Resistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistance

Jochem B. Buila Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands;b Radboudumc-CWZ Center of Expertise for Mycology, Nijmegen, NetherlandsCorrespondence[email protected]
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Jason D. Oliverc F2G Ltd, Manchester, UKView further author information

Derek Lawc F2G Ltd, Manchester, UKView further author information

Tim Baltussena Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, NetherlandsView further author information

Jan Zolla Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands;b Radboudumc-CWZ Center of Expertise for Mycology, Nijmegen, NetherlandsView further author information

Margriet W. J. Hokkena Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, NetherlandsView further author information

Marlou Tehupeiory-Kooremana Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands;b Radboudumc-CWZ Center of Expertise for Mycology, Nijmegen, NetherlandsView further author information

Willem J. G. Melchersa Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands;b Radboudumc-CWZ Center of Expertise for Mycology, Nijmegen, NetherlandsView further author information

Mike Birchc F2G Ltd, Manchester, UKView further author information

Paul E. Verweija Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands;b Radboudumc-CWZ Center of Expertise for Mycology, Nijmegen, NetherlandsView further author information

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Resistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistance

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Resistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistance

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