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Emerging Microbes & Infections Volume 11, 2022 - Issue 1
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Antimicrobial Agents

Cryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides

Wen Zhanga Institutes of Biomedical Sciences, Fudan University, Shanghai, People’s Republic of China;b Fudan University Pudong Medical Center, Department of Systems Biology for Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, ChinaORCID Iconhttps://orcid.org/0000-0002-4973-1168View further author information
ORCID Icon,
ZhiFei Lic State Key Laboratory of Membrane Biology, National Biomedical Imaging Center, Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Peking University, Beijing, People’s Republic of China;d China National Center for Biotechnology Development, Beijing, People’s Republic of ChinaView further author information
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Yufan Sune Department of Medical Microbiology, Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information
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Peng Cuif Department of Infectious Diseases, National Medical Center for Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of ChinaView further author information
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Jianhua Liangg School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, People’s Republic of ChinaView further author information
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Qinghe Xinga Institutes of Biomedical Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information
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Jing Wuf Department of Infectious Diseases, National Medical Center for Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of ChinaView further author information
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Yanhui Xua Institutes of Biomedical Sciences, Fudan University, Shanghai, People’s Republic of ChinaView further author information
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Wenhong Zhangf Department of Infectious Diseases, National Medical Center for Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of ChinaCorrespondence[email protected]
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Ying Zhangf Department of Infectious Diseases, National Medical Center for Infectious Diseases, Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of China;h State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence[email protected]
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Lin Hea Institutes of Biomedical Sciences, Fudan University, Shanghai, People’s Republic of China;i Bio-X Institute, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, People’s Republic of ChinaCorrespondence[email protected]
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&
Ning Gaoc State Key Laboratory of Membrane Biology, National Biomedical Imaging Center, Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Peking University, Beijing, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3067-9993View further author information
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Pages 293-305 | Received 18 Oct 2021, Accepted 20 Dec 2021, Published online: 21 Jan 2022

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