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Emerging Microbes & Infections Volume 8, 2019 - Issue 1
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Original Articles

Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice

Yan Liua Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, People’s Republic of ChinaView further author information
,
Yi Zhoub Department of Infectious Diseases, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of ChinaView further author information
,
Xiaodong Lia Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, People’s Republic of ChinaView further author information
,
Ming Niuc Institute of Chinese Medicine, Beijing 302 Hospital, Beijing, People’s Republic of ChinaView further author information
,
Rongjuan Chena Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, People’s Republic of ChinaView further author information
,
Jinman Shaoa Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, People’s Republic of ChinaView further author information
,
Lanlan Sia Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, People’s Republic of ChinaView further author information
,
Dan Luob Department of Infectious Diseases, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of ChinaView further author information
,
Yayun Linb Department of Infectious Diseases, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of ChinaView further author information
,
Le Lia Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, People’s Republic of ChinaView further author information
,
Kai Zhangb Department of Infectious Diseases, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of ChinaView further author information
,
Xiaohe Xiaoc Institute of Chinese Medicine, Beijing 302 Hospital, Beijing, People’s Republic of ChinaView further author information
,
Zhihui Xua Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, People’s Republic of ChinaView further author information
,
Min Liub Department of Infectious Diseases, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of ChinaView further author information
,
Mengji Lud Institute of Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, GermanyCorrespondence[email protected]
View further author information
,
Fabien Zoulime Univ Lyon, Universite Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Leon Berard, Centre de recherche en cancerologie de Lyon, Lyon, France;f Department of Hepatology, Groupement Hospitalier Nord, Hospices Civils de Lyon, Lyon, FranceCorrespondence[email protected]
View further author information
&
Dongping Xua Institute of Infectious Diseases, Beijing 302 Hospital, Beijing, People’s Republic of ChinaCorrespondence[email protected]
View further author information
 show all
Pages 354-365 | Received 19 Jul 2018, Accepted 01 Feb 2019, Published online: 08 Mar 2019

Related Research Data

Comparison of Detection Rate and Mutational Pattern of Drug-Resistant Mutations Between a Large Cohort of Genotype B and Genotype C Hepatitis B Virus-Infected Patients in North China.
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Long-term monitoring shows hepatitis B virus resistance to entecavir in nucleoside-naïve patients is rare through 5 years of therapy.
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Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice
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Mechanistic Characterization and Molecular Modeling of Hepatitis B Virus Polymerase Resistance to Entecavir
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Guideline of Prevention and Treatment for Chronic Hepatitis B (2015 Update).
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The rtA181S mutation of hepatitis B virus primarily confers resistance to adefovir dipivoxil
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Evolution and suppression of HBV strains with multidrug resistance to lamivudine, adefovir dipivoxil and entecavir in a patient with chronic hepatitis B.
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