:
Public Library of Science (PLoS)
Isoquinoline alkaloids from Platycapnos
Source:
Elsevier BV
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