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Springer Nature
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Figshare
Accurate extension of multiple sequence alignments using a phylogeny-aware graph algorithm
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Oxford University Press (OUP)
Computational Method to Predict Mitochondrially Imported Proteins and their Targeting Sequences
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Wiley
A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood.
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HAL CCSD
Cross Talk between Cellular Regulatory Networks Mediated by Shared Proteins
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Hindawi Limited
Protein biosynthesis in organelles requires misaminoacylation of tRNA
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Springer Nature
An Efficient Genetic Screen in Drosophila to Identify Nuclear-Encoded Genes With Mitochondrial Function
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Genetics Society of America
To charge or not to charge: mechanistic insights into neuropathy-associated tRNA synthetase mutations
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Elsevier BV
Aminoacyl-tRNA synthetases and tumorigenesis: more than housekeeping.
Source:
Springer Science and Business Media LLC
Dominant, toxic gain-of-function mutations ingarslead to non-cell autonomous neuropathology
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Oxford University Press (OUP)
Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy
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Springer Nature
Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate inDrosophilafeatures of human Charcot–Marie–Tooth neuropathy
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Proceedings of the National Academy of Sciences
The aminoacyl-tRNA synthetases of Drosophila melanogaster
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Figshare
Biogenesis of glutaminyl-mt tRNAGln in human mitochondria
Source:
Proceedings of the National Academy of Sciences
Double-sieving-defective aminoacyl-tRNA synthetase causes protein mistranslation and affects cellular physiology and development
Source:
Springer Nature
New functions of aminoacyl-tRNA synthetases beyond translation
Source:
Springer Nature
Drosophila as a Model for Human Neurodegenerative Disease
Source:
Annual Reviews
The Role of Aminoacyl-tRNA Synthetases in Genetic Diseases
Source:
Annual Reviews
Mammalian aminoacyl-tRNA synthetases: Cell signaling functions of the protein translation machinery
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Elsevier BV
Proofreading and Aminoacylation of tRNAs Before Export from the Nucleus
Source:
American Association for the Advancement of Science (AAAS)
Evolution of the aminoacyl-tRNA synthetase family and the organization of the Drosophila glutamyl-prolyl-tRNA synthetase gene. Intron/exon structure of the gene, control of expression of the two mRNAs, selective advantage of the multienzyme complex.
Source:
European journal of biochemistry
A component of the multisynthetase complex is a multifunctional aminoacyl-tRNA synthetase.
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The EMBO journal
Charcot-Marie-Tooth Disease
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SAGE Publications
Aminoacyl-tRNA Synthetases: General Features and Recognition of Transfer RNAs
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Annual Reviews
Human mitochondrial disease-like symptoms caused by a reduced tRNA aminoacylation activity in flies
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Oxford University Press (OUP)
Structural and functional considerations of the aminoacylation reaction
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Elsevier BV
Pleiotropic Effects of a Mitochondrial–Nuclear Incompatibility Depend upon the Accelerating Effect of Temperature in Drosophila
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Genetics Society of America
A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway.
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Public Library of Science (PLoS)
The second genetic code
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Springer Nature
New Aminoacyl-tRNA Synthetase-like Protein in Insecta with an Essential Mitochondrial Function
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American Society for Biochemistry & Molecular Biology (ASBMB)
Charcot-Marie-Tooth Disease
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SAGE Publications
Mitochondrial aminoacyl-tRNA synthetases in human disease
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Elsevier BV
Improving the efficiency of SPR moves in phylogenetic tree search methods based on maximum likelihood
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Oxford University Press (OUP)
Effect of mini-tyrosyl-tRNA synthetase on ischemic angiogenesis, leukocyte recruitment, and vascular permeability
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American Physiological Society
CMT-associated mutations in glycyl- and tyrosyl-tRNA synthetases exhibit similar pattern of toxicity and share common genetic modifiers in Drosophila
Source:
Elsevier BV
Expression and characterization of a human mitochondrial phenylalanyl-tRNA synthetase 1 1Edited by D. E. Draper
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Elsevier BV
Charcot-Marie-Tooth Disease
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SAGE Publications
A Drosophila model for mito-nuclear diseases generated by an incompatible interaction between tRNA and tRNA synthetase
Source:
The Company of Biologists
Impaired protein translation in Drosophila models for Charcot–Marie–Tooth neuropathy caused by mutant tRNA synthetases
Source:
Springer Nature
Mutations in the Mitochondrial Methionyl-tRNA Synthetase Cause a Neurodegenerative Phenotype in Flies and a Recessive Ataxia (ARSAL) in Humans
Source:
Public Library of Science (PLoS)
Charcot-Marie-Tooth Disease
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SAGE Publications
The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript.
Source:
The Journal of biological chemistry
The aminoacyl-tRNA synthetases of Drosophila melanogaster
Source:
Figshare
Charcot-Marie-Tooth Disease
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SAGE Publications
WRS-85D: A Tryptophanyl-tRNA Synthetase Expressed to High Levels in the Developing Drosophila Salivary Gland
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American Society for Cell Biology (ASCB)
Charcot-Marie-Tooth Disease
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SAGE Publications
An Incompatibility between a mitochondrial tRNA and its nuclear-encoded tRNA synthetase compromises development and fitness in Drosophila.
Source:
PLoS genetics
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