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Human Vaccines & Immunotherapeutics Volume 18, 2022 - Issue 1
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Coronavirus – Research Paper

Comparison of Wild Type DNA Sequence of Spike Protein from SARS-CoV-2 with Optimized Sequence on The Induction of Protective Responses Against SARS-Cov-2 Challenge in Mouse Model

Sheng Jianga Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College (SHMC), Fudan University, Shanghai, China;b National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, ChinaView further author information
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Shuting Wua Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College (SHMC), Fudan University, Shanghai, ChinaView further author information
,
Gan Zhaoc Biomedical Research Institute of Advaccine (BRIA), Advaccine Biopharmaceutics (Suzhou) Co. LTD, Suzhou City, JiangsuView further author information
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Yue Hec Biomedical Research Institute of Advaccine (BRIA), Advaccine Biopharmaceutics (Suzhou) Co. LTD, Suzhou City, JiangsuView further author information
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Linlin Baod Key Laboratory of Human Disease Comparative Medicine, Chinese Ministry of Health, Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious Diseases, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College (PUMC), Beijing, ChinaView further author information
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Jiangning Liud Key Laboratory of Human Disease Comparative Medicine, Chinese Ministry of Health, Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious Diseases, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College (PUMC), Beijing, ChinaView further author information
,
Chuan Qind Key Laboratory of Human Disease Comparative Medicine, Chinese Ministry of Health, Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious Diseases, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College (PUMC), Beijing, ChinaView further author information
,
Jiawang Houc Biomedical Research Institute of Advaccine (BRIA), Advaccine Biopharmaceutics (Suzhou) Co. LTD, Suzhou City, JiangsuView further author information
,
Yuan Dingc Biomedical Research Institute of Advaccine (BRIA), Advaccine Biopharmaceutics (Suzhou) Co. LTD, Suzhou City, JiangsuView further author information
,
Alex Chengc Biomedical Research Institute of Advaccine (BRIA), Advaccine Biopharmaceutics (Suzhou) Co. LTD, Suzhou City, JiangsuView further author information
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Brian Jiangc Biomedical Research Institute of Advaccine (BRIA), Advaccine Biopharmaceutics (Suzhou) Co. LTD, Suzhou City, JiangsuView further author information
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John Wuc Biomedical Research Institute of Advaccine (BRIA), Advaccine Biopharmaceutics (Suzhou) Co. LTD, Suzhou City, JiangsuView further author information
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Jian Yane Inovio Pharmaceuticals, Plymouth Meeting, PA, USAView further author information
,
Laurent Humeaue Inovio Pharmaceuticals, Plymouth Meeting, PA, USAView further author information
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Ami Patellae Inovio Pharmaceuticals, Plymouth Meeting, PA, USAView further author information
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David B. Weinerf The Wistar Institute, Philadelphia, PA, USAView further author information
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Kate Brodericke Inovio Pharmaceuticals, Plymouth Meeting, PA, USAView further author information
&
Bin Wanga Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Medical College (SHMC), Fudan University, Shanghai, China;b National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-9945-1818View further author information
ORCID Icon show all
Article: 2016201 | Received 16 Aug 2021, Accepted 02 Dec 2021, Published online: 21 Jan 2022

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