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Emerging Microbes & Infections
Volume 11, 2022 - Issue 1
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Coronaviruses
A tandem-repeat dimeric RBD protein-based covid-19 vaccine zf2001 protects mice and nonhuman primates
Yaling Ana Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 101408, People’s Republic of China;b CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of ChinaView further author information
, Shihua Lib CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of ChinaView further author information
, Xiyue Jinc School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, 230026, People’s Republic of ChinaView further author information
, Jian-bao Hand Kunming National High-Level Biosafety Research Center for Non-human Primates, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650107, People’s Republic of ChinaView further author information
, Kun Xue Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Tropical Medicine and Laboratory Medicine, The First Affiliated Hospital, Hainan Medical University, Hainan, 571199, People’s Republic of China;f Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of China
https://orcid.org/0000-0002-9762-5001View further author information
Senyu Xuf Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of ChinaView further author information
, Yuxuan Hana Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 101408, People’s Republic of China;b CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of ChinaView further author information
, Chuanyu Liug Laboratory of Animal Infectious Diseases, College of Animal Sciences and Veterinary Medicine, Guangxi University, Nanning, 530000, People’s Republic of ChinaView further author information
, Tianyi Zhengf Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of China;p Zhejiang University School of Medicine, Hangzhou310058, People’s Republic of ChinaView further author information
, Mei Liuh CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of ChinaView further author information
, Mi Yangh CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of ChinaView further author information
, Tian-Zhang Songi Key Laboratory of Animal Models and Human Disease Mechanism of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academic of Sciences, Kunming, 650223, People’s Republic of ChinaView further author information
, Baoying Huangj NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People’s Republic of ChinaView further author information
, Li Zhaoj NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People’s Republic of ChinaView further author information
, Wen Wangj NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People’s Republic of ChinaView further author information
, Ruhan Aj NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People’s Republic of ChinaView further author information
, Yingjie Chengk Anhui Zhifei Longcom Biopharmaceutical Co. Ltd, Anhui, 230088, People’s Republic of ChinaView further author information
, Changwei Wuk Anhui Zhifei Longcom Biopharmaceutical Co. Ltd, Anhui, 230088, People’s Republic of ChinaView further author information
, Enqi Huangk Anhui Zhifei Longcom Biopharmaceutical Co. Ltd, Anhui, 230088, People’s Republic of ChinaView further author information
, Shilong Yangk Anhui Zhifei Longcom Biopharmaceutical Co. Ltd, Anhui, 230088, People’s Republic of ChinaView further author information
, Gary Wongl CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai200031, People’s Republic of China;m Department of Microbiology-Infectiology and Immunology, Laval University, Quebec CityG1, CanadaView further author information
, Yuhai Bib CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of China;n CAS Center for Influenza Research and Early-Warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), Chinese Academy of Sciences, Beijing, People’s Republic of China
https://orcid.org/0000-0002-5595-363XView further author information
Changwen Keo Guangdong Provincial Center for Disease Control and Prevention, Guangzhou511430, People’s Republic of ChinaView further author information
, Wenjie Tanj NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People’s Republic of ChinaCorrespondence[email protected]
View further author information
, View further author information
Jinghua Yanb CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of China;h CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of ChinaCorrespondence[email protected]
https://orcid.org/0000-0003-0502-3829View further author information
Yong-Tang Zhengd Kunming National High-Level Biosafety Research Center for Non-human Primates, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650107, People’s Republic of China;i Key Laboratory of Animal Models and Human Disease Mechanism of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academic of Sciences, Kunming, 650223, People’s Republic of ChinaCorrespondence[email protected]
View further author information
, View further author information
Lianpan Daia Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 101408, People’s Republic of China;b CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of China;e Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Tropical Medicine and Laboratory Medicine, The First Affiliated Hospital, Hainan Medical University, Hainan, 571199, People’s Republic of ChinaCorrespondence[email protected]
https://orcid.org/0000-0001-8352-1327View further author information
George F. Gaoa Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 101408, People’s Republic of China;b CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of China;f Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, People’s Republic of China;j NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People’s Republic of China;p Zhejiang University School of Medicine, Hangzhou310058, People’s Republic of ChinaCorrespondence[email protected]
https://orcid.org/0000-0002-3869-615XView further author information
Pages 1058-1071
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Received 17 Jan 2022, Accepted 17 Mar 2022, Published online: 11 Apr 2022
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