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OncoImmunology Volume 6, 2017 - Issue 3
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Original Research

PD-L1 (CD274) copy number gain, expression, and immune cell infiltration as candidate predictors for response to immune checkpoint inhibitors in soft-tissue sarcoma

Jan BudcziesInstitute of Pathology, Charité University Hospital, Berlin, Germany;German Cancer Consortium (DKTK), partner sites Heidelberg and Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany
,
Gunhild MechtersheimerInstitute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
,
Carsten DenkertInstitute of Pathology, Charité University Hospital, Berlin, Germany;German Cancer Consortium (DKTK), partner sites Heidelberg and Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany
,
Frederick KlauschenInstitute of Pathology, Charité University Hospital, Berlin, Germany
,
Sadaf S. MughalDivision of Applied Bioinformatics, German Cancer Research Center (DKFZ) and National Center for Tumor Disease (NCT) Heidelberg, Heidelberg, GermanyORCID Iconhttp://orcid.org/0000-0003-3468-8467
ORCID Icon,
Priya ChudasamaDepartment of Translational Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ), Heidelberg, GermanyORCID Iconhttp://orcid.org/0000-0002-0754-4436
ORCID Icon,
Michael BockmayrInstitute of Pathology, Charité University Hospital, Berlin, GermanyORCID Iconhttp://orcid.org/0000-0002-9249-4292
ORCID Icon,
Korinna JöhrensInstitute of Pathology, Charité University Hospital, Berlin, Germany
,
Volker EndrisInstitute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
,
Amelie LierInstitute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
,
Felix LasitschkaInstitute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
,
Roland PenzelInstitute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
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Manfred DietelInstitute of Pathology, Charité University Hospital, Berlin, Germany;German Cancer Consortium (DKTK), partner sites Heidelberg and Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany
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Benedikt BrorsGerman Cancer Consortium (DKTK), partner sites Heidelberg and Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany;Division of Applied Bioinformatics, German Cancer Research Center (DKFZ) and National Center for Tumor Disease (NCT) Heidelberg, Heidelberg, Germany
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Stefan GröschelDepartment of Translational Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ), Heidelberg, Germany;Section for Personalized Oncology, Heidelberg University Hospital, Heidelberg, Germany
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Hanno GlimmGerman Cancer Consortium (DKTK), partner sites Heidelberg and Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany;Department of Translational Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ), Heidelberg, Germany;Section for Personalized Oncology, Heidelberg University Hospital, Heidelberg, Germany
,
Peter SchirmacherGerman Cancer Consortium (DKTK), partner sites Heidelberg and Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany;Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
,
Marcus RennerInstitute of Pathology, University Hospital Heidelberg, Heidelberg, Germany
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Stefan FröhlingGerman Cancer Consortium (DKTK), partner sites Heidelberg and Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany;Department of Translational Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ), Heidelberg, Germany;Section for Personalized Oncology, Heidelberg University Hospital, Heidelberg, Germany
&
Albrecht StenzingerGerman Cancer Consortium (DKTK), partner sites Heidelberg and Berlin, and German Cancer Research Center (DKFZ), Heidelberg, Germany;Institute of Pathology, University Hospital Heidelberg, Heidelberg, GermanyCorrespondence[email protected]
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Article: e1279777 | Received 01 Aug 2016, Accepted 04 Jan 2017, Published online: 07 Mar 2017

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