Combined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis

Monika DadrichDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany;Department of Radiology, University Hospital Center, 400 INF, Heidelberg, Germany

Nils H. NicolayDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany;Department of Radiation Oncology, University Hospital Center, 400 INF, Heidelberg, GermanyCorrespondence[email protected]

Paul FlechsigDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany;Department of Radiology, University Hospital Center, 400 INF, Heidelberg, Germany

Sebastian BickelhauptDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany

Line HoeltgenDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany

Falk RoederDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany;Department of Radiation Oncology, University Hospital Center, 400 INF, Heidelberg, Germany;Department of Radiation Oncology, Ludwig-Maximilians University Munich, Munich, Germany

Kai HauserDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany

Alexandra TietzDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany

Jürgen JenneDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany

Ramon LopezDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany

Manuel RoehrichDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany

Ute WirknerDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany

Michael LahnOncology Early Clinical Investigation, Lilly Research Laboratories, Indianapolis, IN, USA

Peter E. HuberDepartment of Molecular & Radiation Oncology, German Cancer Research Center (DKFZ), 280 INF, Heidelberg, Germany;Department of Radiation Oncology, University Hospital Center, 400 INF, Heidelberg, Germany

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Combined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis

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Combined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis

KONI_A_1123366_supplemental_material.zip

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