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Autophagy Volume 20, 2024 - Issue 1
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Research Paper

Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer

Weihao Lia State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaCorrespondence[email protected]
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Chi Zhoua State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaCorrespondence[email protected]
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Long Yua State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaCorrespondence[email protected]
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Zhenlin Houa State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaView further author information
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Huashan Liuc Department of Colorectal Surgery and Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, ChinaView further author information
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Lingheng Konga State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaView further author information
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Yanbo Xua State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaView further author information
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Jiahua Hea State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaView further author information
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Jin Lana State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaView further author information
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Qingjian Oua State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaView further author information
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Yujing Fanga State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaView further author information
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Zhenhai Lua State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaView further author information
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Xiaojun Wua State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaView further author information
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Zhizhong Pana State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaCorrespondence[email protected]
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Jianhong Penga State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaCorrespondence[email protected]
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Junzhong Lina State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China;b Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, ChinaCorrespondence[email protected]
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Pages 114-130 | Received 21 Feb 2023, Accepted 13 Aug 2023, Published online: 29 Aug 2023

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