Microbial metabolite butyrate promotes anti-PD-1 antitumor efficacy by modulating T cell receptor signaling of cytotoxic CD8 T cell

Xinhai Zhua Department of Oncology, First Affiliated Hospital, Jinan University, Guangzhou, ChinaView further author information

Ke Lib Department of Geriatrics, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, ChinaView further author information

Guichao Liuc Department of Head and Neck Breast Radiotherapy, The First People’s Hospital of Foshan City, Foshan, China;d The First Affiliated Hospital, Jinan University, Guangzhou, ChinaView further author information

Ruan Wue Center for Disease Control and Prevention, Anhui Provincial Center for Disease Control and Prevention, Hefei, ChinaView further author information

Yan Zhanga Department of Oncology, First Affiliated Hospital, Jinan University, Guangzhou, ChinaView further author information

Siying Wangf Department of Breast Surgery, First Affiliated Hospital, Jinan University, Guangzhou, ChinaView further author information

Meng Xua Department of Oncology, First Affiliated Hospital, Jinan University, Guangzhou, ChinaCorrespondence[email protected]
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Ligong Lug Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People’s Hospital Affiliated with Jinan University, Zhuhai, ChinaCorrespondence[email protected]
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Peng Lig Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People’s Hospital Affiliated with Jinan University, Zhuhai, China;h The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, ChinaCorrespondence[email protected]

https://orcid.org/0000-0001-5518-9822 View further author information

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Microbial metabolite butyrate promotes anti-PD-1 antitumor efficacy by modulating T cell receptor signaling of cytotoxic CD8 T cell

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Microbial metabolite butyrate promotes anti-PD-1 antitumor efficacy by modulating T cell receptor signaling of cytotoxic CD8 T cell

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