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Research Paper - Translational
Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency
Parisa LotfiDepartment of Molecular and Human Genetics, Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, Houston, TX, USAView further author information
, Dennis Y. TseDepartment of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA;School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong KongView further author information
, Alberto Di RonzaDepartment of Molecular and Human Genetics, Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, Houston, TX, USAView further author information
, Michelle L. SeymourHuffington Center on Aging, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA;Department of Otolaryngology–Head & Neck Surgery, Baylor College of Medicine, Houston, TX, USAView further author information
, Giuseppe MartanoCNR Institute of Neuroscience, Milan, ItalyView further author information
, Jonathan D. CooperDepartment of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK;Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, David Geffen School of Medicine, UCLA, Torrance, CA, USAView further author information
, Fred A. PereiraHuffington Center on Aging, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA;Department of Otolaryngology–Head & Neck Surgery, Baylor College of Medicine, Houston, TX, USAView further author information
, Maria PassafaroCNR Institute of Neuroscience, Milan, ItalyView further author information
, Samuel M. WuDepartment of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USAView further author information
& Marco SardielloDepartment of Molecular and Human Genetics, Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, Houston, TX, USACorrespondence[email protected]
View further author information
show allView further author information
Pages 1419-1434
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Received 18 Sep 2017, Accepted 02 May 2018, Published online: 23 Jul 2018
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Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency
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Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency
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Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency
Source:
Figshare
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